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Indigo carmine

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Identification
Molecular formula
C16H8N2O8S2
CAS number
860-22-0
IUPAC name
2-(3-hydroxy-5-sulfo-1H-indol-2-yl)-3-oxo-indole-5-sulfonic acid
State
State

Indigo carmine is typically in a solid state at room temperature, appearing as blue powder or crystals.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
466.35g/mol
Molar mass
466.3540g/mol
Density
2.0200g/cm3
Appearence

Indigo carmine typically appears as a dark blue powder or crystalline solid. It is known for its striking deep blue color, which is used in various applications including as a dye and pH indicator.

Comment on solubility

Solubility of 2-(3-hydroxy-5-sulfo-1H-indol-2-yl)-3-oxo-indole-5-sulfonic acid

The solubility of 2-(3-hydroxy-5-sulfo-1H-indol-2-yl)-3-oxo-indole-5-sulfonic acid, with the chemical formula C16H8N2O8S2, can be characterized by several important factors:

  • Polar Functional Groups: The presence of sulfonic acid groups (-SO3H) and hydroxyl groups (-OH) contributes to its overall polar nature, which greatly enhances its solubility in water.
  • Aqueous Solubility: This compound is expected to be highly soluble in aqueous environments due to its ionic and polar characteristics.
  • Solvent Compatibility: Aside from water, it may have variable solubility in organic solvents, typically dependent on their polarity.
  • Temperature Effect: It is worth noting that solubility can be influenced by temperature; generally, solubility increases with rising temperature for solid compounds.

In conclusion, due to its complex structure comprising multiple functional groups, 2-(3-hydroxy-5-sulfo-1H-indol-2-yl)-3-oxo-indole-5-sulfonic acid showcases a significant degree of solubility in polar solvents, particularly water. Thus, researchers and practitioners should consider this property when utilizing the compound in various chemical applications and formulations.

Interesting facts

Interesting Facts about 2-(3-Hydroxy-5-sulfo-1H-indol-2-yl)-3-oxo-indole-5-sulfonic acid

2-(3-Hydroxy-5-sulfo-1H-indol-2-yl)-3-oxo-indole-5-sulfonic acid, often abbreviated for convenience, is a fascinating compound in the world of organic chemistry and biochemistry. It belongs to the class of compounds known as indole derivatives, which are characterized by a unique bicyclic structure that incorporates both a six-membered benzene ring and a five-membered nitrogen-containing pyrrole ring.

Here are some notable aspects of this compound:

  • Biological Significance: Indole derivatives, including this compound, have shown potential biological activities. These can include roles in signaling pathways and interactions with various receptors, making them targets for pharmaceutical research.
  • Sulfonic Acid Group: The presence of sulfonic acid groups in its structure imparts strong acidic properties and enhances solubility in water, which is often beneficial in biological systems.
  • Research Applications: This compound is of interest in analytical chemistry, particularly in studies involving spectroscopy and chromatography, due to its distinct chromophoric properties.
  • Historical Context: The indole family has been studied for decades, with roots tracing back to early organic chemistry, making it a classic example of how simple structures can lead to complex chemical behavior.

2-(3-Hydroxy-5-sulfo-1H-indol-2-yl)-3-oxo-indole-5-sulfonic acid exemplifies the intricate connections between chemical structure and function. As is often said in the scientific community, "The structure dictates the function." This compound highlights how modifications to the indole backbone can significantly alter its properties and applications.

In summary, this compound not only plays a pivotal role in fundamental research but also embodies the ongoing quest to understand and harness the diverse functionalities of organic molecules in the realm of science.

Synonyms
INDIGOTINDISULFONIC ACID
Indigotindisulfonate
Saxon blue
Blue X
5,5'-Indigotindisulfonic acid
483-20-5
Indigo carmine acid
2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid
Indigotin I
indigo carmine free acid
Soluble Indigo Blue
X7OI7JF73P
indigo-5,5'-disulfonic acid
DTXSID0044288
CHEBI:90117
NSC-8646
Indigo Carmine Disodium Salt
Indigotine
Sachsischblau
Murabba
Indigotine Lake
Soluble Indigo
Indocarmine F
Indigotine B
Indigotine I
Indigotine N
Intense Blue
Indigotine IA
NCGC00159432-02
NCGC00159432-03
Cilefa Blue R
Indigo Carmine A
Indigo Carmine X
Grape Blue A
Airedale Blue IN
Acid Blue W
HD Indigo Carmine
Indigo Carmine AC
Indigo Carmine BP
2-(3-hydroxy-5-sulfo-1H-indol-2-yl)-3-oxoindole-5-sulfonic acid
Food Blue 2
Indigotine Blue LZ
Atul Indigo Carmine
Bucacid indigotine B
Grape Blue A Geigy
Maple Indigo Carmine
Edicol Supra Blue X
Indigocarmine [JAN]
Amacid Brilliant Blue
Indigo Carmine Powder
Mitsui Indigo Carmine
FD and C Blue 2
Aniline Carmine powder
Acid Leather Blue IC
Dolkwal Indigo Carmine
San-ei Indigo Carmine
Usacert Blue No. 2
Canacert Indigo Carmine
Hexacert Blue No. 2
Indigotine disodium salt
Indigotine Conc. Powder
Indigotine Extra Pure A
C.I. Natural Blue 2
HD Indigo Carmine Supra
Indigo Carmine Conc. FQ
A.F. Blue No. 2
Sodium indigotindisulfonate
3,3'-dioxo-[2,2'-biindolinylidene]-5,5'-disulfonic acid
1311 Blue
DTXCID601022746
L Blue Z 5010
12070 Blue
Hexacol Indigo Carmine Supra
Carmine Blue (biological stain)
Disodium indigo-5,5-disulfonate
NSC8646
Sodium 5,5'-indigotindisulfonate
CAS-483-20-5
Indigo Carmine (Biological Stain)
C.I. Food Blue 1, disodium salt
Disodium 5,5'-indigotin disulfonate
MFCD00005723
Indigo disulfonate (Biological Stain)
UNII-X7OI7JF73P
Disodium salt of 1-indigotin-S,S'-disulfonic acid
EINECS 207-593-7
Indigo blue, solubl
starbld0000901
acido indigotindisolfonico
Acido indigotindisulfonico
Acide indigotindisulfonique
Acido Indigotindisulffonico
indigo carmine (acid form)
SCHEMBL2727226
SCHEMBL2732840
SCHEMBL5455215
CHEMBL1091250
Sodium 5, 5'-indigodisulfonate
CFZXDJWFRVEWSR-UHFFFAOYSA-N
Disodium 5, 5'-indigodisulfonate
Sodium indigo-5, 5'-bisulfonate
Tox21_113169
Tox21_113170
(2E)-3-oxo-2-(3-oxo-5-sulfo-1H-indol-2-ylidene)-1H-indole-5-sulfonic acid
AKOS024386980
DB11577
NS00013528
EN300-26913798
Q27162327
3,3'-dioxo-2,2'-bis-indolyden-5,5'-disulfonic acid
(2Z)-3-oxo-2-(3-oxo-5-sulfo-indolin-2-ylidene)indoline-5-sulfonic acid
(2E)-3-Oxo-2-(3-oxo-5-sulfo-1,3-dihydro-2H-indol-2-ylidene)indoline-5-sulfonic acid
(E)-3,3'-dioxo-1H,1'H,3H,3'H-[2,2'-biindolylidene]-5,5'-disulfonic acid
{[.Delta.(sup2,2')biindoline]-5,5'-disulfonic} acid, 3,3'-dioxo-, disodium salt
{[.DELTA.2,2'-Biindoline]-5,5'-disulfonic} acid, 3, 3'-dioxo-, disodium salt
(2E)-3-oxo-2-(3-oxo-5-sulfo-1,3-dihydro-2H-indol-2-ylidene)-2,3-dihydro-1H-indole-5-sulfonic acid
1H-Indole-5-sulfonic acid, 2-(1, 3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-, disodium salt
1H-Indole-5-sulfonic acid, 2-(1, 3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidine)-2,3-dihydro-3-oxo-, disodium salt
1H-INDOLE-5-SULFONIC ACID, 2-(1,3-DIHYDRO-3-OXO-5-SULFO-2H-INDOL-2-YLIDENE)-2,3-DIHYDRO-3-OXO-