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BMBIC

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Identification
Molecular formula
C15H13N3O2
CAS number
43139-83-1
IUPAC name
2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide
State
State

At room temperature, BMBIC is in a solid state. Its structural stability is maintained up to its melting point, making it suitable for storage and handling as a solid compound.

Melting point (Celsius)
282.00
Melting point (Kelvin)
555.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
283.31g/mol
Molar mass
283.3060g/mol
Density
1.2680g/cm3
Appearence

BMBIC is typically a solid compound. It appears as a crystalline powder, often white to off-white in color. This appearance is typical for many benzimidazole derivatives, which are known for their solid-state at room temperature.

Comment on solubility

Solubility of 2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide (C15H13N3O2)

The solubility of 2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide is an intriguing aspect of its chemical properties. Understanding its solubility can provide insight into its potential applications and behavior in different environments.

Key Factors Influencing Solubility:

  • Polarity: The presence of functional groups such as the methoxy and carboxamide may affect the overall polarity of the compound, influencing its ability to dissolve in polar versus non-polar solvents.
  • Hydrogen Bonding: The carboxamide group can engage in hydrogen bonding, which may enhance solubility in polar solvents such as water.
  • Substituent Effects: The 3-methoxyphenyl group may introduce steric hindrance, which could impact solvation and, consequently, the solubility of the compound.

Common Solvents:

This compound is generally expected to dissolve well in:

  • Dimethyl sulfoxide (DMSO)
  • Ethanol
  • Aqueous buffer solutions

However, it is likely to have limited solubility in non-polar solvents due to its overall polarity. Therefore, a careful selection of solvents is crucial for experiments or applications involving this compound.

In summary, the solubility properties of 2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide may reveal critical insights into its behavior in biological and chemical systems, and assessing these properties is essential for its effective utilization.

Interesting facts

Interesting Facts about 2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide

2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide is a fascinating compound that showcases the diverse chemistry of benzimidazole derivatives. Below are some compelling aspects that highlight its significance in the field of chemical research:

  • Pharmacological Potential: This compound is recognized for its potential biological activity, particularly in medicinal chemistry. Studies suggest that benzimidazole derivatives may possess various pharmacological properties, including antimicrobial, antitumor, and antiviral activities.
  • Structural Diversity: The unique arrangement of functional groups in 2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide allows for diverse interactions within biological systems. The presence of both a methoxy group and carboxamide contributes to its molecular versatility.
  • Role in Drug Design: Compounds like this are often used as scaffolds in drug discovery. The benzimidazole framework provides a robust platform for the design of new therapeutics, offering opportunities for modifications that can enhance efficacy and bioavailability.
  • Research Applications: Numerous studies leverage the unique properties of this compound to explore mechanisms of action, such as how the benzimidazole core interacts with specific biological targets. This research is critical for advancing our understanding of disease processes and therapeutic interventions.
  • Versatility in Synthesis: The synthesis of benzimidazole derivatives, including this compound, can be approached through various methods, making it an exciting topic for synthetic organic chemists.

In summary, 2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide not only contributes to the richness of its structural chemistry but also serves as a valuable element in the ongoing quest for new and effective pharmaceutical agents. Its intriguing properties continue to inspire research, making it a noteworthy compound in the area of medicinal chemistry.

Synonyms
2-(3'-methoxyphenyl) benzimidazole-4-carboxamide
CHEMBL134022
BZC
2-(3-methoxyphenyl)-1H-benzimidazole-4-carboxamide
1efy
SCHEMBL4321727
2-(3-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxamide
NVVWVYYHTKCIAE-UHFFFAOYSA-N
BDBM50093373
DB04010
NS00070510
2-(3'-Methoxyphenyl)-1-H-benzimidazole-4-carboxamide
Q27094866
2-(3''-METHOXYPHENYL) BENZIMIDAZOLE-4-CARBOXAMIDE
2-(3-Methoxy-phenyl)-1H-benzoimidazole-4-carboxylic acid amide