Interesting facts
Interesting Facts about 2-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide
This fascinating compound, known for its intricate structure, plays an important role in medicinal chemistry. Here are some intriguing aspects about it:
- Pharmaceutical Applications: This compound is classified as a drug candidate, primarily studied for its potential implications in neurological disorders and inflammatory conditions, showcasing the dynamic intersection of chemistry and medicine.
- Design Inspiration: The specific design of this compound, with its hydroxy and amino groups, is intended to enhance the drug’s affinity and selectivity towards certain biological targets, which is a key aspect of drug development.
- Synthetic Pathways: The synthesis of this compound involves several key reactions, including substitution and functional group transformations. Such reactions exemplify the creativity required in synthetic organic chemistry.
- Mechanistic Studies: Ongoing research investigates how this compound interacts at a molecular level, particularly focusing on its mechanism of action, which may provide insight into treating conditions like chronic pain or neurodegenerative diseases.
- Structure-Activity Relationship (SAR): The subtle changes in its structure can lead to significant variations in biological activity, making it a prime candidate for studying and understanding SAR in drug discovery.
In summation, the compound 2-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide is not only an example of complex organic synthesis but also serves as a promising avenue for therapeutic research. As scientists explore its potential, each discovery enhances our understanding of chemistry’s role in improving human health.
Synonyms
atenolol
29122-68-7
Tenormin
Prenormine
Blokium
Myocord
Normiten
(RS)-Atenolol
Duraatenolol
Betacard
Corotenol
Tenormine
Atehexal
Betablok
Cuxanorm
Juvental
Selobloc
Tenoblock
Antipressan
Atenblock
Farnormin
Internolol
Premorine
Vericordin
Anselol
Atcardil
Atecard
Atendol
Atereal
Evitocor
Hypoten
Ibinolo
Lotenal
Normalol
Prenolol
Stermin
Tenidon
Tenolol
Tenoprin
Tensimin
Vascoten
Wesipin
Alinor
Altol
Atenet
Ateni
Atenil
Aterol
Hipres
Noten
Oraday
Serten
Tredol
Uniloc
Xaten
Apo-Atenolol
Seles beta
Felo-Bits
Lo-ten
Atenolin
Atenomel
Blocotenol
Cardaxen
Cardiopress
Jenatenol
Panapres
Plenacor
Servitenol
Tenobloc
Aircrit
Betasyn
Ormidol
Prinorm
Unibloc
Loten
Atenol acis
Atenol Cophar
Atenol Fecofar
Atenol Heumann
Atenol Nordic
Atenol Quesada
Atenol Gador
Atenol Stada
Atenol-Mepha
Atenol-Wolff
Atenol Atid
Atenol ct
Atenol Genericon
Atenol Tika
Atenol Trom
Atenol von ct
Betatop Ge
Atenol-ratiopharm
Atenol AL
Atenol PB
Atenol GNR
Atenol MSD
Atenol NM Pharma
Atenololum
Scheinpharm Atenol
Atenol 1A pharma
2-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
Tenormine [French]
(r,s)-atenolol
Atenololum [INN-Latin]
ICI 66082
Novaten
Atcard
dl-Atenolol
2-[4-(2-Hydroxy-3-isopropylaminopropoxy)phenyl]acetamide
ICI 66,082
Tenormin (TN)
2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol
2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
ICI-66082
MFCD00057645
4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide
CCRIS 4196
60966-51-0
HSDB 6526
UNII-50VV3VW0TI
EINECS 249-451-7
EINECS 262-544-7
50VV3VW0TI
NSC-757832
BRN 2739235
CHEBI:2904
DTXSID2022628
Benzeneacetamide, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-
Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
C07AB03
2-(4-(2-Hydroxy-3-isopropylaminopropoxy)phenyl)acetamid
CHEMBL24
duratenol
2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide
MLS000069622
DTXCID202628
Acetamide, 2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)-
TENORETIC COMPONENT ATENOLOL
Atenolol [USAN:USP:INN:BAN:JAN]
NSC 757832
SMR000036768
Atenol
2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide
Atenololum (INN-Latin)
(+/-)-2-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide
Teno-basan
ATENOLOL (MART.)
ATENOLOL [MART.]
ATENOLOL (USP-RS)
ATENOLOL [USP-RS]
ATENOLOL (EP MONOGRAPH)
ATENOLOL (USP IMPURITY)
ATENOLOL [EP MONOGRAPH]
ATENOLOL [USP IMPURITY]
ATENOLOL (USP MONOGRAPH)
ATENOLOL [USP MONOGRAPH]
(+/-)-Atenolol
Neatenol
Tensotin
2-(P-(HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ACETAMIDE
Atenolol (USAN:USP:INN:BAN:JAN)
2-(P-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ACETAMIDE (RACEMATE)
SR-01000000159
1309283-25-7
atenololo
2-(4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl)acetamide
Artrenolol
2-(4-(2-Hydroxy-3-(Isopropylamino)propoxy)phenyl)ethanamide
phenyl)acetamide
2-(4-(2-hydroxy-3-((propan-2-yl)amino)propoxy)phenyl)acetamide
Atenolol [USAN:BAN:INN:JAN]
(y)-Atenolol
Atenalol (RS)
Atenolol,(S)
(?)-Atenolol
Atenolol (Standard)
(A+/-)-Atenolol
Tenoretic (Salt/Mix)
Atenolol (JAN/USP)
Spectrum_001364
ATENOLOL [HSDB]
ATENOLOL [USAN]
ATENOLOL [INN]
ATENOLOL [JAN]
ATENOLOL [MI]
ATENOLOL [VANDF]
Opera_ID_1283
Spectrum2_001411
Spectrum3_001448
Spectrum4_000435
Spectrum5_001509
ATENOLOL [WHO-DD]
ATENOLOL [WHO-IP]
A 7655
SCHEMBL4362
Lopac0_000121
Oprea1_448775
BSPBio_002915
GTPL548
KBioGR_000790
KBioSS_001844
Atenolol - Bio-X trade mark
MLS001066372
MLS001074163
MLS001304038
DivK1c_000057
SPECTRUM1501127
Atenolol (JP18/USP/INN)
SPBio_001482
ATENOLOL [ORANGE BOOK]
BDBM25753
HMS500C19
KBio1_000057
KBio2_001844
KBio2_004412
KBio2_006980
KBio3_002415
METKIMKYRPQLGS-UHFFFAOYSA-
4-[2'-Hydroxy-3'-(isopropylamino)propoxy]phenylacetamide
C07AB11
Atenolol, 1mg/ml in Acetonitrile
ATENOLOLUM [WHO-IP LATIN]
NINDS_000057
2-{4-[2-Hydroxy-3-(isopropylamino)propoxy]-phenyl}acetamide
HMS1569L13
HMS1921H09
HMS2090I19
HMS2092D19
HMS2233E06
HMS3259K08
HMS3260I04
HMS3266K13
HMS3369B14
HMS3369D20
HMS3369P20
HMS3411G21
HMS3675G21
HMS3886G03
Pharmakon1600-01501127
( inverted question mark)-Atenolol
BCP12899
JCC28325
Atenolol 1.0 mg/ml in Acetonitrile
Atenolol, >=98% (TLC), powder
Tox21_302426
Tox21_500121
(+/-)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
2-[4-({2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]acetamide
BBL009276
CCG-39010
GEO-03413
HY-17498R
NSC757832
s4817
STK528649
AKOS005111050
ATENOLOL COMPONENT OF TENORETIC
AC-8245
Atenolol, analytical reference material
DB00335
FH18009
KS-5341
LP00121
NC00548
SDCCGSBI-0050109.P004
IDI1_000057
MRF-0000571
NCGC00015007-06
NCGC00015007-07
NCGC00015007-08
NCGC00015007-09
NCGC00015007-10
NCGC00015007-11
NCGC00015007-13
NCGC00015007-24
NCGC00024566-03
NCGC00024566-04
NCGC00024566-05
NCGC00024566-06
NCGC00024566-07
NCGC00255122-01
NCGC00260806-01
BA166036
DA-61290
HY-17498
SBI-0050109.P003
CAS-29122-68-7
DB-072177
DB-079552
DB-214565
A1414
EU-0100121
NS00010385
2-(4-(2-hydroxy-3-(isopropylamino)propoxy)
BIM-0050109.0001
D00235
EN300-119532
O10469
AB00052208-13
AB00052208-15
AB00052208_16
L000116
Q411325
SR-01000000159-2
SR-01000000159-4
SR-01000000159-5
SR-01000000159-8
BRD-A20239487-001-02-5
BRD-A20239487-001-15-7
BRD-A20239487-001-24-9
BRD-A20239487-001-25-6
Atenolol, European Pharmacopoeia (EP) Reference Standard
Z1521553991
2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenylacetamide
Atenolol, United States Pharmacopeia (USP) Reference Standard
(RS)-2-{4-[2-Hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide
2-(4-((2RS)-2-Hydroxy-3-((1-methylethyl)amino)propyloxy)phenyl)acetamide
2-(4-{[(2S)-2-hydroxy-3-(propan-2-ylamino)propyl]oxy}phenyl)acetamide
Atenolol, Pharmaceutical Secondary Standard; Certified Reference Material
2-[4-({(2R)-2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]acetamide
106020-65-9
249-451-7
4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxyl]benzeneacetamide;2-[p-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide;(RS)-ateno lol;Atenolol
InChI=1/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
Solubility of 2-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide
The solubility of the compound 2-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide (C14H22N2O3) can be influenced by several factors due to its complex structure. Here are some key aspects to consider:
Overall, while anticipating high solubility in polar solvents, it is essential to consider that the solubility in non-polar solvents might be considerably lower due to the hydrophilic nature of its functional groups.
In certain applications, knowing the solubility characteristics is critical, as it affects the compound's bioavailability and overall efficacy in various formulations.