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Indirubin

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Identification
Molecular formula
C16H10N2O2
CAS number
479-41-4
IUPAC name
2-(4-carbamimidoylphenyl)-1H-indole-6-carboxamidine
State
State

At room temperature, indirubin is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
290.00
Melting point (Kelvin)
563.15
Boiling point (Celsius)
552.80
Boiling point (Kelvin)
825.95
General information
Molecular weight
263.26g/mol
Molar mass
263.2980g/mol
Density
1.3800g/cm3
Appearence

Indirubin is a purple-red crystalline solid. It is known for its distinct vibrant coloration and exists as fine crystals or powder.

Comment on solubility

Solubility of 2-(4-carbamimidoylphenyl)-1H-indole-6-carboxamidine

The solubility of the compound 2-(4-carbamimidoylphenyl)-1H-indole-6-carboxamidine (C16H10N2O2) can be influenced by several factors. Here are some key points to consider:

  • Polarity: The presence of carboxamidine functional groups introduces polar characteristics, which can enhance solubility in polar solvents.
  • Hydrogen Bonding: This compound is capable of engaging in hydrogen bonding due to its amine and carboxamide groups, potentially increasing solubility in aqueous solutions.
  • Solvent Interaction: It is likely to show better solubility in dimethyl sulfoxide (DMSO) and water relative to non-polar solvents, owing to its polar functional groups.
  • Temperature Dependence: Solubility may increase with temperature, making it important to consider thermal effects in experimental applications.

In practical terms, the solubility characteristics of this compound are crucial when considering its application in biochemical contexts. As one insightful observation about compounds similar to this one states, “The balance between hydrophilic and lipophilic characteristics determines not only solubility but also bioavailability.” Therefore, understanding the solubility profile is essential for predicting the behavior of this compound in various environments.

Interesting facts

Interesting Facts about 2-(4-Carbamimidoylphenyl)-1H-indole-6-carboxamidine

This intriguing compound, known as 2-(4-carbamimidoylphenyl)-1H-indole-6-carboxamidine, is a part of the indole class of compounds, which are known for their diverse biological activities. Here are some fascinating aspects of this compound:

  • Biological Significance: Compounds containing the indole structure are often found in various natural products and have been associated with numerous pharmacological effects. They can serve as potential drug candidates in treating various diseases.
  • Multifunctional Properties: The presence of the carbamimidoyl group may enhance interactions with biological targets, potentially increasing the compound's efficacy in biological systems.
  • Research Applications: This compound is of particular interest in medicinal chemistry for its potential use in developing new therapeutic agents. Researchers are exploring its effects on different cellular pathways and its role in disease contexts.
  • Complex Structure: The unique arrangement of various functional groups allows for diverse chemical reactivity, which can lead to interesting derivatives and analogs that may have improved properties.
  • Synergistic Effects: When combined with other pharmacologically active compounds, the indole-6-carboxamidine structure may exhibit synergistic effects, enhancing overall efficacy in therapeutic applications.

As we continue to explore the vast world of chemical compounds, the evolving knowledge surrounding compounds like 2-(4-carbamimidoylphenyl)-1H-indole-6-carboxamidine highlights the importance of interdisciplinary research in advancing drug discovery and development.

Synonyms
dapi
4',6-Diamidino-2-phenylindole
47165-04-8
2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide
4',6-Diamidinophenyl-indole
2-(4-(Aminoiminomethyl)phenyl)-1H-indole-6-carboximidamide
CHEBI:51231
K9W25Z7ROH
6-AMIDINE-2-(4-AMIDINO-PHENYL)INDOLE
2-(4-carbamimidoylphenyl)-1H-indole-6-carboxamidine
1H-INDOLE-6-CARBOXIMIDAMIDE, 2-(4-(AMINOIMINOMETHYL)PHENYL)-
DATI
1H-Indole-6-carboximidamide, 2-[4-(aminoiminomethyl)phenyl]-
4',6-Diamino-2-phenylindol
CCRIS 3826
antifade
BRN 3557399
Indole-6-carboximidamide, 2-(4-(aminoiminomethyl)phenyl)-
4',6Diamidinophenylindole
MolMap_000017
UNII-K9W25Z7ROH
CHEMBL48217
SCHEMBL235865
GTPL5498
NPE759
DTXSID50963757
FWBHETKCLVMNFS-UHFFFAOYSA-N
BDBM50010058
AKOS025213592
SMP1_000093
AS-87205
Q238382
2(4(Aminoiminomethyl)phenyl)1Hindole6carboximidamide
Indole6carboximidamide, 2(4(aminoiminomethyl)phenyl)
1HIndole6carboximidamide, 2(4(aminoiminomethyl)phenyl)