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Identification
Molecular formula
C10H9NO3
CAS number
487-79-6
IUPAC name
2-(5-hydroxy-1H-indol-3-yl)acetic acid
State
State

At room temperature, 2-(5-hydroxy-1H-indol-3-yl)acetic acid is in a solid state. It is generally stable and can be handled under normal conditions.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.15
Boiling point (Celsius)
433.15
Boiling point (Kelvin)
706.15
General information
Molecular weight
191.18g/mol
Molar mass
191.1840g/mol
Density
1.4200g/cm3
Appearence

2-(5-hydroxy-1H-indol-3-yl)acetic acid appears as a white or off-white crystalline powder. It has a characteristic and slightly acidic odor.

Comment on solubility

Solubility of 2-(5-hydroxy-1H-indol-3-yl)acetic acid (C10H9NO3)

The solubility of 2-(5-hydroxy-1H-indol-3-yl)acetic acid, a compound recognized for its biological significance, can be nuanced and fascinating. Understanding its solubility helps in predicting its behavior in various environments, particularly in biological systems.

Factors influencing the solubility of this compound include:

  • Polarity: The presence of hydroxyl groups (-OH) in the structure increases polarity, contributing to enhanced solubility in polar solvents like water.
  • Hydrogen bonding: The ability of the -OH groups to form hydrogen bonds with solvent molecules often facilitates dissolution.
  • pH dependence: Being an acidic compound, its solubility can vary significantly with changes in pH, as the ionization state will affect its interaction with the solvent.

In general, the solubility of 2-(5-hydroxy-1H-indol-3-yl)acetic acid is enhanced in polar solvents and may exhibit limited solubility in non-polar organic solvents. This characteristic can have profound implications for its usage in pharmacological formulations, where solubility may dictate bioavailability.

In summary, it is pivotal to consider these factors when assessing the solubility of 2-(5-hydroxy-1H-indol-3-yl)acetic acid, as they can significantly affect its applicability and functionality.

Interesting facts

Interesting Facts About 2-(5-Hydroxy-1H-Indol-3-yl)acetic Acid

2-(5-Hydroxy-1H-indol-3-yl)acetic acid, often known as indole-3-acetic acid, is an intriguing compound that belongs to the class of auxins, which are essential plant hormones. Here are some fascinating insights:

  • Plant Growth Regulator: This compound plays a crucial role in modulating plant growth. It influences various physiological processes, including cell division and elongation.
  • Natural Metabolite: It is a natural metabolite found in different plant species, serving as a vital component in their metabolic pathways.
  • Indole System: The indole ring structure, integral to this compound, is significant in biological functions. It is involved in the biosynthesis of many important biomolecules.
  • Research Applications: Scientists frequently study this compound for its potential applications in agriculture, particularly in enhancing crop productivity and resilience.
  • Phytohormonal Interactions: 2-(5-Hydroxy-1H-indol-3-yl)acetic acid does not act alone; it interacts with other hormones, creating a network of signals that determine growth responses in plants.

This compound not only underlines the complexity of plant biology but also opens up avenues for agricultural innovations. As one enthusiastic researcher once noted, "Understanding plant hormones is key to unlocking the potential of agriculture in an ever-changing climate."

Overall, 2-(5-hydroxy-1H-indol-3-yl)acetic acid exemplifies the intricate interplay between chemistry and biology, making it a compound of notable significance in both science and practical applications.

Synonyms
5-Hydroxyindole-3-acetic acid
54-16-0
2-(5-hydroxy-1H-indol-3-yl)acetic acid
5-HIAA
(5-Hydroxy-1H-indol-3-yl)acetic acid
5-Hydroxyindoleacetic acid
5-Hydroxyindolacetic acid
5-Hydroxyheteroauxin
Hydroxyindoleacetic acid
1321-73-9
1H-Indole-3-acetic acid, 5-hydroxy-
5-Oxyindoleacetic acid
5-Hydroxy-IAA
5-Hydroxyindol-3-ylacetic acid
5-Hydroxy-3-indoleacetic acid
5-Hydroxyindolylacetic acid
5-Hydroxy-1H-indole-3-acetic acid
5-Hydroxyindoleacetate
Indole-3-acetic acid, 5-hydroxy-
(5-hydroxyindol-3-yl)acetic acid
NSC 90432
CCRIS 4423
5-hydroxyindole acetic acid
EINECS 200-195-4
YHC763JY1P
MFCD00005639
BRN 0168797
CHEBI:27823
5HIAA
NSC-90432
5-22-05-00203 (Beilstein Handbook Reference)
5-Hydroxyindol-3-acetic acid
CHEMBL395915
NSC90432
INDOLEACETIC ACID, 5-HYDROXY-
5-hydroxyindole acetate
5-hydroxy-indole-3-acetic acid
Acid, Hydroxyindoleacetic
5-hydroxyindolylaceticacid
UNII-YHC763JY1P
5-HO-IAA
5 Hydroxy 3 Indoleacetic Acid
1H-Indoleacetic acid, hydroxy-
5 Hydroxyindolamine Acetic Acid
5-Hydroxyindolamine Acetic Acid
Acid, 5-Hydroxy-3-Indoleacetic
5HydroxyIAA
Acetic Acid, 5-Hydroxyindolamine
Acid, 5-Hydroxyindolamine Acetic
5-Oxyindoleacetate
5Hydroxyheteroauxin
Hydroxyindoleacetate
HID
2-(5-hydroxyindol-3-yl)acetic acid
5oxyindoleacetic acid
(5-hydroxy-1H-indol-3-yl)-acetic acid
5hydroxyindoleacetic acid
5-hydroxy-indole acetate
5Hydroxyindolylacetic acid
Lopac-H-8876
CBMicro_013565
5-Hydroxyindole-3-acetate
bmse000364
5Hydroxyindol3ylacetic acid
5-Hydroxy-3-indolylacetate
5-Hydroxyindol-3-ylacetate
5-hydroxy-Indole-3-acetate
NCIOpen2_001406
5Hydroxy1Hindole3acetic acid
Lopac0_000636
Oprea1_139007
Indole3acetic acid, 5hydroxy
MLS000859593
SCHEMBL138121
1HIndole3acetic acid, 5hydroxy
5-Hydroxy-1H-indole-3-acetate
5-Hydroxyindolyacetic Acid,(S)
5-HydroxyindolessigsA currencyure
5-hydroxyl indole-3-acetic acid
GTPL11900
DTXSID50861582
5-hydroxy-indol-3-yl-acetic acid
HMS2230M10
HMS3261P14
HMS3372G16
ALBB-006262
GCA20931
HY-W008253R
1H-Indole-3-aceticacid,5-hydroxy-
Tox21_500636
BBL012272
BDBM50458878
STK501256
AKOS003382389
CCG-221940
CS-W008253
FD13061
FH30381
HY-W008253
LP00636
SDCCGSBI-0013441.P003
NCGC00015522-01
NCGC00015522-02
NCGC00015522-03
NCGC00015522-04
NCGC00015522-07
NCGC00015522-08
NCGC00094003-01
NCGC00094003-02
NCGC00261321-01
DS-15683
Indole-3-acetic acid, 5-hydroxy-, 1H-
PD015273
SMR000326665
SY012014
(5-Hydroxy-1H-indol-3-yl)acetic acid #
5-Hydroxyindole-3-acetic acid (Standard)
DB-007055
EU-0100636
H0355
NS00014754
C05635
H 8876
EN300-7407243
2-(5-hydroxy-1H-indol-3-yl)acetic acid;5-HIAA
Q238532
SR-01000075583
SR-01000075583-1
5-Hydroxyindole-3-acetic acid, >=98% (HPLC), crystalline
74C13742-18FA-4D80-8B54-1B85D9463949