Interesting facts
Interesting Facts about 2-[3-(1-cyano-1-methyl-ethyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methyl-propanenitrile
This intriguing compound is a member of the triazole family, which is known for its diverse applications in various fields, particularly in pharmaceuticals and agriculture. Its complex structure not only exhibits potential biological activity but also highlights the intricate nature of organic synthesis.
Unique Structural Features
- Triazole Ring: The presence of the 1,2,4-triazole moiety is significant due to its role in a variety of biological activities, including antifungal and antimicrobial properties.
- Cyano Group: The cyano (–CN) function contributes to the compound’s reactivity, making it a versatile intermediate in synthetic chemistry.
- Multi-functional Groups: The combination of the triazole and cyano groups alongside various alkyl chains allows for modifications that can enhance the compound's properties and efficacy.
Applications and Importance
The compound has garnered attention for several reasons:
- Pharmaceuticals: It is potentially valuable in drug development, particularly in the search for novel antifungal agents.
- Agricultural Chemicals: Its structural features suggest potential applications in agrochemicals, where similar compounds are used to protect crops from pests and diseases.
- Research Tool: The synthesis and study of such compounds can serve as an important tool in medicinal chemistry, allowing scientists to explore structure-activity relationships.
In the realm of organic chemistry, compounds like this are fascinating due to their complexity and the opportunities they provide for innovation. As scientists continue to explore similar derivatives, the potential for new and effective applications grows, reminding us of the boundless possibilities within the world of chemical compounds.
Synonyms
anastrozole
120511-73-1
Arimidex
anastrazole
Anastrozol
ZD1033
2,2'-(5-((1H-1,2,4-triazol-1-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile)
Asiolex
ICI D1033
ZD-1033
ICI-D1033
HSDB 7462
ICI-D 1033
UNII-2Z07MYW1AZ
2Z07MYW1AZ
NSC-719344
NSC-759855
CCRIS 9352
CHEBI:2704
alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
DTXSID9022607
Rvg-106400
NSC719344
CHEMBL1399
DTXCID202607
Anastrozole [USAN:USP:INN:BAN]
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
NSC 719344
NSC 759855
1,3-Benzenediacetonitrile, alpha,alpha,alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-
NCGC00164619-01
2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
ANASTROZOLE (MART.)
ANASTROZOLE [MART.]
ANASTROZOLE (USP-RS)
ANASTROZOLE [USP-RS]
alpha1,alpha1,alpha3,alpha3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
ANASTROZOLE (EP MONOGRAPH)
ANASTROZOLE (USP IMPURITY)
ANASTROZOLE [EP MONOGRAPH]
ANASTROZOLE [USP IMPURITY]
ANASTROZOLE (USP MONOGRAPH)
ANASTROZOLE [USP MONOGRAPH]
Anastrozole (USAN:USP:INN:BAN)
ZD 1033
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
Arimidex (TN)
SMR000466301
CAS-120511-73-1
SR-01000759390
anastrozolum
Anastrozole?
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropanenitrile)
Anastrozole Tablets
2-(3-(1-Cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl)-2-methylpropanenitrile
Anastrozole; 2,2'-[5-(1H-1,2,4-Triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
Anastrozole (Standard)
Arimidex (AstraZeneca)
ANASTROZOLE [MI]
ANASTROZOLE [INN]
ANASTROZOLE [JAN]
ANASTROZOLE [HSDB]
ANASTROZOLE [USAN]
SCHEMBL9726
ANASTROZOLE [WHO-DD]
MLS000759396
MLS001424217
MLS006011961
GTPL5137
Anastrozole (JP18/USP/INN)
Anastrozole - Bio-X trade mark
BDBM10015
ANASTROZOLE [ORANGE BOOK]
L02BG03
BCPP000401
GLXC-03925
HMS2052M11
HMS2089N10
HMS2235M06
HMS3369K05
HMS3394M11
HMS3654I18
HMS3715B05
HMS3742O21
HMS3866K03
ICI-D-1033
Pharmakon1600-01502278
ALBB-037397
BCP02090
VEA51232
Tox21_112238
Tox21_303568
HY-14274R
MFCD00866298
NSC759855
s1188
STL451008
AKOS015894980
tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile
Tox21_112238_1
AC-4234
BCP9000301
CCG-101109
CS-0716
DB01217
FT10600
KS-5052
NC00359
SB17304
3-Phenylene]bis(2-methyl-propiononitrile
NCGC00164619-02
NCGC00164619-04
NCGC00257356-01
BT164176
HY-14274
A2370
NS00005588
SW197739-4
C08159
D00960
EN300-118709
AB00639929-06
AB00639929-08
AB00639929-09
AB00639929-10
AB00639929_11
AB00639929_13
A804526
Q419143
2;2"-[5-(1H-1;2;4-Triazol-1-ylmethyl)-1
SR-01000759390-4
SR-01000759390-5
BRD-K52172416-001-10-6
BRD-K52172416-001-11-4
Z1515385077
1,.alpha.,alpha.,alpha.',.alpha.'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-
2,2'-(5-(1H-1,2,4-Triazol-1-ylmethyl)-1,3-phenylene)di(2-methylpropionitrile)
2,2'-[5-(1H-1,2,4-triazol-1-yl-methyl)-1,3-phenylene]-di(2-methyl propionitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]di(2-methylpropiononitrile)
2,2'-[5-(1H-1,2,4-triazole-1-yl-methyl)-1,3-phenylene]di(2-methyl propionitrile)
2-[3-(2-cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methyl-propanenitrile
a,a,a',a'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
.alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
.ALPHA.,.ALPHA.,.ALPHA.',.ALPHA.'-TETRAMETHYL-5-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-M-BENZENEDIACETONITRILE
1,3-BENZENEDIACETONITRILE,.ALPHA.,.ALPHA.,.ALPHA.',.ALPHA.'-TETRAMETHYL-5-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-
1,3-BENZENEDIACETONITRILE,alpha,alpha,alpha',alpha'-TETRAMETHYL-5-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-
2-[3-(1-cyano-1-methylethyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]phenyl]-2-methylpropanenitrile
alpha, alpha, alpha', alpha'-tetramethylyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
Alpha,alpha,alpha', alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
Solubility of 2-[3-(1-cyano-1-methyl-ethyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methyl-propanenitrile
The compound 2-[3-(1-cyano-1-methyl-ethyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methyl-propanenitrile (C21H22N4) presents a unique solubility profile due to its complex structure and the presence of multiple functional groups. Examining the solubility characteristics provides insights into its behavior in various solvents.
In general, the solubility of such organic compounds can be influenced by:
Due to these factors, this compound is likely to exhibit variable solubility characteristics, being more soluble in organic solvents such as dimethyl sulfoxide (DMSO), dimethylformamide (DMF), or ethanol, rather than in water. This distinction highlights the importance of solvent selection when considering the compound's applications in research or industry.
In conclusion, understanding the solubility of 2-[3-(1-cyano-1-methyl-ethyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methyl-propanenitrile is essential for its practical applications, making solubility a critical parameter to consider in its utilization and study.