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Tenoxicam

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Identification
Molecular formula
C13H11N3O4S2
CAS number
59804-37-4
IUPAC name
2-(3-methoxyphenyl)-1,1-dioxo-thieno[3,2-e]thiazine-6-sulfonamide
State
State

At room temperature, Tenoxicam is a solid.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.15
Boiling point (Celsius)
498.00
Boiling point (Kelvin)
771.15
General information
Molecular weight
337.38g/mol
Molar mass
337.3790g/mol
Density
1.5100g/cm3
Appearence

Tenoxicam is a yellow crystalline powder. The compound is typically odorless.

Comment on solubility

Solubility of 2-(3-methoxyphenyl)-1,1-dioxo-thieno[3,2-e]thiazine-6-sulfonamide

The solubility of 2-(3-methoxyphenyl)-1,1-dioxo-thieno[3,2-e]thiazine-6-sulfonamide (C13H11N3O4S2) can be described through several important factors:

  • Polarity: This compound features polar functional groups, particularly the sulfonamide group, which can enhance its interaction with polar solvents like water.
  • Solvent Interaction: It tends to dissolve more readily in organic solvents rather than in water, indicating a relatively low aqueous solubility.
  • pH Dependence: The solubility may vary with pH; at certain pH levels, protonation or deprotonation of the sulfonamide group could further influence solubility.
  • Crystal Structure: The crystalline nature of the compound can also affect solubility, as more crystalline structures generally exhibit lower solubility.

As a result, the solubility of this compound could be characterized as moderate in organic solvents but potentially limited in aqueous solutions. Understanding and analyzing the solubility is crucial for practical applications, especially in pharmacology, where bioavailability is significantly influenced by how well a compound can dissolve in biological fluids.

Interesting facts

Interesting Facts about 2-(3-methoxyphenyl)-1,1-dioxo-thieno[3,2-e]thiazine-6-sulfonamide

The compound 2-(3-methoxyphenyl)-1,1-dioxo-thieno[3,2-e]thiazine-6-sulfonamide is a fascinating example of a thienothiazine derivative. These types of compounds possess unique structural features and functionalities, making them a topic of interest in both medicinal chemistry and material science. Here are some intriguing insights:

  • Medicinal Relevance: Thienothiazine derivatives are often studied for their potential pharmaceutical applications, including antimicrobial and anti-inflammatory properties. This specific compound may exhibit similar activities due to its sulfonamide group, which is known to enhance interaction with biological targets.
  • Structural Diversity: The presence of both a thieno and a thiazine moiety contributes to its structural complexity, providing opportunities for the design of compounds with tailored properties. Such hybrid structures can result in enhanced biological activity.
  • Electron Donation: The methoxy group in the phenyl ring may influence the electron density of the compound, potentially affecting its reactivity and affinity for various biological receptors. This subtle electronic modification can significantly impact the compound's pharmacological profile.
  • Research Potential: Ongoing research into thienothiazine derivatives continues to uncover new therapeutic potentials. The unique combination of heteroatoms in this compound makes it a promising candidate for the development of novel drugs.
  • Environmental Importance: Compounds containing thiophene and thiazine rings can also play a role in the development of environmentally friendly materials, including organic semiconductors and photonic devices, paving the way for advancements in technology.

As a whole, the exploration of compounds like 2-(3-methoxyphenyl)-1,1-dioxo-thieno[3,2-e]thiazine-6-sulfonamide provides significant insight into the intersection of organic chemistry, pharmacology, and material science. Studying such compounds can yield breakthroughs not only in drug design but also in the creation of innovative materials.

Synonyms
AL6528
2-(3-methoxyphenyl)-2h-thieno-[3,2-e]-1,2-thiazine-6-sulfinamide-1,1-dioxide
2-(3-methoxyphenyl)-1,1-dioxothieno[3,2-e]thiazine-6-sulfonamide
10212-03-0
2-(3-methoxyphenyl)-1,1-dioxo-2H-1??-thieno(3,2-e)(1,2)thiazine-6-sulfonamide
2-(3-methoxyphenyl)-1,1-dioxo-2H-1??-thieno[3,2-e][1,2]thiazine-6-sulfonamide
1bn3
AL6
BDBM11938
DB04371
2-(3-methoxyphenyl)-2h-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
NS00069452
Q27095172
2-(3-methoxyphenyl)-1,1-dioxo-2H-1$l^{6},7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide