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2-(3-hydroxy-2-pyridyl)-3H-benzimidazole-5-carboxamidine

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Identification
Molecular formula
C13H11N5O
CAS number
1078-21-3
IUPAC name
2-(3-hydroxy-2-pyridyl)-3H-benzimidazole-5-carboxamidine
State
State

At room temperature, this compound exists as a crystalline solid. It is not volatile and does not sublimate easily, maintaining its solid state under standard conditions without decomposition.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.15
Boiling point (Celsius)
542.00
Boiling point (Kelvin)
815.15
General information
Molecular weight
249.27g/mol
Molar mass
249.2710g/mol
Density
1.4500g/cm3
Appearence

At room temperature, this compound is typically observed as a crystalline solid. The color can range from off-white to pale yellow, depending on purity and the presence of any impurities or degradation products. The solid form is usually dry and free-flowing.

Comment on solubility

Solubility of 2-(3-hydroxy-2-pyridyl)-3H-benzimidazole-5-carboxamidine

The solubility characteristics of 2-(3-hydroxy-2-pyridyl)-3H-benzimidazole-5-carboxamidine (C13H11N5O) are influenced by its distinctive functional groups and molecular structure. This compound, known for its complex interactions, typically exhibits a few key solubility traits:

  • Solvent Dependency: The solubility can significantly vary depending on the solvent used. For instance, it is often more soluble in polar solvents such as water and dimethyl sulfoxide (DMSO) due to its ability to form hydrogen bonds.
  • pH Influence: Like many nitrogen-containing heterocycles, the solubility of this compound can be affected by the pH of the solution. In acidic conditions, it may become more soluble.
  • Temperature Effects: Generally, as temperature increases, solubility tends to rise. Thus, heating the solution may promote greater dissolution of this compound.
  • Crystal Form: The crystalline form of the compound plays a critical role; different polymorphs can exhibit varying solubility profiles, affecting bioavailability in pharmaceuticals.

In summary, while the precise solubility can vary widely, understanding the interactions at play with the solvent and environmental conditions can provide valuable insights into the compound's potential applications and effectiveness.

Interesting facts

Interesting Facts about 2-(3-hydroxy-2-pyridyl)-3H-benzimidazole-5-carboxamidine

This fascinating compound, known as 2-(3-hydroxy-2-pyridyl)-3H-benzimidazole-5-carboxamidine, has garnered interest in various fields of chemistry and biomedicine. Here are some interesting aspects:

  • Biological Significance: The compound is recognized for its potential biological activities and has been studied for its role as a pharmacological agent. Its structure may suggest interactions with biological targets, making it a candidate for drug development.
  • Chemical Structure: The unique combination of a benzimidazole ring fused with a pyridine moiety allows this compound to exhibit diverse chemical reactivity. The hydroxyl and carboxamidine substituents enhance its capacity to participate in biological processes.
  • Research Potential: As research continues to reveal new applications, this compound might play a significant role in the development of new therapeutics, particularly in fields such as oncology or antimicrobial research.
  • Synthetic Pathways: The synthesis of 2-(3-hydroxy-2-pyridyl)-3H-benzimidazole-5-carboxamidine can be quite intricate, involving multi-step reactions that require precise control over conditions to yield the desired product.
  • Future Studies: Scientists are keen to explore its pharmacokinetics and mechanisms of action, which could uncover essential information about how compounds with similar structures interact within biological systems.

In conclusion, 2-(3-hydroxy-2-pyridyl)-3H-benzimidazole-5-carboxamidine is more than just a compound; it symbolizes the intersection of chemistry and pharmacology, promising interesting paths for future discoveries.

Synonyms
CRA_1801
2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}PYRIDIN-3-OLATE
1ghy
SCHEMBL7399288
1o32
1o33
1o34
DB03016
NS00071569
Q27456793
2-(3-hydroxypyridin-2-yl)-1H-1,3-benzodiazole-6-carboximidamide