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Aminoguanidine

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Identification
Molecular formula
C8H11ClN6
CAS number
79-17-4
IUPAC name
2-(3-chlorophenyl)-1-(diaminomethylene)guanidine
State
State

At room temperature, aminoguanidine hydrochloride is typically in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
211.66g/mol
Molar mass
211.6300g/mol
Density
1.3400g/cm3
Appearence

Aminoguanidine appears as a white crystalline solid. It is often available in the form of its bicarbonate salt, which is also white and crystalline.

Comment on solubility

Solubility of 2-(3-chlorophenyl)-1-(diaminomethylene)guanidine (C8H11ClN6)

The solubility of 2-(3-chlorophenyl)-1-(diaminomethylene)guanidine is influenced by several factors including its molecular structure and interactions with solvents. Generally, this compound is characterized by the following solubility traits:

  • Polarity: The presence of amino groups (–NH2) in its structure suggests that hydrogen bonding may facilitate solubility in polar solvents such as water.
  • Chlorine Substitution: The 3-chlorophenyl group adds to the hydrophobic characteristics of the compound, which may hinder its solubility in non-polar solvents.
  • Temperature Dependency: As with many organic compounds, solubility can vary with temperature; typically, higher temperatures can enhance solubility in the appropriate solvents.

In summary, while 2-(3-chlorophenyl)-1-(diaminomethylene)guanidine is expected to be more soluble in polar solvents due to its functional groups, the overall solubility will be a balance of its hydrophobic and hydrophilic characteristics. Testing in various solvents may provide more specific insights into its solubility profile.

Interesting facts

Interesting Facts about 2-(3-chlorophenyl)-1-(diaminomethylene)guanidine

2-(3-chlorophenyl)-1-(diaminomethylene)guanidine is a fascinating compound that showcases the diverse nature of organic chemistry. Here are some intriguing points about this compound:

  • Structurally Unique: This compound features a guanidine derivative, which is significant for its reactivity and ability to form diverse chemical bonds.
  • Biological Relevance: Compounds containing the guanidine group are often associated with a variety of biological activities, including potential anti-inflammatory and anticancer properties.
  • Role of Chlorine: The presence of the chlorophenyl group, with chlorine as a substituent, can greatly influence the compound’s chemical behavior and reactivity, often enhancing its lipophilicity.
  • Synergistic Effects: This compound’s structure allows for fascinating interactions with biological molecules, making it a subject of study in pharmacology and medicinal chemistry.
  • Versatile Synthetic Pathways: The synthesis of such guanidine derivatives can be achieved through various methods, including the condensation of amines and carbonyl compounds, exemplifying the creativity in synthetic organic chemistry.

In conclusion, 2-(3-chlorophenyl)-1-(diaminomethylene)guanidine presents a rich field of study for chemists interested in its unique structure and potential applications. As one prominent scholar noted, "The study of guanidine derivatives opens doors to innovative therapeutic agents." This highlights the importance of continuing research in this area to uncover new possibilities within medicinal chemistry.

Synonyms
m-Chlorophenylbiguanide
mCPBG
1-(3-Chlorophenyl)biguanide
48144-44-1
N-(3-Chlorophenyl)imidodicarbonimidic diamide
2-(3-chlorophenyl)-1-(diaminomethylidene)guanidine
1-(m-Chlorophenyl)biguanide
N-(3-chlorophenyl)-N'-(diaminomethylene)guanidine
meta-chlorphenylbiguanide
Imidodicarbonimidic diamide, N-(3-chlorophenyl)-
M-Chlorophenylbiguanidine
3-Chloro-Phenyl biguanide
CHEMBL13790
CHEBI:32347
910A4X901V
3-chlorophenyl-biguanide
1-(m-Chlorophenyl)biguanide hydrochloride
[3H]meta-chlorophenylbiguanide
UNII-910A4X901V
N-(3-Chlorophenyl)imidodicarbonimidic diamide hydrochloride
1-carbamimidamido-N-(3-chlorophenyl)methanimidamide
Tocris-0440
Lopac-C-144
m-chloro-phenyl-biguanide
Biomol-NT_000138
1 (3 chlorophenyl)biguanide
1-(m-chlorphenyl)-biguanide
Lopac0_000343
BPBio1_000112
GTPL2287
GTPL2304
SCHEMBL1229884
SCHEMBL2144213
SCHEMBL8223193
SCHEMBL23306696
BDBM82474
DTXSID70197436
ALBB-023903
BDBM50053615
MFCD05854288
STK109167
STK663844
AKOS002224857
AKOS003345860
CCG-204438
SDCCGSBI-0050331.P002
NCGC00015188-01
NCGC00015188-02
NCGC00015188-03
NCGC00015188-04
NCGC00015188-05
NCGC00015188-06
NCGC00015188-09
NCGC00024591-01
NCGC00024591-02
NCGC00024591-03
CAS_2113-05-5
C13646
H34229
AB00691678-08
2-(3-chlorophenyl)-1-(diaminomethylene)guanidine
1-(3-chlorophenyl)-3-(diaminomethylidene)guanidine
Q5103143
BRD-K36965586-001-01-7
BRD-K36965586-003-03-9
BRD-K36965586-003-08-8
guanidine, N-(3-chlorophenyl)-N'-(diaminomethylene)-
1-{[{[AMINO(IMINO)METHYL]AMINO}(IMINO)METHYL]AMINO}-3-CHLOROBENZENE