Interesting facts
Interesting Facts about 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
This compound, often referred to in scientific literature for its medicinal properties, belongs to a class of drugs that have gained attention for potential therapeutic applications. Here are some fascinating insights:
- Pharmacological Interest: This compound exhibits a structural framework that is considered valuable in the development of neuropharmacological agents, particularly in the context of treatment for conditions like anxiety and depression.
- Multi-Target Action: The presence of the piperazine moiety is known to enhance binding to various receptors, which may account for its multi-target pharmacological action, a desirable attribute in drug design.
- Synthetic Pathways: The synthesis of this compound represents an intriguing challenge in organic chemistry, whereby chemists utilize various techniques to assemble complex molecular frameworks efficiently.
- Structure-Activity Relationship (SAR): Understanding the SAR of this compound is crucial for optimizing its efficacy and minimizing side effects. Researchers explore modifications to the triazole and pyridine rings to fine-tune its biological activity.
- In Vivo Studies: Preliminary in vivo studies are often conducted to evaluate the pharmacokinetics and pharmacodynamics of this compound, revealing its potential effectiveness and safety profile in a biological system.
Overall, the exploration of 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one presents a compelling case for the intersection of chemistry and medicine, showcasing how small molecular changes can lead to significant pharmacological implications. As scientists continue to uncover the mysteries of this compound, its future applications may influence treatments for various mental health disorders.
Synonyms
trazodone
19794-93-5
Trazodon
Beneficat
Trazalon
Trazodil
Trazodona
Trazonil
Trittico
Desirel
Sideril
Trazodonum
Trazodonum [INN-Latin]
Trazodona [INN-Spanish]
Trazodonum [Latin]
Trazodone free base
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-
UNII-YBK48BXK30
EINECS 243-317-1
YBK48BXK30
Trazodone (INN)
BRN 0628010
CHEBI:9654
1,2,4-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-
CHEMBL621
J10.767K
DTXSID5045043
Tradozone
HSDB 7048
EC 243-317-1
Trazodonum (Latin)
19794-93-5 (free)
s-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(m-chlorophenyl)-1-piperazinyl)propyl)-
Trazodona [Spanish]
TRAZODONE [INN]
Trazodonum (INN-Latin)
Trazodona (INN-Spanish)
Trazodone [INN:BAN]
2-(3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
1,2,4-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-,
2-(3-(4-(M-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-S-TRIAZOLO(4,3-A)PYRIDIN-3(2H)-ONE
2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one
Trittico (TN)
2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,5-a]pyridin-3-one
NCGC00016035-02
CAS-25332-39-2
2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)(1,2,4)triazolo(4,3-a)pyridin-3(2H)-one
2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)(1,2,4)triazolo(4,3-a)pyridin-3(2H)-one
2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Trazodone (Standard)
Spectrum_001424
TRAZODONE [MI]
Prestwick0_000292
Prestwick1_000292
Prestwick2_000292
Prestwick3_000292
Spectrum2_000854
Spectrum3_001560
Spectrum4_000755
Spectrum5_000974
Lopac-T-6154
TRAZODONE [VANDF]
TRAZODONE [WHO-DD]
Lopac0_001159
Oprea1_185901
SCHEMBL28167
BSPBio_000224
BSPBio_003040
GTPL213
KBioGR_001110
KBioSS_001904
DivK1c_000196
SPBio_000867
SPBio_002443
BPBio1_000248
HY-B0478AR
DTXCID3025043
HY-B0478A
KBio1_000196
KBio2_001904
KBio2_004472
KBio2_007040
KBio3_002540
N06AX05
NINDS_000196
BCP07176
BDBM50073444
s5857
AKOS015896423
AC-6778
CCG-205233
DB00656
SDCCGSBI-0051126.P004
2-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
IDI1_000196
NCGC00016035-01
NCGC00016035-03
NCGC00016035-04
NCGC00016035-05
NCGC00016035-06
NCGC00016035-07
NCGC00016035-08
NCGC00016035-09
NCGC00016035-10
NCGC00016035-12
NCGC00016035-25
NCGC00024405-03
8-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl]-1,7,8-triazabicyclo[4.3.0]nona-2,4,6-trien-9-one hydrochloride
DA-58707
SBI-0051126.P003
CS-0009580
NS00010404
C07156
D08626
EN300-708789
AB00053648-14
AB00053648_15
AB00053648_16
L000771
Q411457
BRD-K70778732-003-05-1
BRD-K70778732-003-15-0
BRD-K70778732-003-26-7
BRD-K70778732-003-27-5
2-(3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one #
243-317-1
Solubility of 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
The solubility of the compound 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one (C19H22ClN5O) can be influenced by several factors, including its molecular structure and the presence of functional groups. It is known that:
"Solubility behavior is essential to understanding the compound's bioavailability and potential applications." This particular compound may exhibit varying solubility profiles based on its interactions with different solvents, making it a subject of interest for various chemical analyses.