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Salicylic acid

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Identification
Molecular formula
C7H6O3
CAS number
69-72-7
IUPAC name
2-(4-hydroxybenzoyl)benzoic acid
State
State
Salicylic acid is solid at room temperature, appearing in crystalline form.
Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
211.00
Boiling point (Kelvin)
484.15
General information
Molecular weight
138.12g/mol
Molar mass
138.1210g/mol
Density
1.4430g/cm3
Appearence

Salicylic acid appears as a white to off-white crystalline powder. It is commonly prepared as a fine and needle-like, crystalline solid.

Comment on solubility

Solubility of 2-(4-hydroxybenzoyl)benzoic acid

2-(4-hydroxybenzoyl)benzoic acid, also known as salicylic acid, presents unique solubility characteristics due to its functional groups. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is generally soluble in alcohols, such as ethanol and methanol, due to its ability to form hydrogen bonds.
  • Aqueous Solubility: Salicylic acid has limited solubility in water (approximately 0.2 g/100 mL at room temperature). Its low solubility can be attributed to the hydrophobic benzene rings overpowering the hydrophilic carboxylic acid group.
  • pH Dependence: The solubility of 2-(4-hydroxybenzoyl)benzoic acid increases in alkaline conditions. The ionization of the carboxyl group enhances its solubility as the pH rises, making it more soluble in basic media.
  • Temperature Effect: Increased temperature typically enhances the solubility of solids in liquids, so higher temperatures may improve the dissolution of this compound.

In conclusion, while 2-(4-hydroxybenzoyl)benzoic acid exhibits moderate solubility in organic solvents, its aqueous solubility is quite limited but can be improved under certain conditions. Adjusting pH and temperature can effectively enhance its dissolvability in relevant applications.

Interesting facts

Interesting Facts about 2-(4-hydroxybenzoyl)benzoic Acid

2-(4-hydroxybenzoyl)benzoic acid, often referred to in scientific literature and research, is a fascinating compound with a variety of applications and characteristics that capture the attention of chemists and students alike. Here are some intriguing facts:

  • Structural Significance: This compound is an example of a hydroxybenzoic acid, showcasing both aromatic and carboxylic acid functionality, which contributes to its unique chemical behavior and reactivity.
  • Biological Relevance: Compounds similar to 2-(4-hydroxybenzoyl)benzoic acid are often studied for their potential use in pharmaceuticals, particularly as anti-inflammatory agents.
  • Industrial Applications: The compound is utilized in various industrial processes, especially in the field of materials science where it can function as a precursor for advanced polymers.
  • Research Insights: Studies have shown that derivatives of 2-(4-hydroxybenzoyl)benzoic acid can exhibit interesting properties, such as photostability and antioxidant activity, making them valuable in cosmetic formulations.

Moreover, the presence of the *hydroxyl* group (-OH) significantly influences the acidity and reactivity of the compound, often making it a subject of discussion in organic chemistry courses. This compound serves as an excellent example of how subtle changes in molecular structure can lead to varying physical and chemical properties, reinforcing the importance of molecular design in the field of chemistry.

"Every compound has a story to tell, and the journey of 2-(4-hydroxybenzoyl)benzoic acid is just beginning!"

Synonyms
2-(4-Hydroxybenzoyl)benzoic acid
85-57-4
Hybenzoate
Phthalein acid
o-(p-Hydroxybenzoyl)benzoic acid
Benzoic acid, 2-(4-hydroxybenzoyl)-
BENZOIC ACID, o-(p-HYDROXYBENZOYL)-
2-[(4-hydroxyphenyl)carbonyl]benzoic acid
Benzoic acid, p-(p-hydroxybenzoyl)-
CHEMBL84525
U7255OO1G6
NSC-57609
NSC-122980
WLN: QVR BVR DQ
Hibenzate
2-(4-Hydroxybenzoyl)-Benzoic Acid
EINECS 201-616-4
NSC 122980
BRN 2116114
AI3-22141
2-(p-Hydroxybenzoyl)benzoic acid
MFCD00016507
HIBENZATE [INN]
SCHEMBL63564
3-10-00-04429 (Beilstein Handbook Reference)
UNII-U7255OO1G6
DTXSID0075360
2-(4-Hydroxybenzoyl)benzoicacid
NSC57609
2-(4-Hydroxy-benzoyl)-benzoic acid
AC-494
BDBM50145805
NSC122980
STK350538
AKOS000313023
CS-W021410
FH33825
PS-5274
4'-Hydroxybenzophenone-2-carboxylic acid
4'-HYDROXY-2-BENZOYLBENZOIC ACID
2-(4'-HYDROXYBENZOYL)BENZOIC ACID
NS00038987
2-(4-hydroxybenzoyl)benzoic acid, AldrichCPR
EN300-230459
F20344
SR-01000944843
SR-01000944843-1
Z276118976