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Thiodiglycol

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Identification
Molecular formula
C4H10O2S
CAS number
111-48-8
IUPAC name
2-(2-hydroxyethylsulfanyl)ethanol
State
State

At room temperature, Thiodiglycol is a liquid.

Melting point (Celsius)
-2.85
Melting point (Kelvin)
270.30
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.00
General information
Molecular weight
122.18g/mol
Molar mass
122.1800g/mol
Density
1.2610g/cm3
Appearence

Thiodiglycol is a colorless, viscous liquid. It is often described as having a slight sulfur-like smell. The compound is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 2-(2-hydroxyethylsulfanyl)ethanol (C4H10O2S)

The solubility characteristics of 2-(2-hydroxyethylsulfanyl)ethanol, a compound featuring both alcohol and thiol functional groups, can be quite intriguing. Here are some key points to consider:

  • Polar Nature: Due to the presence of hydroxyl (-OH) and sulfhydryl (-SH) groups, this compound displays a significant degree of polarity. This typically enhances its solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of the -OH group to form hydrogen bonds can further increase solubility, allowing it to interact favorably with water molecules.
  • Solvent Compatibility: Generally, compounds such as this one are soluble in alcohols and ether, while their solubility in non-polar solvents, such as hydrocarbons, is considerably less.
  • Concentration Dependence: The solubility may depend on the concentration of the compound and the temperature of the solution, often increasing with higher temperatures.

In conclusion, 2-(2-hydroxyethylsulfanyl)ethanol exhibits relatively good solubility characteristics in polar solvents, driven by its functional groups. As with many compounds, the specific conditions such as pH and temperature can also affect its solubility profile.

Interesting facts

Interesting Facts About 2-(2-Hydroxyethylsulfanyl)ethanol

2-(2-Hydroxyethylsulfanyl)ethanol, often referred to in scientific literature as a thioalcohol, is a fascinating compound due to its diverse applications and properties. Here are some key highlights:

  • Antioxidant Properties: This compound is noted for exhibiting antioxidant properties, making it beneficial in various biological environments. The presence of the sulfanyl group plays a crucial role in scavenging free radicals.
  • Biocompatibility: Its structure suggests a high degree of biocompatibility, which is essential for applications in pharmaceuticals and biochemistry.
  • Applications: It serves as a versatile building block in synthesizing other chemical compounds. Researchers find its use in the development of various medicinal drugs.
  • Solvent and Reagent: The compound is often employed as a solvent and a reagent in laboratory environments, facilitating numerous chemical reactions.
  • Research Implications: Due to ongoing research on its potential therapeutic effects, 2-(2-hydroxyethylsulfanyl)ethanol represents a significant area of interest for chemists looking to explore new drug formulations.

In conclusion, 2-(2-hydroxyethylsulfanyl)ethanol is not just a simple thioalcohol; its unique chemical properties and wide array of applications make it a compound worth studying further. As the exploration of its capabilities continues, this compound could reveal new avenues for medical and industrial applications.

Synonyms
thiodiglycol
2,2'-Thiodiethanol
111-48-8
Thiodiethanol
Thiodiethylene glycol
Tedegyl
Kromfax solvent
Bis(2-hydroxyethyl) sulfide
Ethanol, 2,2'-thiobis-
Bis(2-hydroxyethyl)sulfide
2,2-Thiodiethanol
Glyecine A
2,2'-Thiodiglycol
2,2'-THIOBISETHANOL
Tiodiglicol
Di(2-hydroxyethyl) sulfide
2-(2-hydroxyethylsulfanyl)ethanol
Bis(2-hydroxyethyl) thioether
Thiodiglycolum
Tiodiglicolo
beta-Hydroxyethyl sulfide
Sulfide, bis(2-hydroxyethyl)
Thiodiglycol [INN]
Dihydroxyethyl sulfide
Ethanol, 2,2'-thiodi-
Diethanol sulfide
bis(hydroxyethyl)sulfide
Bis(beta-hydroxyethyl) sulfide
beta,beta'-Dihydroxyethyl sulfide
Tiodiglicolo [DCIT]
beta,beta'-Dihydroxydiethyl sulfide
Bis(beta-hydroxyethyl)sulfide
beta-Thiodiglycol
2,2'-Thiobis(ethanol)
3-Thiapentane-1,5-diol
.beta.-Thiodiglycol
Tiodiglicol [INN-Spanish]
2-[(2-hydroxyethyl)sulfanyl]ethan-1-ol
Thiodiglycolum [INN-Latin]
NSC 6289
Bis(2-hydroxyethyl) sulphide
HSDB 7482
2,2'-Thiobis[ethanol]
2,2'-sulfanediyldiethanol
Kromfax@ Solvent
NSC-6289
.beta.-Hydroxyethyl sulfide
Bis(b-hydroxyethyl) sulfide
EINECS 203-874-3
UNII-9BW5T43J04
beta-Bis(hydroxyethyl) sulfide
BRN 1236325
DTXSID6026878
CHEBI:75184
AI3-05541
.beta.-Bis(hydroxyethyl) sulfide
Bis(.beta.-hydroxyethyl) sulfide
beta-hydroxyethyl sulfid
MFCD00002910
.beta.,.beta.'-Dihydroxyethyl sulfide
THIODIGLYCOL [HSDB]
.beta.,.beta.'-Dihydroxydiethyl sulfide
DTXCID506878
NSC6289
EC 203-874-3
9BW5T43J04
2,2'-THIODIETHANOL [MI]
NCGC00095074-01
Tiodiglicol (INN-Spanish)
Thiodiglycolum (INN-Latin)
2,2'-sulfobisethanol
2-((2-hydroxyethyl)sulfanyl)ethan-1-ol
CAS-111-48-8
Diethanolsulfide
2-[(2-hydroxyethyl)thio]ethanol
2,2'Thiodiglycol
2,2'thiodiethanol
2,2'Thiobisethanol
2,2`-Thiodiethanol
Ethanol,2'-thiodi-
Ethanol,2'-thiobis-
Tiodiglicol (Spanish)
2-Hydroxyethyl Sulfide
betaHydroxyethyl sulfide
Ethanol, 2,2'thiodi
Spectrum_001701
Thiodiglycolum (Latin)
2,2'-Thiodi-Ethanol
Ethanol, 2,2'thiobis
2,2'-Thiobis-Ethanol
Bis(2hydroxyethyl)sulfide
Spectrum2_000407
Spectrum4_000213
Di(2hydroxyethyl) sulfide
Bis(2hydroxyethyl) sulfide
Bis(betahydroxyethyl)sulfide
THIODIGLYCOL [INCI]
Sulfide, bis(2hydroxyethyl)
WLN: Q2S2Q
Bis(2hydroxyethyl) thioether
SCHEMBL40132
Bis(betahydroxyethyl) sulfide
KBioGR_000845
KBioSS_002181
1,5-dihydroxy-3-thiapentane
2,2'-thiobis(ethan-1-ol)
SPECTRUM1503325
2-(2-hydroxyethylthio)ethanol
bis-(2-hydroxyethyl) sulphide
SPBio_000334
CHEMBL444480
SCHEMBL6679983
beta,beta'Dihydroxyethyl sulfide
KBio2_002181
KBio2_004749
KBio2_007317
2,2'-Thiodiethanol, >=99%
beta,beta'Dihydroxydiethyl sulfide
HMS1922I18
Pharmakon1600-01503325
HY-B0913
MSK159274_C
Tox21_111413
Tox21_200827
CCG-39716
NSC758456
STL302034
AKOS009031578
Tox21_111413_1
Bis(2-hydroxyethyl)sulfide;Thiodiglycol
FT30602
NSC-758456
NCGC00095074-02
NCGC00095074-03
NCGC00095074-05
NCGC00258381-01
2,2'-Thiodiethanol, >=99.0% (GC)
SBI-0051909.P002
DB-060096
NS00009553
T0202
2,2'-Thiodiethanol, purum, >=95.0% (GC)
2,2'-Thiodiethanol 1000 microg/mL in Methanol
AB00052435_02
2,2'-Thiodiethanol, puriss., >=98.5% (GC)
A802371
Q418117
SR-01000872773
SR-01000872773-1
BRD-K54521836-001-02-1
2,2'-Thiodiethanol, >=99.0%, suitable for amino acid analysis
2,2'-Thiodiethanol; 2,2?-Thiobis(ethanol), Bis(2-hydroxyethyl) sulfide, Thiodiethylene glycol, Thiodiglycol
203-874-3