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Meclofenamic acid

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Identification
Molecular formula
C14H11ClNO2
CAS number
644-62-2
IUPAC name
2-(4-chloro-3-methyl-anilino)benzoic acid
State
State

At room temperature, Meclofenamic acid is a solid substance.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
452.90
Boiling point (Kelvin)
726.05
General information
Molecular weight
296.75g/mol
Molar mass
296.7450g/mol
Density
1.4250g/cm3
Appearence

Meclofenamic acid appears as white crystals or crystalline powder.

Comment on solubility

Solubility of 2-(4-chloro-3-methyl-anilino)benzoic acid

The solubility of 2-(4-chloro-3-methyl-anilino)benzoic acid (C14H11ClNO2) can be influenced by several factors, primarily due to its functional groups and molecular structure. Understanding its solubility helps in various applications and formulations.

  • Polarity: As a carboxylic acid, 2-(4-chloro-3-methyl-anilino)benzoic acid possesses a polar functional group (-COOH), which typically increases solubility in polar solvents like water.
  • Solvation: It can participate in hydrogen bonding with water molecules, aiding its dissolution in aqueous solutions. The presence of the chloro group can enhance the solubility in some organic solvents.
  • Solvent Types: The compound shows a preference for polar solvents but may have limited solubility in non-polar solvents due to its relatively hydrophobic aromatic structure.
  • Temperature Influence: Like many solid compounds, its solubility may increase with temperature; thus, elevated temperatures may be beneficial in achieving higher dissolved concentrations.

In summary, while 2-(4-chloro-3-methyl-anilino)benzoic acid is expected to have some level of solubility in water due to its polar character, the degree will depend on the specific conditions, and it may exhibit variation in solubility profiles depending on the solvent environment. Understanding these nuances is crucial for practical applications.

Interesting facts

Interesting Facts About 2-(4-chloro-3-methyl-anilino)benzoic acid

2-(4-chloro-3-methyl-anilino)benzoic acid, commonly referred to by its IUPAC name, is a fascinating compound with diverse applications and properties. Here are some engaging facts about this compound:

  • Pharmaceutical Relevance: This compound is structurally related to various non-steroidal anti-inflammatory drugs (NSAIDs), which are widely used for the treatment of pain and inflammation. Its derivatives may exhibit similar therapeutic properties, making it a subject of interest in medicinal chemistry.
  • Chirality: The presence of different substituents around the aniline structure can lead to the formation of stereoisomers. The specific orientation of the substituents can drastically affect the biological activity and properties of the compound.
  • Environmental Impact: Chlorinated compounds, such as this one, can have significant environmental implications. Understanding their degradation pathways is crucial in addressing pollution and ensuring ecological safety.
  • Synthesis: The synthesis of this compound typically involves well-known organic reactions, such as acylation and substitution processes. This contributes to its study in organic synthesis courses, providing students with hands-on experience in manipulating functional groups.
  • Applications Beyond Medicine: Apart from its pharmaceutical uses, derivatives of this compound may also find applications in dyes, agrochemicals, and materials science, showcasing its versatility across different fields.

As a compound with both scientific and practical significance, 2-(4-chloro-3-methyl-anilino)benzoic acid exemplifies the intricate relationship between chemistry and real-world applications. As researchers delve deeper into its properties and effects, the potential for new discoveries remains vast.

Synonyms
2-[(4-chloro-3-methylphenyl)amino]benzoic acid
DTXSID0048688
DTXCID0028614
898128-45-5
NCGC00160431-01
2-((4-Chloro-3-methylphenyl)amino)benzoic acid
benzoic acid, 2-[(4-chloro-3-methylphenyl)amino]-
DivK1c_000791
SCHEMBL1649780
CHEMBL1996278
HMS502H13
KBio1_000791
NINDS_000791
2Y5E6D59T9
Tox21_113076
STK688369
AKOS005601004
IDI1_000791
NCGC00160431-02
CAS-898128-45-5