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Amiodarone

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Identification
Molecular formula
C25H29I2NO3
CAS number
1951-25-3
IUPAC name
2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium
State
State

At room temperature, amiodarone is in a solid state. It is typically handled as a powder.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.00
Boiling point (Celsius)
580.00
Boiling point (Kelvin)
853.00
General information
Molecular weight
645.32g/mol
Molar mass
645.3210g/mol
Density
1.5860g/cm3
Appearence

Amiodarone is a white crystalline powder. It is usually odorless.

Comment on solubility

Solubility of 2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium

The compound 2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium, with the chemical formula C25H29I2NO3, presents a unique challenge when it comes to solubility. Here are some key points to consider:

  • Hydrophobic Character: The presence of the bulky diiodo substituents and the butylbenzofuran moiety contributes to a pronounced hydrophobic character, making the compound less likely to dissolve in polar solvents like water.
  • Ammonium Group: The quaternary ammonium group may increase solubility in polar organic solvents, potentially allowing for solubility in solvents such as methanol or acetonitrile.
  • Temperature and pH Dependence: The solubility can also be affected by temperature and the pH of the solution, which might alter the protonation state of the ammonium group.
  • Solvent Specificity: Solubility studies are essential for determining the optimal solvents for this compound. It is recommended to test a range of solvents to identify the most suitable conditions.

As a general observation, compounds of this nature may exhibit limited solubility in water, but a comprehensive study would provide valuable insights into solvent interactions and potential applications.

Interesting facts

Interesting Facts about 2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium

This intriguing compound blends complex chemistry with potential applications in various fields. Here are some fascinating insights:

  • Functional Design: The presence of a benzofuran structure, known for its bioactivity, hints at significant pharmacological properties. Benzofurans are often studied for their roles in neuroscience and cardiovascular health.
  • Iodine's Influence: The two iodine atoms in the compound can be crucial for its reactivity and interaction with other systems. Iodinated compounds are often associated with enhanced x-ray contrast in medical imaging and potential therapeutic uses.
  • Ammonium Component: The diethylammonium part of the molecule reflects its potential as a surfactant or in drug delivery systems, as ammonium salts often have desirable solubilizing properties.
  • Potential Applications: Given its structure, this compound could be researched for utility in pharmaceuticals, particularly as a lead compound for developing new therapeutics targeting various diseases.
  • Green Chemistry: The incorporation of organic components like phenoxy and the benzofuran moiety indicates possible pathways toward sustainable synthesis methods, aligning with modern green chemistry principles.

Researchers are eager to explore the chemical interactions and potential biological activities associated with this compound, as such investigations could lead to breakthroughs in medicinal chemistry and drug development.

As the renowned scientist Marie Curie once said, "We must believe that we are gifted for something, and that this thing, at whatever cost, must be attained." In the case of compounds like this, the quest for knowledge and innovation drives us forward.

Synonyms
HMS1361O16
[2-[4-[(2-Butylbenzofuran-3-yl)carbonyl]-2,6-diiodophenoxy]ethyl]diethylaminium
135048-43-0