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Belinostat

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Identification
Molecular formula
C15H14N2O4
CAS number
414864-00-9
IUPAC name
2-[[4-[2-(2-carboxyethylcarbamoyl)pyrrolidin-1-yl]sulfonylbenzoyl]amino]pentanedioic acid
State
State

Solid: Typically occurs as a white to off-white crystalline powder.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
318.28g/mol
Molar mass
0.0000g/mol
Density
1.6500g/cm3
Appearence

Belinostat is usually a white to off-white powder.

Comment on solubility

Solubility of 2-[[4-[2-(2-carboxyethylcarbamoyl)pyrrolidin-1-yl]sulfonylbenzoyl]amino]pentanedioic acid

The solubility of 2-[[4-[2-(2-carboxyethylcarbamoyl)pyrrolidin-1-yl]sulfonylbenzoyl]amino]pentanedioic acid (C15H14N2O4) is influenced by several factors, making it an intriguing compound for study:

  • Polarity: The presence of multiple functional groups such as carboxylic acids and sulfonyl groups contributes to the compound's overall polar nature, enhancing its solubility in polar solvents like water.
  • Hydrogen bonding: The ability to form hydrogen bonds due to the carboxyl groups can further improve solubility, particularly in aqueous environments.
  • pH dependency: The solubility of this compound may vary with changes in pH, as protonation/deprotonation of the carboxylic acid groups can affect molecular interactions.
  • Temperature: As with many compounds, increasing temperatures can lead to increased solubility, especially in solubilizing environments.

Moreover, the complex structure of this compound not only depicts potential versatility in solubility but also illustrates that its solubility can be examined contextually, affected by the solvent environment and interactions at play.

In conclusion, understanding the solubility characteristics of this compound is essential for its application in various fields, including pharmaceuticals and biochemical research.

Interesting facts

Interesting Facts about 2-[[4-[2-(2-carboxyethylcarbamoyl)pyrrolidin-1-yl]sulfonylbenzoyl]amino]pentanedioic acid

This intriguing compound stands out in the realm of medicinal chemistry, primarily for its complex structure and potential applications. Here are some captivating insights into this compound:

  • Innovative Design: The compound features a unique combination of functional groups that contribute to its biological activity, combining elements that may enhance solubility and bioavailability.
  • Pharmaceutical Potential: Due to its structure, this compound may exhibit promising properties in the design of therapeutic agents, particularly in targeting specific biological pathways.
  • Structure-Activity Relationship (SAR): The intricate arrangement of carboxy groups, aromatic systems, and pyrrolidine-based moieties makes this compound an excellent candidate for SAR studies.
  • Research Interest: Compounds like these are often subjects of intense research due to their potential in drug development, making them relevant in areas such as cancer therapy and anti-inflammatory treatments.
  • Multi-functional Roles: The amide and sulfonamide functionalities within this compound may play crucial roles in its bioactivity, possibly influencing enzyme interactions and receptor binding.
  • Analytical Chemistry: Characterizing such complex molecules poses challenges and opportunities for chemists, as advanced techniques like NMR and mass spectrometry are essential for elucidating their structures.

In summary, this compound is more than just a chemical formula; it represents a blend of rigorous scientific inquiry and the potential for real-world applications. As we continue to explore its properties, we may unlock new avenues in the pharmaceutical industry, enhancing our understanding of drug design.

Synonyms
SCHEMBL7083423