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5-MeO-DMT

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Identification
Molecular formula
C13H18ClN2O
CAS number
1019-45-0
IUPAC name
2-(5-methoxy-1H-indol-3-yl)ethanamine;hydrochloride
State
State

At room temperature, 5-MeO-DMT hydrochloride is a solid compound. It is usually stored in a cool, dry place to prevent degradation.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
372.68
Boiling point (Kelvin)
645.83
General information
Molecular weight
218.71g/mol
Molar mass
218.7130g/mol
Density
1.3600g/cm3
Appearence

5-MeO-DMT hydrochloride typically appears as a white to off-white crystalline powder, often clumpy or with fine granules. It is sensitive to humidity and light, which might lead to yellowing if not stored properly.

Comment on solubility

Solubility of 2-(5-methoxy-1H-indol-3-yl)ethanamine;hydrochloride

The solubility of 2-(5-methoxy-1H-indol-3-yl)ethanamine;hydrochloride (C13H18ClN2O) is a critical aspect to understand when considering its applications in pharmaceutical and chemical research. This compound, being a hydrochloride salt, typically exhibits increased solubility in aqueous solutions compared to its free base form. Here are some key points regarding its solubility:

  • Aqueous Solubility: The hydrochloride form is generally highly soluble in water due to the ionic nature of the chloride counterion.
  • Organic Solvents: It may exhibit variable solubility in organic solvents; for example, solubility in ethanol or methanol can be noteworthy for various applications, though specific conditions must be considered.
  • pH Conditions: The solubility can depend significantly on the pH of the solution, with lower pH levels often enhancing solubility due to protonation of the amine group.
  • Temperature Influence: Increased temperature generally leads to higher solubility, allowing for more effective formulation and use in complex mixtures.

In conclusion, the solubility characteristics of this compound, especially in the context of its hydrochloride form, suggest significant utility in various chemical environments and potential roles in drug formulation where dissolution kinetics are essential. As stated, "Understanding solubility can unlock the full potential of a compound." Thus, optimizing conditions for solubility can lead to improved application outcomes.

Interesting facts

Interesting Facts about 2-(5-Methoxy-1H-Indol-3-Yl)ethanamine Hydrochloride

2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride, often referred to as a derivative of the indole family, has captured the interest of researchers for its fascinating structure and potential biological activities. Here are some engaging insights about this compound:

  • Indole Derivative: This compound is a derivative of indole, a bicyclic structure that is foundational in medicinal chemistry. Indolyl compounds are known for their diverse pharmacological activities.
  • Biological Interest: Compounds like this one have been studied for their potential role in neuropharmacology. Their unique structure can interact with neurotransmitter systems, making them valuable in exploring treatments for various neurological disorders.
  • Chemical Behavior: The presence of both an amine and a methoxy group in its structure may contribute to its solubility and reactivity, allowing for intriguing synthetic routes and modifications.
  • Research Applications: The compound is utilized in research concerning serotonin receptor interactions, which are pivotal for understanding mental health conditions such as depression and anxiety.
  • Synthetic Pathways: Because of its complex yet approachable synthesis, many chemists are drawn to developing novel methodologies for producing this compound, contributing to the collective understanding of indole chemistry.

In summary, 2-(5-methoxy-1H-indol-3-yl)ethanamine hydrochloride embodies a unique blend of chemical elegance and potential medicinal applications, making it a fascinating subject for both researchers and students alike. As noted by prominent chemists, "The exploration of indole derivatives continues to unveil their importance in the chemical and pharmacological landscapes."

Synonyms
5-Methoxytryptamine hydrochloride
66-83-1
Mexamine hydrochloride
O-Methylserotonin hydrochloride
5-Methoxy Tryptamine Hcl
2-(5-methoxy-1H-indol-3-yl)ethanamine hydrochloride
5-Methoxy-1H-indole-3-ethylamine hydrochloride
3-(2-Aminoethyl)-5-methoxyindole hydrochloride
1H-Indole-3-ethanamine, 5-methoxy-, monohydrochloride
5-Methoxytryptamine, HCl
17107-33-4
5-Methoxytryptamine HCl
4265IB6QEK
5-Methoxytryptamine monohydrochloride
MFCD00012684
Mexamine HCl
EINECS 200-637-6
2-(5-methoxy-1H-indol-3-yl)ethanamine;hydrochloride
UNII-4265IB6QEK
Mexamin
5-Methoxytryptamine-alpha,alpha,beta,beta-D4 hydrochloride
5 methoxytryptamine hydrochloride
5-Methoxy-1H-indole-3-ethylamine monohydrochloride
EINECS 241-177-6
5-Methoxy-1H-indole-3-ethylamine HCl
O-Methylserotonin HCl
INDOLE, 3-(2-AMINOETHYL)-5-METHOXY-, HYDROCHLORIDE
1,6-Hexanediamine, N,N'-bis(o-chlorobenzyl)-, dihydrochloride
MEXAMIN HYDROCHLORIDE
SPECTRUM2300296
2-(5-Methoxy-1H-indol-3-yl)-ethanamine hydrochloride
SCHEMBL1322980
CHEMBL1256138
DTXSID801017272
5-Methoxytryptamine (hydrochloride)
RCA52135
Tox21_500789
CCG-40083
AKOS000291500
FM25358
LP00789
O-METHYL SEROTONIN HYDROCHLORIDE
NCGC00094124-01
NCGC00094124-02
NCGC00261474-01
SY005094
TS-03225
DB-054966
O-Methylserotonin hydrochloride, crystalline
CS-0030491
EU-0100789
5-METHOXYTRYPTAMINE HYDROCHLORIDE [MI]
F13846
M 6628
M-3554
SR-01000076002
SR-01000076002-1
Q27258499
[2-(5-methoxy-1H-indol-3-yl)ethyl]amine hydrochloride
2-(5-methoxy-1H-indol-3-yl)ethan-1-amine hydrochloride
1H-INDOLE-3-ETHANAMINE, 5-METHOXY-, HYDROCHLORIDE (1:1)
3-(2-Aminoethyl)-5-methoxyindole hydrochloride;O-Methylserotonin hydrochloride
O-Methylserotonin hydrochloride; 3-(2-Aminoethyl)-5-methoxyindole hydrochloride