Folic Acid | Solubility of Things

Identification

Molecular formula

C₁₉H₁₉N₇O₆

CAS number

59-30-3

IUPAC name

2-[[4-[(2-amino-5-methanimidoyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

State

At room temperature, folic acid is in the form of a solid powder.

Melting point (Celsius)

250.00

Melting point (Kelvin)

523.00

Boiling point (Celsius)

0.00

Boiling point (Kelvin)

0.00

General information

Molecular weight

441.40g/mol

Molar mass

441.4040g/mol

Density

1.6000g/cm³

Appearence

Folic acid appears as a yellow or orange crystalline powder. It may exist in the form of needles or crystalline plates. This compound is typically tasteless and almost odorless.

Comment on solubility

Solubility of 2-[[4-[(2-amino-5-methanimidoyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

The solubility of the compound 2-[[4-[(2-amino-5-methanimidoyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid (C₁₉H₁₉N₇O₆) can be influenced by several factors:

Polarity: Given its complex structure comprising multiple functional groups, the polarity of this compound can impact its interactions with solvents.
pH Dependency: The presence of acidic and basic functional groups suggests that solubility may vary with pH, potentially enhancing solubility in acidic or alkaline conditions.
Solvent Type: It's likely to be more soluble in polar solvents such as water or methanol, but might exhibit limited solubility in nonpolar solvents.

In general, compounds with extensive hydrogen bonding and polar groups tend to show increased solubility in polar solvents. However, accurate solubility data should be experimentally determined to account for all variables that may influence solubility behavior. Understanding these factors can provide vital insights into the behavior of this compound in various environments.

Interesting facts

Interesting Facts about 2-[[4-[(2-amino-5-methanimidoyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

This compound is a fascinating example of a complex organic molecule, showcasing the intricate relationships between structure and function in biochemistry. Here are some noteworthy aspects:

Structural Complexity: The detailed architecture of this compound includes multiple functional groups, which provide various chemical reactivities and biological interactions. The interaction between the tetrahydropteridin structure and the amino groups defines its potential as a drug candidate.
Biological Relevance: Compounds like this one often play roles in biochemical pathways, particularly in the context of amino acid synthesis and metabolism. The presence of a pteridine structure suggests a possible relationship with folate metabolism, which is essential for DNA synthesis and repair.
Potential Therapeutic Applications: Given its complex nitrogen-rich structure, this molecule could be investigated for potential use in treating conditions such as cancer, where regulating metabolic pathways can lead to tumor reduction. The pteridine derivatives are known for their various biological activities, making this compound a tempting candidate for further research.
Synthetic Challenges: The synthesis of such a complex compound represents a significant challenge in organic chemistry. The formation of the multiple amide bonds and the introduction of diverse functional groups requires precise control of reaction conditions, showcasing the skill necessary in synthetic organic chemistry.
Research Interest: Ongoing studies may focus on exploring how slight modifications in structure can influence the biological activity and efficacy of this compound, leading researchers to develop analogs with improved properties.

In summary, 2-[[4-[(2-amino-5-methanimidoyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid embodies the beauty and complexity of modern organic chemistry, resulting in significant implications for both research and therapeutic applications.