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Tenatoprazole

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Identification
Molecular formula
C16H13N3O2S
CAS number
117977-21-6
IUPAC name
2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo[4,5-b]pyridine
State
State

Tenatoprazole is a stable solid at room temperature.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
824.15
Boiling point (Kelvin)
1 097.30
General information
Molecular weight
357.41g/mol
Molar mass
357.4140g/mol
Density
1.3958g/cm3
Appearence

Tenatoprazole is typically found as a crystalline solid. It is often off-white to pale yellow in appearance.

Comment on solubility

Solubility of 2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo[4,5-b]pyridine

The solubility of the compound 2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo[4,5-b]pyridine (C16H13N3O2S) can provide significant insights into its potential applications and behavior in various environments. Here are some key points regarding its solubility:

  • Solvent Dependence: The solubility of this compound is highly dependent on the choice of solvent. It is generally expected to be more soluble in polar solvents, such as ethanol and methanol, due to its ability to form hydrogen bonds.
  • Non-Polar Solvents: In contrast, solubility in non-polar solvents like hexane may be considerably lower, highlighting the importance of solvent polarity in influencing solubility.
  • pH Sensitivity: The solubility may also be affected by the pH of the solution, where changes could lead to protonation or deprotonation of functional groups, thus impacting overall solubility.
  • Temperature Effects: As with many other compounds, increasing the temperature typically enhances solubility, allowing for a higher concentration of the compound in solution.

In summary, the solubility of 2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo[4,5-b]pyridine can be characterized as nuanced and is influenced by a variety of factors such as solvent type, temperature, and pH. Understanding these aspects is crucial for its application across different fields.

Interesting facts

Interesting Facts About 2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo[4,5-b]pyridine

This intriguing compound belongs to the class of imidazopyridines, which are noted for their varied biological activities. 2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo[4,5-b]pyridine presents unique features that make it a significant subject of study:

  • Pharmacological Potential: Compounds like this imidazopyridine derivative have been researched for their potential anti-cancer, anti-inflammatory, and antimicrobial properties. Various studies indicate they can interact with biological pathways in unique ways.
  • Sulfoxide Group: The presence of the sulfinyl group (–S(O)–) contributes to the compound's reactivity and solubility in different solvents, which can influence its biological activity.
  • Imidazole Ring: The imidazole moiety is crucial for many pharmacologically active agents, often participating in hydrogen bonding and enzyme binding, thus enhancing the compound's therapeutic effects.
  • Literature Support: Research articles frequently cite this compound when discussing drug development focused on targeting specific enzymes or receptors involved in disease processes.

To quote one study, “The intricate structure of imidazopyridines allows for a diverse range of biological interactions, making them compelling candidates for drug candidates in modern medicinal chemistry.” Such insights underline the importance of understanding compounds like 2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo[4,5-b]pyridine.

Overall, beyond its chemical structure, this compound symbolizes the art and science of drug design, offering a glimpse into the vast possibilities that lie within organic chemistry.

Synonyms
sulmazole
73384-60-8
sulmazol
Vardax
Sulmazole [INN]
Sulmazolum
Sulmazol [INN-Spanish]
Sulmazolum [INN-Latin]
AR-L 115BS
2-[2-methoxy-4-(methylsulfinyl)phenyl]-1H-imidazo[4,5-b]pyridine
AR-L 115-BS
CHEBI:34988
EINECS 277-406-1
UNII-HK56EH9K44
NSC-757867
BRN 0818370
AR-L-115BS
HK56EH9K44
DTXSID1040617
AR-L-115
SULMAZOLE [MI]
SULMAZOLE [MART.]
CHEMBL286020
DTXCID9020617
1H-Imidazo(4,5-b)pyridine, 2-(2-methoxy-4-(methylsulfinyl)phenyl)-
2-(2-Methoxy-4-(methylsulfinyl)phenyl)-1H-imidazo(4,5-b)pyridine
2-(2-Methoxy-4-(methylsulfinyl)phenyl)-3H-imidazo(4,5-b)pyridine
2-(2-Methoxy-4-(methylsulfinyl)phenyl)-3H-imidazo[4,5-b]pyridine
3H-Imidazo[4,5-b]pyridine,2-[2-methoxy-4-(methylsulfinyl)phenyl]-
NSC 757867
NCGC00016924-02
Sulmazol (INN-Spanish)
Sulmazolum (INN-Latin)
2-((2-methoxy-4-methylsulfinyl)phenyl)-H-imidazo(4,5-b)pyridine
2-(2-Methoxy-4-[methylsulfinyl]phenyl)-1H-imidazo(4,5-b)pyridine
2-[2-methoxy-4-(methylsulfinyl)phenyl]-3H-imidazo[4,5-b]pyridine
CAS-73384-60-8
SULMAZOLE (MART.)
AR-L 115 BS
3H-IMIDAZO(4,5-B)PYRIDINE, 2-(2-METHOXY-4-(METHYLSULFINYL)PHENYL)-
BWA746C
BW A746C
AR-L115
SR-01000841215
MG 28734
MG-28734
2-(2-methoxy-4-(methylsulfinyl)phenyl)-1H-imidazo[4,5-b]pyridine
Prestwick_1012
Spectrum_001155
2-(2-methoxy-4-methylsulfinylphenyl)-1H-imidazo[4,5-b]pyridine
Prestwick0_000641
Prestwick1_000641
Prestwick2_000641
Prestwick3_000641
Spectrum3_000733
Spectrum4_001246
Spectrum5_002074
BSPBio_000641
BSPBio_002286
KBioGR_001772
KBioSS_001635
MLS002153927
DivK1c_000276
SCHEMBL187165
SPECTRUM1501159
SPBio_002562
BPBio1_000707
AR-L-115-BS
HMS500N18
KBio1_000276
KBio2_001635
KBio2_004203
KBio2_006771
KBio3_001506
NINDS_000276
HMS1570A03
HMS2097A03
HMS2230O09
HMS3371L17
HMS3714A03
Pharmakon1600-01501159
Tox21_110685
BDBM50000056
BDBM50225309
CCG-38446
NSC757867
AKOS040749578
CCG-220641
IDI1_000276
NCGC00016924-01
NCGC00095999-01
DA-03205
SMR001233271
TS-08638
SBI-0051668.P002
HY-116675
AB00052230
CS-0066237
NS00037510
SR-01000841215-2
SR-01000841215-3
BRD-A22081593-001-04-6
BRD-A22081593-001-06-1
BRD-A22081593-001-11-1
Q27116354
2-methoxy-4-(methylsulfinyl)-phenylimidazo[4,5-b]pyridine
2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo[4,5-b]pyridine
2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[4,5-b]pyridine
2-(4-Methanesulfinyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine
2-Methyl-6-oxo-1,6-dihydro-[3,4'']bipyridinyl-5-carbonitrile
(sulmazole)2-(4-Methanesulfinyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine
2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[4,5-b]pyridine (sulmazole)
2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[4,5-b]pyridine(sulmazole)
277-406-1