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Tobramycin

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Identification
Molecular formula
C18H37N5O9
CAS number
32986-56-4
IUPAC name
2-[4,6-diamino-3-[[3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)tetrahydropyran-2-yl]methoxymethyl]-2-hydroxy-1,4-dimethyl-cyclohexoxy]-4,5-dimethyl-4-(methylamino)tetrahydropyran-3,5-diol
State
State

At room temperature, Tobramycin is typically in the form of a solid powder. It is often used in the form of aqueous solutions for medical purposes.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
467.52g/mol
Molar mass
467.5130g/mol
Density
1.5000g/cm3
Appearence

Tobramycin typically appears as a white to off-white powder. It is hygroscopic and can absorb moisture from the air.

Comment on solubility

Solubility of 2-[4,6-diamino-3-[[3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)tetrahydropyran-2-yl]methoxymethyl]-2-hydroxy-1,4-dimethyl-cyclohexoxy]-4,5-dimethyl-4-(methylamino)tetrahydropyran-3,5-diol (C18H37N5O9)

The solubility of 2-[4,6-diamino-3-[[3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)tetrahydropyran-2-yl]methoxymethyl]-2-hydroxy-1,4-dimethyl-cyclohexoxy]-4,5-dimethyl-4-(methylamino)tetrahydropyran-3,5-diol is influenced by several factors:

  • Polarity: This compound contains multiple hydroxy (-OH) groups and amino (-NH2) functionalities, which enhance its polarity. As a result, it is expected to be more soluble in polar solvents like water.
  • Molecular Structure: The complex nature of its structure, especially the presence of bulky substituents, can impact solubility. Smaller and more branched structures tend to have better solubility compared to larger, more extended ones.
  • Hydrophilicity: The hydroxyl groups contribute significantly to hydrophilicity, increasing solubility in aqueous solutions and potentially in alcohols.
  • Temperature: Solubility may vary with temperature; typically, increasing temperature can increase solubility for many solids.

In summary, the solubility of this intricate compound is likely to be significant in polar environments, although the precise solubility levels would require empirical data to ascertain. As a result, a comprehensive understanding of its solubility profile can provide valuable insights into its practical applications and behavior in various chemical contexts.

Interesting facts

Interesting Facts About 2-[4,6-Diamino-3-[[3-Amino-4,5-Dihydroxy-6-(1-Hydroxyethyl)Tetrahydropyran-2-Yl]Methoxymethyl]-2-Hydroxy-1,4-Dimethyl-Cyclohexoxy]-4,5-Dimethyl-4-(Methylamino)Tetrahydropyran-3,5-Diol

This intricate compound is a fascinating example of organic chemistry, combining various functional groups and structural motifs that are significant in many biological applications. Here are some key points to highlight:

  • Complex Structure: The compound showcases a highly complex structure that includes multiple amine groups, hydroxyl groups, and the characteristic tetrahydropyran ring, making it an interesting subject for synthetic organic chemistry.
  • Biological Relevance: Many derivatives of similar structured compounds are known to exhibit biological activity, particularly as pharmaceuticals. This compound may have potential applications in medicinal chemistry owing to its functional groups that are often associated with bioactivity.
  • Potential Chemical Interactions: The presence of amino and hydroxyl groups suggests that this compound is likely to interact heavily with biological macromolecules, which could include enzymes or receptors, playing roles in biochemical pathways.
  • Synthetic Challenges: The multi-step synthesis of such compounds presents a variety of synthetic challenges, including the need to control stereochemistry and functionality at various points during the synthesis process.
  • Research Opportunities: Given the structural complexity and potential bioactivity, this compound is a great candidate for further research. Investigating its properties could yield insights into new drug development!

Researchers have quoted, "In the realm of organic chemistry, the beauty of complexity often leads to discoveries of profound importance." As you explore this compound, consider the fascinating chemistry that underpins its structure and the myriad possibilities it represents for future applications.