Interesting facts
Interesting Facts about 2-[3-(methylsulfamoylamino)-2-oxo-6-phenyl-1-pyridyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)acetamide
This compound is a striking example of modern medicinal chemistry, showcasing the synthesis of complex molecules designed for specific biological activities. Here are some engaging facts about this intriguing compound:
- Biological Activity: Compounds like this one are often developed with therapeutic potential in mind, particularly in fields such as oncology or infectious disease treatment. Researchers modify molecular structures to enhance efficacy, alter pharmacokinetics, or minimize side effects.
- Functional Groups: The presence of a sulfonamide group, alongside the pyridine and trifluoroisopropyl moieties, indicates potential interactions that could lead to unique biological responses. These groups can influence the compound's ability to bind to target proteins or enzymes, a critical factor in drug design.
- Fluorine Utility: The incorporation of trifluoromethyl groups in pharmaceuticals can improve metabolic stability. Fluorine atoms can also boost lipophilicity, which facilitates membrane permeability, allowing for better absorption in biological systems.
- Multi-Functional Synthesis: The synthetic routes to obtain such compounds often involve intricate multi-step processes that challenge chemists' skills. The ability to construct these complex molecules highlights advancements in synthetic organic chemistry.
- Structure-Activity Relationship (SAR): This compound serves as an excellent model for studying the SAR, as slight alterations in its structure can significantly impact its biological properties. Thus, scientists may conduct various experiments to determine how modifications affect its activity.
Overall, 2-[3-(methylsulfamoylamino)-2-oxo-6-phenyl-1-pyridyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)acetamide represents a fascinating intersection of chemistry and biology. Its complexity beckons researchers to delve deeper into its potential, while its unique functional groups provide insight into the innovation happening in pharmaceuticals today. As one chemist once famously noted, "The chemist's eye must seek the invisible."
Synonyms
CHEMBL279250
SCHEMBL6132131
MYFMPKCOIMRDDD-UHFFFAOYSA-N
BDBM50037342
2-Oxo-3-[[(methylamino)sulfonyl]amino]-6-phenyl-N-[1-(trifluoroacetyl)-2-methylpropyl]pyridine-1(2H)-acetamide
PD036077
1N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)-2-(3-amino-sulfonylaminomethyl-2-oxo-6-phenyl-1,2-dihydro-1-pyridinyl)acetamide
2-[3-(Methylaminosulfamide-amino)-2-oxo-6-phenyl-2H-pyridin-1-yl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)-acetamide
3-[[(methyl-amino)sulfonyl]amino]-2-oxo-6-phenyl-N-[3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl]-1(2h)-pyridineacetamide
Solubility Characteristics of the Compound
The compound 2-[3-(methylsulfamoylamino)-2-oxo-6-phenyl-1-pyridyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)acetamide, with the chemical formula C21H24F3N3O5S, presents interesting solubility properties that are influenced by its complex structure. Key factors regarding its solubility include:
To summarize, while some segments of the compound favor solubility in polar environments, the overall structure, particularly the presence of hydrophobic fluorinated groups, may create a complex balance. This leads to the conclusion that:
In practical scenarios, experimenting with various solvent systems could yield valuable insights into enhancing or inhibiting the solubility of this compound, allowing for optimized formulation in various contexts.