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4-Hydroxyphenylpyruvate

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Identification
Molecular formula
C9H8O4
CAS number
156-39-8
IUPAC name
2-(4-hydroxyphenyl)-2-oxo-acetic acid
State
State

At room temperature, 4-Hydroxyphenylpyruvate is typically a solid.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.00
Boiling point (Celsius)
327.85
Boiling point (Kelvin)
600.85
General information
Molecular weight
180.16g/mol
Molar mass
180.1570g/mol
Density
1.4250g/cm3
Appearence

4-Hydroxyphenylpyruvate appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(4-hydroxyphenyl)-2-oxo-acetic acid (C9H8O4)

The solubility of 2-(4-hydroxyphenyl)-2-oxo-acetic acid is an intriguing aspect of its chemical behavior. This compound, with a chemical formula of C9H8O4, demonstrates a notable level of solubility in various solvents:

  • Aqueous Solutions: This compound is typically soluble in water due to its ability to form hydrogen bonds with water molecules, which is facilitated by the hydroxyl (-OH) group present in its structure.
  • Organic Solvents: It is also soluble in polar organic solvents such as ethanol and methanol, where the similar polar characteristics allow for effective solvation.
  • Insolubility in Non-polar Solvents: Contrarily, this compound shows negligible solubility in non-polar solvents like hexane, as the lack of polarity hinders interaction with the compound.

Interestingly, the degree of solubility can be influenced by several factors, including:

  • Temperature: Higher temperatures generally enhance solubility for most compounds.
  • pH Level: The pH of the solution can affect the ionization state of the acid, which may further impact its solubility.
  • Presence of Other Ions: The presence of other solutes in the solution can either promote or inhibit solubility through intermolecular interactions.

In summary, the solubility of 2-(4-hydroxyphenyl)-2-oxo-acetic acid is largely defined by its functional groups and their interactions with solvents, making it a compound of interest in various chemical applications.

Interesting facts

Interesting Facts about 2-(4-hydroxyphenyl)-2-oxo-acetic acid

2-(4-hydroxyphenyl)-2-oxo-acetic acid, often referred to as a derivative of *salicylic acid*, is a fascinating compound with a range of implications in both chemistry and biological systems. Here are some intriguing insights:

  • Biological Relevance: This compound exhibits anti-inflammatory properties, akin to other phenolic acids, and is studied for its potential therapeutic applications in reducing inflammation and managing pain.
  • Precursor to Natural Products: It serves as a precursor in the biosynthesis of various natural products, displaying its significance in organic synthesis and natural compound research.
  • Analytical Chemistry: The compound is often utilized in analytical chemistry for developing new methodologies for detecting phenols, showcasing its importance in lab settings.
  • Research Frontiers: Current studies are exploring its effectiveness in certain cancer treatments, highlighting the potential of phenolic compounds in modern medicine.

Additionally, this compound showcases an intriguing blend of **hydrophilicity** and **lipophilicity**, which may influence its interactions within biological systems. As we delve deeper into the study of such compounds, we find that their complex structures often reveal unexpected properties and applications.

In the words of a notable chemist, "The study of organic compounds is not just about understanding their structure, but about unlocking their potential in the realms of health and technology."

Overall, 2-(4-hydroxyphenyl)-2-oxo-acetic acid represents a significant area of interest in both synthetic organic chemistry and medicinal chemistry, underlining the continuous interplay between chemical structure and function.

Synonyms
4-Hydroxyphenylglyoxylic acid
15573-67-8
2-(4-hydroxyphenyl)-2-oxoacetic acid
Pisolithin A
(4-hydroxyphenyl)(oxo)acetic acid
4-Hydroxyphenylglyoxylate
4-Hydroxyphenylglyoxylicacid
Benzeneacetic acid, 4-hydroxy-alpha-oxo-
para-Hydroxybenzoylformic acid
CHEBI:28719
4-hydroxybenzoylformate
CHEMBL129918
DTXSID40165960
MFCD13192798
p-hydroxybenzoylformic acid
4-hydroxybenzoylformic acid
SCHEMBL593133
DTXCID1088451
KXFJZKUFXHWWAJ-UHFFFAOYSA-N
4-Hydroxy-a-oxo-benzeneacetic acid
QAA57367
(4-Hydroxy-phenyl)-oxo-acetic acid
4-hydroxy-alpha-oxobenzeneacetic acid
BDBM50118093
2-(4-hydroxyphenyl)-2-oxoaceticacid
AKOS022504983
HY-W104819
AS-47881
DA-70104
CS-0157461
C03590
EN300-193397
F16678
AE-562/43460298
Q27103861
Z2472464309
842-891-6