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Benazepril

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Identification
Molecular formula
C24H28N2O5
CAS number
86541-75-5
IUPAC name
2-[3-[(1-ethoxycarbonyl-3-phenyl-propyl)amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid
State
State

Benazepril is typically a solid at room temperature. It is found in tablet form for medicinal use.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
165.00
Boiling point (Kelvin)
438.15
General information
Molecular weight
460.58g/mol
Molar mass
460.5780g/mol
Density
1.2740g/cm3
Appearence

Benazepril is typically found as white to off-white crystalline powder. It is odorless or has a faint characteristic odor.

Comment on solubility

Solubility Overview of 2-[3-[(1-ethoxycarbonyl-3-phenyl-propyl)amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid

The solubility of 2-[3-[(1-ethoxycarbonyl-3-phenyl-propyl)amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid (C24H28N2O5) is an important property that can influence its applications in various fields. This compound exhibits the following solubility characteristics:

  • Solvent Compatibility: It is essential to test this compound for compatibility with different solvents. Solubility may vary in:
    • Aqueous solutions
    • Organic solvents (e.g., ethanol, acetone)
  • Influencing Factors: The solubility is often affected by:
    • Temperature: Higher temperatures typically increase solubility.
    • pH Levels: The presence of acidic or basic conditions may enhance or inhibit solubility.
    • Presence of other solutes: Certain ions or molecules can either promote or hinder solubility.
  • General Trends: Compounds with hydrophilic and hydrophobic characteristics will show solubility patterns such as:
    1. Higher solubility in polar solvents if they possess polar functional groups.
    2. Lower solubility in non-polar solvents due to molecular interactions.

In conclusion, understanding the solubility of this chemical compound is crucial for its practical use, formulation, and bioavailability. As always, specific experiments should be conducted to determine exact solubility under controlled conditions to predict its behavior in various applications effectively.

Interesting facts

Interesting Facts About 2-[3-[(1-Ethoxycarbonyl-3-phenyl-propyl)amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid

2-[3-[(1-Ethoxycarbonyl-3-phenyl-propyl)amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid is a fascinating compound that exemplifies the complexity of organic synthesis and the rich chemistry associated with benzazepines. Here are some intriguing aspects to consider:

  • Structural Diversity: The compound contains a benzazepine core, which is known for its biological activity. This makes it an interesting candidate for medicinal chemistry and pharmaceutical development.
  • Biological Relevance: Compounds with structures similar to this one are often investigated for their potential pharmacological properties. Researchers explore how modifications in the structure can impact biological activity.
  • Functional Groups: The presence of ethoxycarbonyl and amino functional groups contributes to the compound's reactivity and interaction with biological molecules. This diversity can lead to multiple reaction pathways in biological systems.
  • Research Interest: This compound has garnered attention in various studies aimed at understanding its mechanism of action. Such analyses can unveil crucial insights into how similar compounds may function as drugs.
  • Application Potential: Compounds of this class are being explored for therapeutic uses, including their possible roles in treating neurological disorders or as analgesics, showing the importance of exploring structural analogs.

In essence, 2-[3-[(1-Ethoxycarbonyl-3-phenyl-propyl)amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid serves as a reminder of the elegance and complexity found within organic chemistry. As research continues, it holds promise for new discoveries and advancements in medicinal chemistry.

Synonyms
98626-50-7
2-[3-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid
O-Ethoxy Benazeprilat
1H-1-Benzazepine-1-aceticacid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-,[R-(R*,S*)]- (9CI)
CGS14824A
3-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid
3-[[1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid
SCHEMBL678167
CHEMBL1604571
CHEBI:91547
DTXSID10861088
XPCFTKFZXHTYIP-UHFFFAOYSA-N
HMS3604E05
EBC20003
NCGC00167782-01
DB-056935
BRD-A15131297-003-01-9
Q27163380
Cyclohexanol, 5-methyl-2-(1-methylethenyl)-, acetate, (1a,2b,5a)-(+/-)-
{3-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl}acetic acid
1-carboxymethyl-3-(1-ethoxycarbonyl-3-phenylpropylamino)-2,-3,4,5-tetrahydro-1H-[1]benzazepin-2-one
1-Carboxymethyl-3-(1-ethoxycarbonyl-3-phenylpropylamino)-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one
2-(3-((1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid