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Epigallocatechin gallate

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Identification
Molecular formula
C22H18O11
CAS number
989-51-5
IUPAC name
2-(3,4-dihydroxyphenyl)-4,5-dihydroxy-3-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]tetrahydropyran-2-yl]oxy-chromen-7-one
State
State

At room temperature, epigallocatechin gallate is in a solid state. It is typically observed as a yellowish powder. In solution, it forms clear to lightly colored liquids depending on the concentration.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
656.00
Boiling point (Kelvin)
929.15
General information
Molecular weight
458.37g/mol
Molar mass
458.3720g/mol
Density
1.8563g/cm3
Appearence

Epigallocatechin gallate (EGCG) appears as a slightly yellow powder. In its pure form, EGCG may also be described in texture as crystalline or amorphous depending on the processing form. Solutions of EGCG are generally colorless to a pale yellow, depending on concentration and the presence of impurities or degradation products.

Comment on solubility

Solubility of 2-(3,4-dihydroxyphenyl)-4,5-dihydroxy-3-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]tetrahydropyran-2-yl]oxy-chromen-7-one (C22H18O11)

The solubility of the compound 2-(3,4-dihydroxyphenyl)-4,5-dihydroxy-3-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]tetrahydropyran-2-yl]oxy-chromen-7-one is a fascinating aspect worth discussing. This compound, being polyhydroxylated, suggests a high level of polarity, which typically influences solubility characteristics. Here are some key points to consider:

  • Polarity: Due to the numerous hydroxyl (-OH) groups present in its structure, the compound is likely to exhibit high polarity, allowing it to interact favorably with polar solvents.
  • Water Solubility: The presence of multiple -OH groups could indicate substantial solubility in water, making it more soluble compared to non-polar compounds.
  • Organic Solvents: It may also have variable solubility in organic solvents, depending on their polarity. Solvents such as ethanol or methanol might facilitate dissolution, while non-polar solvents could show limited solubility.
  • Temperature Effects: The solubility of this compound could increase with temperature, as with many organic compounds, leading to higher dissolution rates in heated solvents.

In summary, the intricate hydroxyl pattern in 2-(3,4-dihydroxyphenyl)-4,5-dihydroxy-3-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]tetrahydropyran-2-yl]oxy-chromen-7-one suggests that it is likely to be highly soluble in polar solvents, particularly water, while its solubility in non-polar solvents may be quite limited. Understanding these solubility characteristics is crucial for applications in pharmaceuticals and biochemical research.

Interesting facts

Interesting Facts about 2-(3,4-dihydroxyphenyl)-4,5-dihydroxy-3-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]tetrahydropyran-2-yl]oxy-chromen-7-one

This complex organic compound is a fascinating member of the flavonoid family known for its intricate structure and potential health benefits. Flavonoids are renowned for their antioxidant properties, which help combat oxidative stress in biological systems. The compound's multifaceted structure features multiple hydroxyl (-OH) groups, contributing to its antioxidant capacity, making it an attractive area of study for both scientists and health enthusiasts alike.

Key Features:

  • Natural Sources: Compounds with similar structures are often found in various plants, particularly in fruits and vegetables, indicating their role in human nutrition and health.
  • Biological Activity: Studies suggest that flavonoids possess anti-inflammatory, antimicrobial, and anticancer properties, showcasing the significance of this compound in medicinal chemistry.
  • Chemical Complexity: The presence of multiple sugar moieties linked through glycosidic bonds highlights the compound's intricate nature, which can influence its reactivity and biological activity.
  • Potential Applications: Due to its structural similarity with known bioactive compounds, it may hold promise for drug development or as a natural supplement.

As a budding chemist, exploring such a complex compound allows for a greater understanding of how small changes in molecular structure can dramatically alter chemical behavior and biological effects. This compound epitomizes the beauty and utility of organic chemistry in life sciences. In the words of Nobel Laureate Linus Pauling, "The best way to have a good idea is to have a lot of ideas." In this sense, the study of compounds like this one fuels creativity and innovation in the pursuit of new therapeutic agents.