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Phosphatidylcholine

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Identification
Molecular formula
C26H52NO8P
CAS number
8002-43-5
IUPAC name
2-[(2-docosa-4,7,10,13,16,19-hexaenoyloxy-3-hexadecoxy-propoxy)-hydroxy-phosphoryl]oxyethyl-trimethyl-ammonium
State
State

At room temperature, phosphatidylcholines are generally found as solids, although they are typically handled in solution forming part of liposomal membranes, depending on their fatty acid chain length and degree of saturation.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.00
Boiling point (Celsius)
600.00
Boiling point (Kelvin)
873.00
General information
Molecular weight
758.13g/mol
Molar mass
758.1330g/mol
Density
1.0360g/cm3
Appearence

Phosphatidylcholines are typically found as a yellow-brown powder or as a part of liposomal or micellar formations in solution. As a major component of biological membranes, they do not have a singular appearance but rather contribute to the structural integrity of cellular barriers.

Comment on solubility

Solubility of 2-[(2-docosa-4,7,10,13,16,19-hexaenoyloxy-3-hexadecoxy-propoxy)-hydroxy-phosphoryl]oxyethyl-trimethyl-ammonium (C26H52NO8P)

The solubility of the compound 2-[(2-docosa-4,7,10,13,16,19-hexaenoyloxy-3-hexadecoxy-propoxy)-hydroxy-phosphoryl]oxyethyl-trimethyl-ammonium is quite intriguing and can be influenced by several factors. Understanding its solubility is crucial for applications in biochemical research and industrial formulations.

Factors Affecting Solubility

  • Polarity: The presence of ionic groups, such as the trimethylammonium and phosphate moieties, significantly enhances the solubility in polar solvents, particularly water.
  • Hydrophobic Chains: The long hydrocarbon chains (docosahexaenoic and hexadecane moieties) may reduce solubility in polar solvents but increase solubility in non-polar environments.
  • Temperature: Increased temperature can lead to higher solubility, especially for compounds that exhibit some degree of hydrophobic character.

Due to its amphiphilic nature, the compound has a dual character: it can dissolve well in both aqueous and organic solvents depending on the environment. In polar solvents, it may enhance its solubility due to charge interactions, while in non-polar solvents, the hydrophobic sections may dominate.

Quotes from Research

As noted in various studies, "The solubility behavior of phospholipid-like compounds is determined by the balance between hydrophilic and hydrophobic interactions," underscoring the complexity of predicting solubility in various media.

In summary, the solubility of C26H52NO8P illustrates a fascinating interplay of structural components, making it versatile for different applications in chemical processes.

Interesting facts

Exploring 2-[(2-docosa-4,7,10,13,16,19-hexaenoyloxy-3-hexadecoxy-propoxy)-hydroxy-phosphoryl]oxyethyl-trimethyl-ammonium

2-[(2-docosa-4,7,10,13,16,19-hexaenoyloxy-3-hexadecoxy-propoxy)-hydroxy-phosphoryl]oxyethyl-trimethyl-ammonium, often referred to for its complex structure, is a fascinating compound that showcases the intricate interplay between chemical functionalities and biological applications. Here are some intriguing facts about this compound:

  • Biological Relevance: This compound is part of a class of phospholipids, which are vital components of cell membranes. Their unique structure allows them to facilitate the formation of lipid bilayers, essential for cell integrity and function.
  • Membrane Interaction: The presence of both hydrophilic (water-attracting) and hydrophobic (water-repelling) segments in the molecule enables it to interact effectively with biological membranes, thereby influencing membrane fluidity and permeability.
  • Targeted Drug Delivery: Due to its amphiphilic nature, this compound can be employed in targeted drug delivery systems. It can encapsulate therapeutic agents and improve their transport across cell membranes.
  • Synthetic Pathways: The synthesis of this compound involves multiple steps, incorporating various reaction techniques, which highlights the innovation and creativity required in synthetic organic chemistry.
  • Research Applications: Scientists are investigating the potential of this compound in nanotechnology and biomedicine, with the hope of developing new ways to deliver drugs or genetic material to specific cells.

As emphasized by leading researchers in the field, "The understanding and manipulation of phospholipids have revolutionary potential in modern medicine." Such compounds are at the forefront of biochemistry and materials science, showcasing how chemistry not only elucidates fundamental processes but also paves the way for future technological advancements.

In summary, 2-[(2-docosa-4,7,10,13,16,19-hexaenoyloxy-3-hexadecoxy-propoxy)-hydroxy-phosphoryl]oxyethyl-trimethyl-ammonium is more than just a complex chemical entity; it represents a bridge between chemistry and biology, with implications that could reshape therapeutic strategies and enhance our understanding of cellular structures.

Synonyms
132213-85-5