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Dichloroacetylpyrrolidine

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Identification
Molecular formula
C16H23Cl2N2O
CAS number
14176-44-8
IUPAC name
2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetamide
State
State

At room temperature, Dichloroacetylpyrrolidine is a solid compound.

Melting point (Celsius)
172.30
Melting point (Kelvin)
445.40
Boiling point (Celsius)
412.50
Boiling point (Kelvin)
685.70
General information
Molecular weight
368.27g/mol
Molar mass
368.3200g/mol
Density
1.2500g/cm3
Appearence

Dichloroacetylpyrrolidine typically appears as a white to slightly off-white crystalline solid. It is odorless and, when pure, it is free of any coloration or impurities.

Comment on solubility

Solubility of 2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetamide

The solubility of 2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetamide (C16H23Cl2N2O) can be influenced by various factors, including polarity and intermolecular interactions. This compound exhibits a distinctive structure with both aromatic and aliphatic groups, which tends to impart interesting solubility characteristics:

  • Polarity: The presence of chlorine atoms can increase the polarity, leading to varying solubility in polar solvents.
  • Hydrophobic Interactions: The aliphatic cyclohexyl group may contribute to hydrophobic interactions, affecting solubility in non-polar solvents.
  • Solvent Type: This compound may be more soluble in organic solvents such as ethanol or acetone, while displaying limited solubility in water due to its hydrophobic nature.
  • Temperature and pH: As with many compounds, solubility can also vary with changes in temperature or pH, potentially leading to unique solubility profiles under different conditions.

Overall, it can be concluded that the solubility of C16H23Cl2N2O may be moderate in organic solvents, while it is expected to be less soluble in polar solvents like water—you might say it falls into the category of “soluble in some, stubborn in others.”

Interesting facts

Interesting Facts about 2-(3,4-Dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetamide

This intriguing compound is often classified within the realm of synthetic pharmaceuticals, particularly known for its unique structure and potential applications. As a member of the acetamide class, it bears significance for its properties that affect the central nervous system. Here are some key points:

  • Structural Features: The compound possesses a dichlorophenyl group, which enhances its lipophilicity and can potentially influence its biological activity.
  • Pyrrolidine Ring: The inclusion of a pyrrolidine moiety contributes to the compound's ability to interact with various biological targets, making it a point of interest in medicinal chemistry.
  • Receptor Interaction: Compounds structurally similar to this one are known to interact with neurotransmitter receptors, particularly within the brain, leading to studies aimed at understanding their effects on mood and behavior.

Notably, it has been referenced in literature for its potential role in antidepressant activities, expanding the horizon for researchers seeking new pharmacological agents. The incorporation of multiple functional groups suggests that modifications to this compound may yield derivatives with enhanced efficacy or reduced side effects.

Students of chemistry might find it fascinating to explore the synthesis pathways of this compound, as well as its various isomers and analogs. As the scientific community continues to investigate compounds like this one, the prospects for developing new therapeutic agents remain promising.

In summary, 2-(3,4-Dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetamide stands as a compelling example of how complex organic compounds can lead to significant advancements in the field of pharmacology and beyond, illustrating the endless potential found within chemical research.

Synonyms
Talactoferrin Alfa
2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetamide
149341-39-9
3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide
3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)cyclohexyl)benzeneacetamide
SCHEMBL332192
CHEMBL290543
BDBM86547
CHEBI:103981
DTXSID101155047
CAS_135349
NSC_135349
L000607
BRD-A12822115-003-01-6
Q27181219
2-(3,4-dichlorophenyl)-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]acetamide
3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetamide