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2-(4-Phenyl-1-piperidyl)cyclohexanol

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Identification
Molecular formula
C17H25NO
CAS number
82745-84-6
IUPAC name
2-(4-phenyl-1-piperidyl)cyclohexanol
State
State

At room temperature, 2-(4-Phenyl-1-piperidyl)cyclohexanol is generally a crystalline solid.

Melting point (Celsius)
119.00
Melting point (Kelvin)
392.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
259.39g/mol
Molar mass
259.3850g/mol
Density
1.0640g/cm3
Appearence

2-(4-Phenyl-1-piperidyl)cyclohexanol is a compound that appears as a crystalline solid. The exact characteristics such as color can vary depending on purity and specific form, but it is typically found in solid form at room temperature.

Comment on solubility

Solubility of 2-(4-phenyl-1-piperidyl)cyclohexanol (C17H25NO)

The solubility of 2-(4-phenyl-1-piperidyl)cyclohexanol, a compound with the molecular formula C17H25NO, can be influenced by several factors, primarily due to its organic structure. Given its large hydrophobic phenyl and cyclohexane components, this compound is expected to exhibit specific solubility characteristics in various solvents.

Solubility Characteristics

  • Solvent Polarity: In general, non-polar solvents like hexane or toluene are likely to dissolve this compound better than polar solvents such as water, due to its hydrophobic parts.
  • Hydrogen Bonding: The presence of the nitrogen atom in the piperidine ring may allow for some hydrogen bonding interaction in polar solvents, but the overall hydrophobic nature could limit the extent of this solubility.
  • Temperature Effects: Increased temperature can enhance solubility in organic solvents, making it more soluble compared to its behavior at lower temperatures.

In summary, 2-(4-phenyl-1-piperidyl)cyclohexanol is likely to have limited solubility in water due to its non-polar characteristics, while showing better solubility in organic solvents. Its solubility can be influenced by the polarity of the solvent used, temperature, and potential interactions due to its functional groups.

Interesting facts

Interesting Facts about 2-(4-Phenyl-1-piperidyl)cyclohexanol

2-(4-Phenyl-1-piperidyl)cyclohexanol, often referred to in research as a piperidine derivative, has garnered attention for its structure and potential pharmacological properties. Here are some intriguing aspects of this compound:

  • Structural Diversity: The compound features a cyclohexane ring, which contributes to its three-dimensional molecular structure, allowing it to interact uniquely with biological systems. The presence of the phenyl group enhances its ability to engage with various receptors.
  • Potential Pharmacological Applications: Research has suggested that derivatives of piperidine, like this compound, may possess antidepressant or anxiolytic properties, providing possibilities for the development of new therapeutic agents.
  • Receptor Interaction: Its structure enables it to target specific neurotransmitter receptors in the brain, which could aid in the modulation of mood and anxiety levels. This has made it a compound of interest in neuropharmacology.
  • Research Interest: Studying such compounds can lead to a better understanding of the mechanism of action for various psychiatric medications, emphasizing the role of molecular structure in drug efficacy.

In summary, 2-(4-Phenyl-1-piperidyl)cyclohexanol represents a fascinating area of study within medicinal chemistry, where tweaking molecular structures can significantly influence biological activities. As we delve deeper into the world of chemical compounds, the unique characteristics of derivatives like this one continue to inspire exciting advances in pharmaceuticals.

Synonyms
vesamicol
22232-64-0
2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol
CHEMBL20943
2-(4-Phenyl-piperidin-1-yl)-cyclohexanol
MLS000554350
2-(4-Phenyl-1-piperidinyl)cyclohexanol
Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-
SMR000146667
Cyclohexanol,2-(4-phenyl-1-piperidinyl)-, hydrochloride (1:1)
V-100
Spectrum_000292
Opera_ID_322
Prestwick0_000920
Prestwick1_000920
Prestwick2_000920
Spectrum3_001861
Lopac0_001228
Oprea1_695768
Oprea1_778558
BSPBio_003302
KBioSS_000772
MLS001201728
DivK1c_000376
SCHEMBL571598
SPBio_002989
GTPL4759
(A+/-)-Vesamicol hydrochloride
KBio1_000376
KBio2_000772
KBio2_003340
KBio2_005908
KBio3_002804
CHEBI:103974
NINDS_000376
DTXSID701009898
HMS2232G09
HMS3370J19
HMS3751O05
2-(4-phenylpiperidino) cyclohexanol
BDBM50018078
STK700544
AKOS000572998
AKOS025245452
CCG-205302
SDCCGSBI-0051195.P004
2-(4-phenylpiperidin-1-yl)cyclohexanol
IDI1_000376
NCGC00016080-02
NCGC00016080-03
NCGC00162371-01
SBI-0051195.P003
AG-205/04770017
Q7923143
BRD-A76904477-003-02-5
BRD-A76904477-003-05-8
2-(4-Phenyl-piperidin-1-yl)-cyclohexanol([3H]-(-)Vesamicol)