Skip to main content

cloxiquine

ADVERTISEMENT
Identification
Molecular formula
C18H18ClNO5
CAS number
130-26-7
IUPAC name
2-[(5-chloro-8-hydroxy-3-methyl-1-oxo-isochromane-7-carbonyl)amino]-3-phenyl-propanoic acid
State
State

At room temperature, cloxiquine is typically a solid due to its high melting point, which makes it stable under normal conditions.

Melting point (Celsius)
190.50
Melting point (Kelvin)
463.65
Boiling point (Celsius)
486.30
Boiling point (Kelvin)
759.45
General information
Molecular weight
315.74g/mol
Molar mass
315.7440g/mol
Density
1.3400g/cm3
Appearence

Cloxiquine primarily appears as a crystalline solid. It may exhibit various shades depending on purity and formulation but typically is off-white to a pale yellow in color.

Comment on solubility

Solubility of 2-[(5-chloro-8-hydroxy-3-methyl-1-oxo-isochromane-7-carbonyl)amino]-3-phenyl-propanoic acid

The solubility of the compound with the chemical formula C18H18ClNO5 can be characterized by a range of factors influenced by its molecular structure. Here are some key points to consider:

  • Hydrophilicity vs. Hydrophobicity: This compound contains hydrophilic groups such as the amine (-NH2) and hydroxyl (-OH) functionalities. These groups can enhance solubility in polar solvents, especially water.
  • Structural Complexity: The presence of a chlorinated isochromane and a phenyl group introduces varying levels of hydrophobic interactions, which can decrease solubility in non-polar solvents.
  • pH Sensitivity: As a carboxylic acid, the solubility of this compound is also affected by the pH of the solution. In acidic conditions, it may exist in its protonated form, which enhances solubility, while in alkaline conditions, it may present as a deprotonated anion, potentially increasing solubility further.
  • Temperature Dependency: Like many organic compounds, the solubility may vary with temperature; an increase in temperature generally increases solubility.

In summary, the solubility of this compound is intricately linked to its structure and the conditions under which it is analyzed. It is likely to exhibit good solubility in polar solvents, particularly under acidic conditions, making it a compound of significant interest in various chemical applications.

Interesting facts

Exploring 2-[(5-chloro-8-hydroxy-3-methyl-1-oxo-isochromane-7-carbonyl)amino]-3-phenyl-propanoic acid

This compound, characterized by its unique structure and complex interactions, offers fascinating insights into both organic chemistry and pharmaceutical applications. Here are some intriguing facts:

  • Bioactivity: Due to its distinct functional groups, this compound may exhibit significant biological activity. It is derived from isochromane, a class known for medicinal properties.
  • Role in Drug Design: With its features, this molecule exemplifies how structural modifications can enhance drug potency and selectivity. Researchers often explore such compounds in the quest for new therapeutic agents.
  • Research Potential: The presence of the chlorine atom and hydroxy group suggests interesting chemical reactivity, opening avenues for further investigation in synthesis and modification that could lead to novel compounds.
  • Applications: Its character as an amino acid derivative hints at possible utility in biochemistry, particularly in studying metabolic pathways and receptor interactions.

As a student or scientist examining this compound, you might find it beneficial to explore its synthesis routes and assess how each modification influences biological activity. Keeping a molecular perspective allows for deeper understanding and innovation in the fields of medicinal chemistry and pharmacology.

In summary, 2-[(5-chloro-8-hydroxy-3-methyl-1-oxo-isochromane-7-carbonyl)amino]-3-phenyl-propanoic acid serves as a prime example of the intricate relationship between molecular structure and functionality, making it an exciting compound for future studies!

Synonyms
Alanine, (-)-
1448049-50-0
((R)-5-chloro-8-hydroxy-3-(methyl-d3)-1-oxoisochromane-7-carbonyl-3-d)-L-phenylalanine
(R)N-(5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)phenylalanine
WLN: T66 BVOT & J D1 GG IVMYVQ1R & JQ
NSC201422
NSC221991
Ochratoxin A from Aspergillus ochraceus
L-Phenylalanine,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl]-, (R)-
SCHEMBL5110182
DTXSID30859321
RWQKHEORZBHNRI-UHFFFAOYSA-N
PHA15221
NSC-221991
2-[(5-Chloro-8-hydroxy-3-methyl-1-oxoisochroman-7-carbonyl)amino]-3-phenylpropionic acid
N-(5-Chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-carbonyl)phenylalanine
N-[(5-Chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromen-7-yl)carbonyl]phenylalanine #