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5-Methoxytryptamine

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Identification
Molecular formula
C11H14N2O
CAS number
608-07-1
IUPAC name
2-(5-methoxy-1H-indol-3-yl)ethanamine
State
State

At room temperature, 5-Methoxytryptamine is in a solid state, typically appearing as a crystalline solid with a tendency to sublimate under certain conditions, depending on its purity and environmental factors.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
264.00
Boiling point (Kelvin)
537.15
General information
Molecular weight
190.25g/mol
Molar mass
190.2450g/mol
Density
1.1780g/cm3
Appearence

5-Methoxytryptamine is typically found as a crystalline solid. The compound is usually white or off-white in color. Being a tryptamine derivative, it shares structural similarities with other compounds in this class which are often noted for their bioactivity and roles in neurotransmission.

Comment on solubility

Solubility of 2-(5-methoxy-1H-indol-3-yl)ethanamine

The solubility of 2-(5-methoxy-1H-indol-3-yl)ethanamine, with the chemical formula C11H14N2O, can be influenced by several factors, including temperature, pH, and the solvent used. Generally, indole derivatives tend to exhibit varying degrees of solubility in different solvents:

  • Polar solvents: Compounds like methanol and ethanol may show a higher solubility for this compound due to the presence of an amine and a methoxy group that can engage in hydrogen bonding.
  • Non-polar solvents: Solubility in solvents like hexane or toluene is typically negligible, reflecting the polar nature of this compound.
  • Water solubility: While specific data may vary, 2-(5-methoxy-1H-indol-3-yl)ethanamine is likely to have limited solubility in water, possibly due to its relatively large organic structure.

It's important to remember that temperature generally plays a crucial role in solubility:

  • Higher temperatures can increase the solubility of many compounds, including this one.
  • Conversely, lower temperatures may reduce solubility.

In conclusion, 2-(5-methoxy-1H-indol-3-yl)ethanamine's solubility is highly dependent on the solvent choice and the environmental conditions. Understanding these factors can aid in the effective application and usage of this fascinating compound!

Interesting facts

Interesting Facts About 2-(5-methoxy-1H-indol-3-yl)ethanamine

2-(5-methoxy-1H-indol-3-yl)ethanamine, often referred to in the scientific community for its intriguing properties, presents a fascinating blend of structure and function. This compound is an analog of serotonin, a critical neurotransmitter in the human brain, and shares similarities with various psychoactive substances.

Key Features:

  • Connection to Neurotransmitters: As an indoleamine, it is structurally related to serotonin, which plays a crucial role in regulating mood, appetite, and sleep.
  • Potential for Research: The compound is of interest for its psychoactive properties and potential implications in mental health research, particularly in understanding how modifications in molecular structure can affect receptor interactions.
  • Substitution Effects: The presence of the methoxy group in its structure can significantly influence the compound's ability to interact with various biological targets, potentially enhancing its pharmacological profile.
  • Medicinal Chemistry: Compounds with similar structures have been under investigation for their therapeutic effects against depression and anxiety disorders.

Quoting a prominent chemist, “The beauty of chemistry lies in the intricate dance of atoms and their ability to create profoundly different effects with subtle changes to their structure.” This statement resonates particularly well with 2-(5-methoxy-1H-indol-3-yl)ethanamine, as it showcases how slight modifications can lead to significant biochemical implications.

Overall, 2-(5-methoxy-1H-indol-3-yl)ethanamine prompts ongoing research into its biological activities and potential therapeutic applications, marking it as a compound worthy of attention in both chemistry and neuroscience. As we advance our understanding of such molecules, we open new avenues for drug development and mental health treatment.

Synonyms
5-METHOXYTRYPTAMINE
608-07-1
Mexamine
2-(5-Methoxy-1H-indol-3-yl)ethanamine
Methoxytryptamine
3-(2-Aminoethyl)-5-methoxyindole
O-Methylserotonin
Mexamine base
1H-Indole-3-ethanamine, 5-methoxy-
Meksamin
5-Mot
5MOT
2-(5-Methoxyindol-3-yl)ethylamine
Meksamin (free base)
5-MeOT
2-(5-Methoxy-1H-Indol-3-Yl)Ethan-1-Amine
5-methoxy-1H-indole-3-ethanamine
DEACETYLMELATONIN
NSC 56422
5-MT
INDOLE, 3-(2-AMINOETHYL)-5-METHOXY-
Lopac-M-6628
o-methyl serotonin
EINECS 210-153-7
UNII-3VMW6141KC
BRN 0145587
3VMW6141KC
CHEBI:2089
MFCD00005662
NSC-56422
CHEMBL8165
METHOXYTRYPTAMINE, 5-
5-METHOXYTRYPTAMINE [MI]
DTXSID60209638
5-22-12-00018 (Beilstein Handbook Reference)
NSC56422
Ethanamine,2-(5-methoxy-3-indolyl)-
C05659
5 Methoxytryptamine
2-(5-Methoxy-1H-indol-3-yl)ethanamine (5-Methoxytryptamine)
Meksamine
SMR000112269
2-(5-Methoxy-1H-indol-3-yl)ethanamine; 5-Methoxytryptamine; Melatonin Related Compound A (USP); Melatonin Related Compound A
F5U
5-methoxy-tryptamine
5-Methoxy tryptamine
tryptamine, 5-Methoxy
Spectrum_000193
2-(5-Methoxy-1H-indol-3-yl)ethylamine
Tryptamine, 5-methoxy-
Spectrum2_001111
Spectrum4_000602
Spectrum5_001300
CBMicro_004933
Biomol-NT_000156
bmse000626
5-Methoxytryptamine, 97%
Lopac0_000789
Oprea1_086738
SCHEMBL41982
GTPL107
KBioGR_001124
KBioSS_000673
5-Methoxytryptamine (5-MT)
MLS000515795
MLS001424170
SPBio_001242
5-Methoxytryptamine, free base
BPBio1_000530
BDBM82087
KBio2_000673
KBio2_003241
KBio2_005809
DTXCID10132129
HMS1607I12
HMS2052G13
HMS2267B16
HMS3394G13
HMS3886L09
WLN: T56 BMJ D2Z GO1
ALBB-004965
BCP31118
SMSF0037571
WDA23605
5-METHOXYINDOLE-3-ETHANAMINE
BBL010667
CCG-15123
s6324
STK386888
AKOS000265074
AB00463
CB06924
CS-W015885
DS-1776
NC00364
SDCCGSBI-0004824.P004
CAS_66-83-1
NCGC00015694-01
NCGC00015694-02
NCGC00015694-03
NCGC00015694-04
NCGC00015694-05
NCGC00015694-10
NCGC00015694-11
NCGC00162256-01
NCGC00162256-02
NCGC00162256-03
AC-15796
SY035541
TS-02682
1H-Indole-3-ethanamine, 5-methoxy-(9CI)
2-(5-Methoxy-1H-indol-3-yl)ethanamine #
DB-053709
A8462
EU-0033500
M0131
NS00014828
EN300-75859
M-3550
M14131
2-(5-METHOXY-1H-INDOL-3-YL)-ETHYLAMINE
L000647
Q4352011
BRD-K30197592-001-01-5
BRD-K30197592-003-02-9
O-Methylserotonin; 3-(2-Aminoethyl)-5-methoxyindole
F0266-0466
Z336079372
2901782C-4651-419E-81A0-8179F6F3AA3E
Mexamine;2-(5-Methoxy-1H-indol-3-yl)ethanamine;3-(2-Aminoethyl)-5-methoxyindole