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Propofol

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Identification
Molecular formula
C12H18O
CAS number
2078-54-8
IUPAC name
2-[3-(diisopropylamino)-1-phenyl-propyl]-4-methyl-phenol
State
State

At room temperature, propofol is a colorless oil that is typically supplied in a liquid emulsion form for medical purposes. The oil form is hydrophobic and has to be emulsified in a suitable medium for administration.

Melting point (Celsius)
18.00
Melting point (Kelvin)
291.15
Boiling point (Celsius)
256.70
Boiling point (Kelvin)
529.85
General information
Molecular weight
178.27g/mol
Molar mass
178.2710g/mol
Density
1.0480g/cm3
Appearence

Propofol is an oil-in-water emulsion, which is virtually clear and slightly yellowish or colorless. The appearance may vary slightly depending on the specific formulation used in medical contexts.

Comment on solubility

Solubility of 2-[3-(diisopropylamino)-1-phenyl-propyl]-4-methyl-phenol (C12H18O)

The solubility of the compound 2-[3-(diisopropylamino)-1-phenyl-propyl]-4-methyl-phenol is influenced by several factors such as its molecular structure and the presence of functional groups. Understanding the solubility behavior of this compound provides insights into its potential applications and interactions.

Factors Affecting Solubility

  • Molecular Structure: This compound possesses both hydrophobic (non-polar) and polar characteristics due to the presence of the hydroxyl group (-OH) of the phenol, which suggests that solubility may vary depending on the solvent used.
  • Hydrophobic Interactions: The diisopropylamino group contributes to the hydrophobic nature of the compound, potentially reducing its solubility in water, while favoring solubility in organic solvents.
  • Temperature Influence: The solubility of most organic compounds, including this one, typically increases with temperature, providing an avenue for enhanced dissolution in various solvents.

In general, this compound is likely to be more soluble in non-polar organic solvents such as dichloromethane or hexane, rather than in water. The solubility profiles can be better understood through solubility tests in different solvents to ascertain practical application avenues.

For precise applications, it is crucial to conduct experimental determinations of solubility under specific conditions to better inform the use and effectiveness of this compound in various chemical processes.

Interesting facts

Interesting Facts about 2-[3-(diisopropylamino)-1-phenyl-propyl]-4-methyl-phenol

2-[3-(diisopropylamino)-1-phenyl-propyl]-4-methyl-phenol is a fascinating chemical compound with numerous attributes worth exploring. Below are some compelling facts about this complex molecule:

  • Pharmaceutical Relevance: This compound can be analyzed for its potential applications in drug development, especially within the realm of central nervous system activities due to the presence of the diisopropylamino group, which may influence receptor interactions.
  • Structurally Diverse: Having a multi-substituted structure, it showcases the importance of functional groups in determining the behavior of the compound, affecting both its chemical reactivity and biological activity.
  • Mechanism of Action: Compounds incorporating phenolic structures are often studied for their roles in antioxidant properties. This particular derivative may also reflect interesting interactions at the molecular level, which can be beneficial for pharmacological applications.
  • Chemical Stability: Investigating the stability of this compound under various conditions can lead to insights on how to design more effective therapeutic agents with improved shelf-life and efficacy.
  • Synthesis Routes: Understanding the synthetic pathways that lead to this compound can provide chemists with knowledge useful for creating similar compounds or derivatives that might enhance desired biological effects.

As a compound with a combination of both aromatic and aliphatic features, 2-[3-(diisopropylamino)-1-phenyl-propyl]-4-methyl-phenol stands out as a potential candidate for research across different fields, notably in medicinal chemistry and material sciences. The study of its properties could unlock new avenues for therapeutic innovations.

Synonyms
124936-74-9
2-(3-(Diisopropylamino)-1-phenylpropyl)-4-methylphenol
2-[3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol
2-[3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol
2,3-BIS(1-METHYLETHYL)AMINO-1-PHENYLPROPYL-4-METHYLPHENOL
Phenol, 2-[3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-
Tolterodina
Tolterodine (racemate)
C22H31NO
2-{3-[Di(propan-2-yl)amino]-1-phenylpropyl}-4-methylphenol
OOGJQPCLVADCPB-UHFFFAOYSA-N
PNU-200583 racemate; PNU 200583 racemate; PNU200583 racemate; (+/-)-Tolterodine; Racemic tolterodine
2-[3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol monohydrobromide
Spectrum_001634
Spectrum2_000526
Spectrum3_001003
Spectrum4_001131
Spectrum5_001502
BSPBio_002725
KBioGR_001641
KBioSS_002114
SCHEMBL580446
SPBio_000511
(R)-(+)-Tolterodine;(+)-Tolterodine;(R)-Tolterodine;PNU-200583
CHEMBL319757
KBio2_002114
KBio2_004682
KBio2_007250
KBio3_001945
DTXSID70861286
HMS3373N19
BCP11956
BCP24952
STL455112
AKOS016002007
SB83213
NCGC00178506-01
SBI-0206790.P001
EN300-296206
L000756
2-[3-(dipropan-2-ylamino)-1-phenylpropyl]-4-methylphenol
2-{3-[bis(propan-2-yl)amino]-1-phenylpropyl}-4-methylphenol
3-(2-hydroxy-5-methylphenyl)-N,N-diisopropyl-3-phenylpropylamine
N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropyl amine
N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropylamine
(R)-(+)-Tolterodine; (+)-Tolterodine; (R)-Tolterodine; PNU-200583;PHA-686464B