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Phenindione

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Identification
Molecular formula
C16H12O3
CAS number
83-12-5
IUPAC name
2-(4-methoxyphenyl)indane-1,3-dione
State
State

Phenindione is in the solid state at room temperature, appearing typically as a crystalline powder.

Melting point (Celsius)
138.00
Melting point (Kelvin)
411.15
Boiling point (Celsius)
402.00
Boiling point (Kelvin)
675.15
General information
Molecular weight
244.27g/mol
Molar mass
222.2280g/mol
Density
1.3400g/cm3
Appearence

Phenindione is generally a yellowish crystalline powder. It has a distinctive crystalline structure that can reflect light, giving it a shiny appearance under certain conditions.

Comment on solubility

Solubility of 2-(4-methoxyphenyl)indane-1,3-dione (C16H12O3)

2-(4-methoxyphenyl)indane-1,3-dione, known for its unique structural features, presents interesting aspects regarding its solubility. Understanding the solubility of this compound can be crucial for its applications in various fields.

Solubility Characteristics

  • Organic Solvents: The compound is expected to exhibit good solubility in organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO) due to its hydrophobic nature.
  • Aqueous Solubility: However, its solubility in water is likely to be limited. This is primarily attributed to the bulky aromatic rings that hinder interactions with water molecules.
  • Temperature Dependency: Solubility may also vary with temperature; generally, increasing temperature could enhance solubility in organic solvents.

In general, when assessing the solubility of 2-(4-methoxyphenyl)indane-1,3-dione, consider the following key points:

  1. The compound favors non-polar environments.
  2. Utilizing cocktails of solvents may improve overall solubility.
  3. Be mindful of the potential for variable solubility depending on purity and presence of impurities.

In summary, 2-(4-methoxyphenyl)indane-1,3-dione showcases solubility that is predominantly governed by both its molecular structure and the nature of the solvent used.

Interesting facts

Interesting Facts about 2-(4-Methoxyphenyl)indane-1,3-dione

2-(4-Methoxyphenyl)indane-1,3-dione, a compound known for its intriguing structure and potential applications, has piqued the interest of chemists and researchers alike. This compound is notable for several reasons:

  • Unique Structure: The presence of the indane ring fused with a dione functionality contributes to its chemical reactivity and photophysical properties.
  • Potential Biological Activity: Compounds with similar structures have been investigated for their pharmacological properties, with some exhibiting anti-cancer, anti-inflammatory, and antioxidant activities.
  • Diverse Applications: Its derivatives might find applications in various fields including medicine, materials science, and organic synthesis. The methoxy group at the para position enhances electron-donating properties, possibly improving reactivity.
  • Synthetic Route: The synthesis of 2-(4-Methoxyphenyl)indane-1,3-dione offers a practical experience in organic chemistry, allowing students to explore multi-step synthesis and the importance of protecting groups.
  • Research Interest: Its structural characteristics make it a subject of interest for studies in charge transfer complexes and as a precursor for complex organic materials.

In the words of eminent chemists: "The beauty of a molecule lies not just in its structure, but also in its potential to transform our understanding of chemical processes." As research expands, the utility of 2-(4-Methoxyphenyl)indane-1,3-dione continues to be a fertile ground for innovation, making it a compound worth keeping an eye on in future scientific studies.

Synonyms
anisindione
117-37-3
Miradon
2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione
Anisin indandione
Unidone
2-p-Anisyl-1,3-indandione
Andion
Anisindiona
1H-Indene-1,3(2H)-dione, 2-(4-methoxyphenyl)-
Anisindionum
2-(4-Methoxyphenyl)indan-1,3-dione
2-(p-Methoxyphenyl)indane-1,3-dione
2-para-Anisyl-1,3-indandione
2-(p-Methoxyphenyl)-1,3-indandione
2-(4-methoxyphenyl)indene-1,3-dione
SPE 2792
Anisindionum [INN-Latin]
Anisindiona [INN-Spanish]
HSDB 3205
UNII-S747T1ERAJ
EINECS 204-186-6
S747T1ERAJ
Anisindione (INN)
NSC-759629
BRN 1880681
1,3-Indandione, 2-(p-methoxyphenyl)-
1,3-Indanedione, 2-(4-methoxyphenyl)-
DTXSID3022611
CHEBI:133809
MFCD00176194
CHEMBL712
2-(4-Methoxy-phenyl)-indan-1,3-dione
MLS000554135
DTXCID102611
3-08-00-02931 (Beilstein Handbook Reference)
NSC 759629
2-(4-methoxyphenyl)-2,3-dihydro-1H-indene-1,3-dione
NCGC00094969-01
SMR000146452
ANISINDIONE [INN]
Anisindionum (INN-Latin)
Anisindiona (INN-Spanish)
ANISINDIONE (MART.)
ANISINDIONE [MART.]
CAS-117-37-3
Miradon (TN)
SR-01000642873
Anisindione [INN:BAN:NF]
UNIDIONE
Spectrum_001355
ANISINDIONE [MI]
Opera_ID_1613
Spectrum2_000427
Spectrum3_001525
Spectrum4_000723
Spectrum5_000960
ANISINDIONE [HSDB]
ANISINDIONE [VANDF]
Oprea1_729452
SCHEMBL49379
ANISINDIONE [WHO-DD]
BSPBio_002910
KBioGR_000986
KBioSS_001835
MLS001201835
DivK1c_000336
SPECTRUM1502198
2-[4-(methyloxy)phenyl]-1H-indene-1,3(2H)-dione
SPBio_000414
GTPL6960
HMS501A18
KBio1_000336
KBio2_001835
KBio2_004403
KBio2_006971
KBio3_002410
ANISINDIONE [ORANGE BOOK]
NINDS_000336
HMS1921L18
HMS2092F04
HMS2231B10
HMS3369M11
Pharmakon1600-01502198
HY-B0924
Isopropyl N-Acetyl-?-D-glucosamine
Tox21_111370
BDBM50280155
CCG-40244
NSC759629
STK363125
AKOS000987728
Tox21_111370_1
DB01125
IDI1_000336
1,3-Indandione, 2-(4-methoxyphenyl)-
NCGC00094969-02
NCGC00094969-03
NCGC00094969-05
BS-52012
SY257597
SBI-0051739.P002
DB-041366
NS00023783
SW220113-1
D07457
E77875
AB00052289_10
AB00052289_11
EN300-7478363
Q3617574
SR-01000642873-1
SR-01000642873-3
SR-01000642873-4
BRD-K47458712-001-17-3
BRD-K47458712-001-18-1
BRD-K47458712-001-19-9
BRD-K47458712-001-20-7
BRD-K47458712-001-21-5
Z56175413
204-186-6