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Chenodeoxycholoyl glycine

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Identification
Molecular formula
C26H43NO5
CAS number
474-25-9
IUPAC name
2-[4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetic acid
State
State

At room temperature, chenodeoxycholoyl glycine is generally in solid form, specifically as a crystalline powder.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
447.63g/mol
Molar mass
447.6280g/mol
Density
1.1500g/cm3
Appearence

Chenodeoxycholoyl glycine, commonly known as glycochenodeoxycholic acid, typically appears as a white to off-white powder.

Comment on solubility

Solubility of 2-[4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetic acid

The solubility of the compound C26H43NO5, also known as 2-[4-(3,7,12-trihydroxy-10,13,dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetic acid, can be influenced by several factors:

  • Molecular Structure: Due to the presence of multiple hydroxyl groups, this compound is likely to exhibit increased hydrophilicity, enhancing its solubility in polar solvents such as water.
  • Functional Groups: The amino and carboxylic acid groups contribute to potential solubility in water, whereas the hydrocarbon chains may lead to lipophilic characteristics, affecting solubility in non-polar solvents.
  • pH Dependency: The solubility may vary with pH, particularly due to the carboxylic acid functionality, which can deprotonate under basic conditions, further influencing its solubility.

In summary, the solubility of this compound is a result of its intricate structure that balances polar and non-polar characteristics. Its solubility profile can best be understood by considering:

  1. The influence of functional groups on solubility behavior.
  2. The solvent type used for testing solubility.
  3. The surrounding environmental factors, including temperature and pH.

Thus, "solubility is not merely a yes or no answer but rather a complex interplay of various chemical properties." Understanding these interactions is crucial for applications that utilize this compound.

Interesting facts

Interesting Facts about 2-[4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetic Acid

This compound, with its complex structure, represents an intriguing class of chemical entities known for their diverse biological activities. Here are some fascinating points about it:

  • Analogous to Natural Hormones: The compound is structurally related to steroid hormones. Its modifications make it a subject of interest for understanding hormone actions and interactions.
  • Role in Medical Research: Due to its hydroxyl groups, this compound exhibits potential as an active agent in drug development, particularly in areas such as cancer therapy and anti-inflammatory treatments.
  • In-depth Synthesis Studies: The synthesis of this compound poses significant challenges, prompting chemists to explore novel synthetic pathways, which enhances our understanding of organic synthesis and functionalization techniques.
  • Bioactivity of Hydroxy Groups: The multiple hydroxy groups present in the structure contribute to unique reactivity and solubility properties, making the compound a worthy candidate for further investigation in medicinal chemistry.
  • Potential Applications: Its potential applications span pharmacology, biochemistry, and even materials science, as researchers explore the compound for its capabilities in various innovative fields.

In summary, this complex compound combines elements of biological significance with intriguing synthetic chemistry, making it a rich topic for future exploration and discovery.

Synonyms
3beta-GlycocholicAcid
N-CHOLYLGLYCINE
MFCD00065902
Glycine, N-[(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-yl]-
SCHEMBL15195576
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oic acid N-(carboxymethyl)amide
Urosodeoxycholic Acid Impurity 11
2-[(R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanamido]acetic Acid
BCP13102
AKOS015958201
2-[4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetic acid
AS-13758
SY111643
Glycocholate; N-Choloylglycine; Cholylglycine
N-(3alpha,7alpha,12alpha-Trihydroxy-24-oxocholan-24-yl)-glycine