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Dicamba

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Identification
Molecular formula
C8H6Cl2N1O3
CAS number
1918-00-9
IUPAC name
2-(2,6-dichloro-3-methyl-anilino)benzoic acid
State
State

Dicamba is in a solid state at room temperature.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
221.05g/mol
Molar mass
221.0470g/mol
Density
1.5700g/cm3
Appearence

Dicamba is a white, crystalline solid. It may have a slight odor and is typically available in powder form. Due to its crystalline structure, it may appear shiny or granular.

Comment on solubility

Solubility of 2-(2,6-dichloro-3-methyl-anilino)benzoic acid

When it comes to the solubility of 2-(2,6-dichloro-3-methyl-anilino)benzoic acid (C8H6Cl2N1O3), several factors play a crucial role:

  • Polarity: The presence of functional groups, specifically the carboxylic acid group (-COOH), contributes to its capacity to interact with polar solvents such as water.
  • Hydrophobic interactions: The aromatic rings and chlorine substitutions add non-polar characteristics, which may limit solubility in polar environments.
  • pH dependency: The solubility of carboxylic acids often increases in higher pH conditions, where deprotonation occurs, forming a negatively charged carboxylate ion.

In summary, while 2-(2,6-dichloro-3-methyl-anilino)benzoic acid exhibits some degree of solubility in polar solvents, its solubility is significantly influenced by the surrounding environment. As a result, solubility may be variable depending on the solvent polarity and pH. For a clearer understanding, empirical data can be invaluable in determining the exact solubility parameters.

Interesting facts

Interesting Facts about 2-(2,6-dichloro-3-methyl-anilino)benzoic Acid

2-(2,6-dichloro-3-methyl-anilino)benzoic acid, often referred to by its systematic name, is a fascinating compound that belongs to the category of anilines. Its unique structure and properties make it a subject of interest in various fields of research.

Chemical Class

  • Anilines: This compound is a derivative of aniline, which is an aromatic amine and is widely used in the synthesis of dyes and pharmaceuticals.
  • Aromatic Acids: The benzoic acid moiety contributes to its acidic properties, making it useful in various chemical reactions.

Applications

The versatility of 2-(2,6-dichloro-3-methyl-anilino)benzoic acid can be seen in several applications:

  • Pharmaceutical Industry: It has been researched for its potential use in drug development, particularly for antihistamines and anti-inflammatory agents.
  • Research Tool: The compound serves as a reference material in analytical chemistry for the development of various testing methods.

Unique Properties

What sets this compound apart from others includes:

  • Halogen Substitution: The presence of chlorine atoms not only influences its reactivity but also enhances its biological activities.
  • Methyl Group Influence: The methyl group attached to the aniline structure can affect solubility and interaction with biological targets.

Safety Considerations

When studying or working with this compound, safety is paramount. Ensure the following precautions are taken:

  • PPE: Always wear appropriate personal protective equipment, including gloves and eye protection.
  • Ventilation: Work within a fume hood to avoid inhalation of any potential harmful vapors.

"The study of compounds like 2-(2,6-dichloro-3-methyl-anilino)benzoic acid not only enhances our chemical knowledge but also contributes to advancements in medicine and materials science."

This compound illustrates the intricate relationships in chemistry between structure and function, providing an excellent opportunity for exploration and discovery.

Synonyms
meclofenamic acid
meclofenamate
644-62-2
Meclophenamic acid
Arquel
Meclomen (free acid)
2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid
Acido meclofenamico
Acide meclofenamique
INF 4668
Meclomen
Acidum meclofenamicum
CI-583
N-(2,6-Dichloro-m-tolyl)anthranilic acid
2-(2,6-dichloro-3-methylanilino)benzoic acid
Acide meclofenamique [INN-French]
Acido meclofenamico [INN-Spanish]
Acidum meclofenamicum [INN-Latin]
INF-4668
N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid
N-(2,6-Dichloro-3-methylphenyl)anthranilic acid
CCRIS 5532
UNII-48I5LU4ZWD
2-((2,6-Dichloro-3-methylphenyl)amino)benzoic acid
EINECS 211-419-5
48I5LU4ZWD
CL-583
NSC 95309
NSC-95309
Benzoic acid, 2-((2,6-dichloro-3-methylphenyl)amino)-
BRN 2221428
CHEBI:6710
benzoic acid, 2-[(2,6-dichloro-3-methylphenyl)amino]-
Anthranilic acid, N-(2,6-dichloro-m-tolyl)-
CHEMBL509
644-62-2 (free acid)
DTXSID0048559
MECLODIUM
2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid
MECLOFENAMIC ACID (MART.)
MECLOFENAMIC ACID [MART.]
Acide meclofenamique (INN-French)
Acido meclofenamico (INN-Spanish)
Acidum meclofenamicum (INN-Latin)
Meclofenamic acid [USAN:INN:BAN]
Arquel Granules
Arquel Tablets
Meclofenamic acid (USAN/INN)
meclofenamic-acid
JMS
CL 583
Spectrum_000893
Prestwick0_000206
Prestwick1_000206
Prestwick2_000206
Prestwick3_000206
Spectrum2_001045
Spectrum3_000486
Spectrum4_000038
Spectrum5_000942
SCHEMBL106
Lopac0_000727
BSPBio_000191
BSPBio_001951
KBioGR_000475
KBioSS_001373
MECLOFENAMATE [VANDF]
2-(2,6-Dichloro-3-methylphenyl)aminobenzoic acid
DivK1c_000504
SPBio_000970
SPBio_002112
MECLOFENAMIC ACID [MI]
BPBio1_000211
GTPL7219
MECLOFENAMIC ACID [INN]
DTXCID3028188
MECLOFENAMIC ACID [USAN]
BDBM22971
KBio1_000504
KBio2_001373
KBio2_003941
KBio2_006509
KBio3_001451
M01AG04
M02AA18
MECLOFENAMIC ACID [VANDF]
NINDS_000504
MECLOFENAMIC ACID [WHO-DD]
NSC95309
AKOS012836983
MECLOFENAMIC ACID [GREEN BOOK]
Anthranilic acid,6-dichloro-m-tolyl)-
DB00939
FM25028
SDCCGSBI-0050705.P005
IDI1_000504
NCGC00021132-01
SBI-0050705.P004
HY-117275
CS-0064844
NS00000697
UNM000001246303
Benzoic acid,6-dichloro-3-methylphenyl)amino]-
C07117
D02341
EN300-708777
G12198
2-((2,6-Dichloro-3-methylphenyl)amino)benzoicacid
Q2823284
2-[(2,6-dichloro-3-methylphenyl)amino]-benzoic acid
BRD-K50398167-236-02-9
BRD-K50398167-236-22-7
BRD-K50398167-323-03-3
2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid;N-(2,6-Dichloro-m-tolyl)anthranilic acid
211-419-5
InChI=1/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19