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2-[(4-methoxyphenyl)sulfonyl-(1-methylbutyl)amino]ethanehydroxamic acid

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Identification
Molecular formula
C14H21NO5S
CAS number
180977-50-4
IUPAC name
2-[(4-methoxyphenyl)sulfonyl-(1-methylbutyl)amino]ethanehydroxamic acid
State
State

At room temperature, it is a solid.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.10
Boiling point (Celsius)
465.20
Boiling point (Kelvin)
738.30
General information
Molecular weight
332.40g/mol
Molar mass
332.4000g/mol
Density
1.1820g/cm3
Appearence

The compound is typically a solid at room temperature. It can appear as a crystalline powder, which can vary in color, often appearing white to off-white.

Comment on solubility

Solubility of 2-[(4-methoxyphenyl)sulfonyl-(1-methylbutyl)amino]ethanehydroxamic acid

The solubility of 2-[(4-methoxyphenyl)sulfonyl-(1-methylbutyl)amino]ethanehydroxamic acid (C14H21NO5S) is influenced by its unique chemical structure, which combines a hydroxamic acid moiety with aromatic and aliphatic components. Understanding its solubility profile is crucial for applications in pharmaceutical formulations and chemical processes.

Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups such as hydroxamic acid can enhance solubility in polar solvents like water.
  • Aromatic interactions: The methoxyphenyl group can contribute to solubility in organic solvents, indicating potential compatibility with various organic solvents.
  • Aliphatic chain: The 1-methylbutyl group may increase hydrophobic interactions, which can modulate solubility depending on the solvent environment.

In general, compounds like this one that contain both polar and non-polar functional groups often exhibit amphiphilic behavior, making them partially soluble in a variety of solvents. This dual nature allows for better interaction with both aqueous and organic media, making the solubility behavior more complex.

Experimental considerations: To assess the solubility accurately, it is essential to test the compound in:

  1. Aqueous solutions
  2. Various organic solvents, such as ethanol, methanol, and DMSO

Ultimately, the solubility profile of this compound will guide researchers and formulators in its effective application across different domains.

Interesting facts

Interesting Facts about 2-[(4-methoxyphenyl)sulfonyl-(1-methylbutyl)amino]ethanehydroxamic acid

2-[(4-methoxyphenyl)sulfonyl-(1-methylbutyl)amino]ethanehydroxamic acid, often referred to in shortened terms, is a fascinating compound in the realm of medicinal chemistry. This compound is significant due to its unique structure that combines various functional groups, making it a potential candidate for pharmaceutical applications.

Key Properties and Applications

  • Bioactivity: The sulfonamide and hydroxamic acid functional groups contribute to the compound's bioactivity, potentially influencing various biological pathways.
  • Enzyme Inhibition: Compounds with hydroxamic acid moieties are often known for their ability to inhibit metalloproteases and can play a role in treating diseases related to tissue remodeling.
  • Structural Diversity: The presence of a methoxyphenyl group adds an aromatic character that can enhance the compound's interaction with biological targets.

This compound epitomizes the intricate design of drugs where structural variations can lead to vastly different biological effects. By altering specific groups within its structure, scientists can tailor the compound’s properties to improve efficacy and reduce side effects.

Research Significance

Ongoing research into 2-[(4-methoxyphenyl)sulfonyl-(1-methylbutyl)amino]ethanehydroxamic acid aims to explore its full potential:

  • Studying its interactions with specific enzymes.
  • Evaluating its role in anti-inflammatory therapies.
  • Investigating its potential as a chemotherapeutic agent.

As with many synthetic compounds, understanding the interactions at the molecular level continues to drive the field of drug discovery forward, opening the door to innovative therapeutics. In the wise words of Albert Einstein, "Scientific research is one of the most exciting and rewarding adventures in life." Indeed, the journey into the depths of chemical entities like this compound is a testament to that adventure.