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Dibazetidine

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Identification
Molecular formula
C20H15N3O
CAS number
76941-12-5
IUPAC name
2-(2-hydroxy-3-phenyl-phenyl)-3H-benzimidazole-5-carboxamidine
State
State
Dibazetidine is typically found as a solid at room temperature, usually in the form of crystalline powders or granules.
Melting point (Celsius)
245.00
Melting point (Kelvin)
518.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
327.36g/mol
Molar mass
327.3790g/mol
Density
1.3294g/cm3
Appearence

Dibazetidine typically appears as a crystalline solid. The crystals can be off-white to pale yellow in color, depending on the specific sample and purity.

Comment on solubility

Solubility of 2-(2-hydroxy-3-phenyl-phenyl)-3H-benzimidazole-5-carboxamidine

The solubility of 2-(2-hydroxy-3-phenyl-phenyl)-3H-benzimidazole-5-carboxamidine (C20H15N3O) can present interesting characteristics due to its complex structure. The solubility of this compound is influenced by several factors:

  • Polarity: The presence of the hydroxy (-OH) group can enhance the solubility in polar solvents by forming hydrogen bonds.
  • Hydrophobic interactions: The phenyl groups contribute to hydrophobic characteristics, making it less soluble in highly polar solvents.
  • pH dependence: As a carboxamidine, the solubility may vary with changes in pH, as protonation states could alter solubility patterns.

In general, compounds like this one often show better solubility in organic solvents such as dimethyl sulfoxide (DMSO) or methanol compared to water.
It is essential to conduct experimental solubility tests under various conditions to accurately determine how this compound behaves in practical applications.

Interesting facts

Interesting Facts about 2-(2-hydroxy-3-phenyl-phenyl)-3H-benzimidazole-5-carboxamidine

This unique compound, known for its complex structure, combines elements from both benzimidazole and carboxamidine, making it a fascinating subject for chemists and drug developers alike. Here are some engaging tidbits about this intriguing molecule:

  • Versatility in Biological Applications: Compounds like this one have been explored for their potential in medicinal chemistry, particularly in the development of pharmaceutical agents that target various biological pathways.
  • Structural Significance: The inclusion of a hydroxyl (-OH) group and phenyl rings contributes to the compound's functionality, possibly enhancing its interactions with biological targets.
  • Research Focus: Scientists are increasingly interested in benzimidazole derivatives due to their broad range of biological activities, including anti-cancer, anti-inflammatory, and antimicrobial properties.
  • Chemical Diversity: The fusion of multiple functional groups within this compound showcases the diversity possible in organic synthesis, opening avenues for further modifications and optimizations.
  • Historical Context: Benzimidazoles have been pivotal in the development of several important therapeutic agents, demonstrating how structural modifications can lead to novel properties and applications.

As a testament to its structural complexity and potential applications, 2-(2-hydroxy-3-phenyl-phenyl)-3H-benzimidazole-5-carboxamidine exemplifies the intersection of organic chemistry and pharmacology. Its continued study can yield insights that not only advance scientific understanding but also foster innovative solutions in drug discovery.

Synonyms
2-(2-hydroxy-biphenyl)-1h-benzoimidazole-5-carboxamidine
CHEMBL327715
2-(2-hydroxy-3-phenylphenyl)-1H-1,3-benzodiazole-5-carboximidamide
3-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}-1,1'-BIPHENYL-2-OLATE
2-{2-hydroxy-[1,1'-biphenyl]-3-yl}-1H-1,3-benzodiazole-5-carboximidamide
1gjb
1gjc
2-(2-hydroxy-(1,1'-biphenyl)-3-yl)-1H-1,3-benzodiazole-5-carboximidamide
3-(5-(AMINO(IMINIO)METHYL)-1H-BENZIMIDAZOL-2-YL)-1,1'-BIPHENYL-2-OLATE
1gj5
1o3b
1o3c
1o3d
SCHEMBL1302567
BDBM14143
BDBM14325
1o39
APC-7806
CRA-7806
CRA_7806
DB01725
PD005858
NS00068939
Q27095760
2-(2-hydroxybiphenyl-3-yl)-1H-benzimidazole-5-carboximidamide
3-{5-[amino(iminio)methyl]-1H-benzimidazol-2-yl}biphenyl-2-olate
2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-6-phenylbenzen-1-olate