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Citrate

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Identification
Molecular formula
C6H8O7
CAS number
77-92-9
IUPAC name
2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid
State
State

Citrate is solid at room temperature and usually found in a crystalline form. It is highly soluble in water.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.20
Boiling point (Celsius)
325.10
Boiling point (Kelvin)
598.30
General information
Molecular weight
192.13g/mol
Molar mass
192.1260g/mol
Density
1.6650g/cm3
Appearence

Citrate typically appears as a white crystalline powder. It may also be available in the form of its crystalline salts, such as sodium citrate or potassium citrate, which also appear as white crystalline substances.

Comment on solubility

Solubility of 2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid

The solubility of 2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid in various solvents is an intriguing subject due to its unique structure and functional groups. Here are some key points to consider:

  • Aqueous Solubility: The presence of carboxylic acid groups in the compound indicates that it is likely to be soluble in water, especially at lower pH levels. This is due to the ability of the carboxyl (-COOH) group to engage in hydrogen bonding with water molecules.
  • Solubility in Organic Solvents: Depending on the polarity of the solvent, the solubility may vary. The compound may exhibit moderate solubility in polar organic solvents such as methanol or ethanol, but may show limited solubility in non-polar solvents.
  • Temperature Influence: Solubility can also be affected by temperature. Generally, an increase in temperature raises solubility for many organic compounds.
  • Salt Formation: The acidic properties allow for potential salt formation with bases, which could enhance solubility in certain environments.

In conclusion, the solubility of 2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid primarily depends on its functional groups, choice of solvent, and environmental conditions. As a rule of thumb, polar solvents will often provide better solubility for this compound than non-polar solvents.

Interesting facts

Interesting Facts about 2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid

2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid is a fascinating compound that showcases the intricate world of organic chemistry. Here are some intriguing aspects of this compound:

  • Unique Structure: The compound features a distinctive dioxolane ring, which plays a crucial role in its chemical behavior. This cyclic structure is known for its potential reactivity in various organic transformations.
  • Biological Significance: Compounds like this one are often investigated for their applications in pharmaceuticals. Their ability to interact with biological systems makes them of much interest in medicinal chemistry.
  • Functional Groups: With carboxymethyl and acetic acid functional groups, this compound demonstrates the versatility of organic molecules. These groups can participate in a variety of chemical reactions, including esterification and acylation.
  • Synthetic Pathways: Chemists often explore innovative synthetic methods to create such compounds, making them a subject of interest in synthetic organic chemistry laboratories.
  • Therapeutic Applications: The compound's structure suggests possible uses in drug design, where modifications could enhance bioactivity or alter pharmacokinetic properties.

“Every compound tells a story; it is up to us to decipher the narrative encoded in its molecular framework.” This sentiment rings true for the exploration of 2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid, where each characteristic adds depth to its potential applications.

With ongoing research and development, compounds like 2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid continue to reshape our understanding of chemical interactions and lead us toward novel solutions in various fields.

Synonyms
144-16-1
ANHYDROMETHYLENECITRIC ACID
5-Oxo-1,3-dioxolane-4,4-diacetic acid
1,3-Dioxolane-4,4-diacetic acid, 5-oxo-
2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid
2,2'-(5-oxo-1,3-dioxolane-4,4-diyl)diacetic acid
5-Oxo-1,3-dioxolan-4-ylidenedi(acetic acid)
NSC-68614
99197U4E9K
UNII-99197U4E9K
beta-(Hydroxymethoxy)-tricarballylic acid gamma-Lactone; Anhydromethylenecitric Acid; Methylenecitric Acid; NSC 68614
EINECS 205-618-6
starbld0026207
Anhydromethylene Citric Acid
1,4-diacetic acid, 5-oxo-
DTXSID60162592
.beta.-(Hydroxymethoxy) tricarballylic acid, .gamma.-lactone
NSC68614
MFCD19302163
NSC 68614
AKOS022505968
AS-85737
SY351097
DB-185941
NS00024678
G90846
Q27272158
2-(Hydroxymethoxy)-1,3-propanetricarboxylic acid, .gamma.-lactone
1,3-Propanetricarboxylic acid, 2-(hydroxymethoxy)-, .gamma.-lactone
2,2 inverted exclamation mark -(5-Oxo-1,3-dioxolane-4,4-diyl)diacetic Acid