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APDMT (Aminopropyl dimethylthiourea)

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Identification
Molecular formula
C7H17N3S
CAS number
67252-35-5
IUPAC name
2-[3-(dimethylamino)propyl]isothiourea
State
State

At room temperature, 2-[3-(dimethylamino)propyl]isothiourea is a solid. It is commonly available as a crystalline powder and should be stored in a dry, cool place to prevent it from absorbing moisture from the air.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
275.90
Boiling point (Kelvin)
549.05
General information
Molecular weight
163.30g/mol
Molar mass
163.2800g/mol
Density
1.2130g/cm3
Appearence

The compound 2-[3-(dimethylamino)propyl]isothiourea typically appears as a white to slightly off-white crystalline powder. It is hygroscopic and soluble in water and polar organic solvents.

Comment on solubility

Solubility of 2-[3-(dimethylamino)propyl]isothiourea (C7H17N3S)

The solubility of 2-[3-(dimethylamino)propyl]isothiourea in various solvents is an important aspect to consider in its applications and behavior in chemical processes. Due to the presence of the isothiourea functional group, this compound exhibits interesting solubility characteristics:

  • Polar Solvents: Generally, this compound is expected to be soluble in polar solvents such as water and alcohols (e.g., ethanol, methanol). The presence of amino and thiourea groups increases its affinity for polar environments.
  • Non-Polar Solvents: Conversely, it is likely to have limited solubility in non-polar solvents like hexane or benzene, as the molecular structure does not favor hydrophobic interactions.
  • Concentration Effects: The solubility may also depend on concentration and temperature; higher temperatures typically increase solubility in many cases.
  • pH Sensitivity: The solubility profile may be affected by pH, as protonation of the amino group could lead to enhanced solubility in acidic conditions.

In summary, the solubility behavior of 2-[3-(dimethylamino)propyl]isothiourea can be described as:

  1. Readily soluble in polar solvents.
  2. Poorly soluble in non-polar solvents.
  3. Influenced by temperature and pH conditions.

Understanding these solubility characteristics is critical for its practical applications and effectiveness in various chemical reactions.

Interesting facts

Interesting Facts about 2-[3-(dimethylamino)propyl]isothiourea

2-[3-(dimethylamino)propyl]isothiourea is a fascinating compound that has garnered attention in the chemical and pharmaceutical fields due to its unique structure and potential applications. Here are some interesting facts about this compound:

  • Versatile Applications: This compound is known for its role in biochemical research, particularly in the development of pharmaceuticals and agrochemicals. Its ability to act as a building block in organic synthesis makes it invaluable for drug development.
  • Biological Significance: The compound exhibits properties that can affect biological pathways. Research has shown its potential anti-cancer properties, attracting interest from biochemists and pharmaceutical scientists alike.
  • Structural Attributes: The presence of a dimethylamino group in its structure enhances its nucleophilicity, making it a reactive agent in various chemical reactions. This feature can lead to the formation of other biologically relevant compounds.
  • Research Potential: Scientists are investigating 2-[3-(dimethylamino)propyl]isothiourea for its role in modulating specific enzyme activities, paving the way for therapeutic interventions in certain diseases.
  • Toxicological Studies: As with many isothioureas, understanding the toxicological profile of this compound is critical. Researchers are keen on elucidating both its beneficial effects and potential toxicity to ensure safety in applications.

Overall, the study of 2-[3-(dimethylamino)propyl]isothiourea opens up a plethora of opportunities in chemical and pharmaceutical research. As the scientific community continues to explore its properties and applications, this compound could potentially lead to new discoveries that contribute significantly to medicinal chemistry.

Synonyms
Dimaprit
65119-89-3
3-(dimethylamino)propyl carbamimidothioate
CARBAMIMIDOTHIOIC ACID, 3-(DIMETHYLAMINO)PROPYL ESTER
3-(dimethylamino)propyl imidothiocarbamate
CHEMBL12344
CHEBI:81389
ZZQ699148P
BRN 2350552
UNII-ZZQ699148P
Pseudourea, 2-(3-(dimethylamino)propyl)-2-thio-
Tocris-0506
Prestwick0_000983
Prestwick1_000983
Prestwick2_000983
Prestwick3_000983
BSPBio_001045
SCHEMBL379810
SPBio_002946
BPBio1_001151
GTPL1248
DTXSID0037154
BDBM22883
AKOS006280081
NCGC00016775-01
NCGC00016775-02
NCGC00016775-03
NCGC00016775-04
NCGC00024621-01
NCGC00024621-02
3-dimethylaminopropylsulfanylmethanimidamide
CAS-23256-33-9
S-[3-(N,N-dimethylamino)propyl]isothiourea
AB00514696
[3-(carbamimidoylsulfanyl)propyl]dimethylamine
C17930
AB00514696_02
AE-641/25069014
L000225
3-DIMETHYLAMINOPROPYL SULFANYLMETHANIMIDAMIDE
Q5277162
BRD-K23541596-300-04-9
BRD-K23541596-300-05-6
BRD-K23541596-300-07-2
BRD-K23541596-300-08-0