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2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine

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Identification
Molecular formula
C15H13N3O
CAS number
171599-83-0
IUPAC name
2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine
State
State

At room temperature, the compound is in a solid state. It exists as a crystalline powder, which is characteristic of many similar organic compounds. The solid nature is stable under ambient conditions, maintaining its form outside of aqueous and highly acidic or basic environments.

Melting point (Celsius)
286.00
Melting point (Kelvin)
559.15
Boiling point (Celsius)
114.00
Boiling point (Kelvin)
387.15
General information
Molecular weight
251.29g/mol
Molar mass
251.2850g/mol
Density
1.3200g/cm3
Appearence

The compound is typically a crystalline solid with a distinct structure. The compound appears as off-white to pale yellow crystalline powder. Under visible light, it shows typical characteristics of small, crystalline particles that are uniform in appearance. The texture and form are consistent under normal laboratory conditions.

Comment on solubility

Solubility of 2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine

The compound 2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine, with the chemical formula C15H13N3O, showcases interesting solubility characteristics that are worth exploring.

General Insights

Understanding the solubility of this compound involves several key factors:

  • Polarity: The presence of a hydroxyl group (-OH) suggests potential for hydrogen bonding, which can enhance solubility in polar solvents.
  • Size and Structure: The bulky indole and carboxamidine groups may hinder solubility in certain solvents, leading to varied solubility profiles.
  • Solvent Dependence: Like many organic compounds, solubility can differ markedly between polar and nonpolar solvents.

Solubility Profiles

In practice, the solubility of 2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine can be summarized as follows:

  • Water: Limited solubility may be observed due to its organic nature, despite the -OH group.
  • Organic Solvents: Likely to demonstrate better solubility in solvents like ethanol or DMSO, thanks to their capacity to interact with the functional groups present.

As noted, solubility is a complex attribute influenced by the chemical structure and the environment in which the compound exists. Therefore, researchers should consider these factors in experimental applications.

Interesting facts

Interesting Facts about 2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine

2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine is a fascinating compound that has garnered attention in various fields, particularly in medicinal chemistry. Here are some engaging facts about this compound:

  • Structure and Versatility: The compound features a complex structure that includes an indole ring fused with a hydroxyl group and a carboxamidine moiety. This structure contributes to its unique properties and potential applications.
  • Biological Significance: Compounds similar to 2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine have been studied for their biological activities. They may exhibit various pharmacological effects, potentially serving as leads in drug development.
  • Research Potential: According to recent studies, derivatives of this compound have shown promise in targeting specific disease pathways, including those related to cancer and neurodegenerative disorders. The ongoing research aims to unveil more about its therapeutic benefits.
  • Synthesis and Chemistry: The synthesis of 2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine often involves intricate organic reactions, showcasing the creativity and skill required in synthetic chemistry. Understanding these reactions is crucial for chemists aiming to create new analogs with enhanced activity.

As a chemistry student or scientist, exploring compounds like 2-(2-hydroxyphenyl)-1H-indole-5-carboxamidine not only enhances your understanding of chemical structures but also emphasizes the significance of structure-activity relationships in drug discovery. The world of chemical compounds is rich with diversity, and each has its own story waiting to be told!

Synonyms
2-(2-hydroxyphenyl)-1H-indole-5-carboximidamide
CRA-8328
179748-10-8
CHEMBL284805
1gi6
SCHEMBL4995709
BDBM14327
DTXSID10274311
BDBM50102768
PD042549
NS00069136
2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}benzen-1-olate