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Tiaprofenic acid

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Identification
Molecular formula
C14H16O3S
CAS number
20165-70-0
IUPAC name
2-[2-cyclopentyl-2-hydroxy-2-(2-thienyl)acetyl]oxyethyl-diethyl-methyl-ammonium
State
State

Tiaprofenic acid is a solid at room temperature. It is typically supplied in its crystalline form for pharmaceutical applications.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
263.34g/mol
Molar mass
263.3360g/mol
Density
1.2700g/cm3
Appearence

Tiaprofenic acid is a white or off-white crystalline powder. It is odorless with a slightly bitter taste.

Comment on solubility

Solubility of 2-[2-cyclopentyl-2-hydroxy-2-(2-thienyl)acetyl]oxyethyl-diethyl-methyl-ammonium

The solubility characteristics of the compound 2-[2-cyclopentyl-2-hydroxy-2-(2-thienyl)acetyl]oxyethyl-diethyl-methyl-ammonium (C14H16O3S) are influenced by its unique structural features. Understanding its solubility can be crucial for various applications in chemical and pharmaceutical contexts.

Key Factors Influencing Solubility:

  • Polarity: The presence of both hydrophilic hydroxyl groups (-OH) and the ammonium group may enhance water solubility, promoting interactions with polar solvents.
  • Hydrophobicity: The cyclopentyl and thienyl groups introduce hydrophobic characteristics, which can limit solubility in water.
  • pH Sensitivity: The ionization of the ammonium group can vary with pH, potentially affecting its solubility in aqueous solutions.

Generally, the compound is expected to be more soluble in organic solvents due to its hydrophobic regions. Studies may indicate that it dissolves well in:

  • Alcohols
  • Aromatic solvents
  • Aqueous solutions when suitably modified

In practice, when evaluating the solubility of such a compound, the observation might be that:

"Its solubility behavior is a fine balance between its polar and non-polar interactions."

Overall, detailed solubility assessments under varying conditions will be essential for practical applications, especially in formulations where precise solubility profiles are necessary.

Interesting facts

Interesting Facts about 2-[2-cyclopentyl-2-hydroxy-2-(2-thienyl)acetyl]oxyethyl-diethyl-methyl-ammonium

This compound, commonly referred to for its unique structural characteristics, belongs to a class of ammonium compounds that exhibit interesting properties and potential applications in various fields. Here are some noteworthy aspects:

  • Structural Diversity: The compound features a distinctive combination of a cyclopentyl ring, a thienyl group, and an ammonium moiety, highlighting the complexity of organic molecules. This structural diversity often correlates with unique biological activities.
  • Pharmacological Potential: Due to the presence of the thienyl functional group, compounds like this one can be explored for their pharmacological properties, potentially exhibiting anti-inflammatory or analgesic effects.
  • Ammonium Characteristics: The diethyl-methyl-ammonium group suggests a quaternary ammonium compound, which can influence solubility and reactivity. Quaternary ammonium salts are often used in various applications, from surfactants to antimicrobial agents.
  • Hydroxyl Impact: The hydroxyl (-OH) group in the structure is essential for hydrogen bonding, enhancing the compound's solubility in polar solvents and impacting its biological interactions.

As a scientist or a chemistry student, delving into the synthesis and characterization of such a compound provides an excellent opportunity to explore organic synthesis techniques and the nuances of structure-activity relationships. This compound not only enriches our understanding of organic chemistry but also opens the door to potential applications across pharmaceuticals and materials science.

Synonyms
Penthienate
Penthienate ion
Penthienate cation
22064-27-3
6LCT38OJV9
Penthienate [BAN]
UNII-6LCT38OJV9
PENTHIENATE [WHO-DD]
2-(2-cyclopentyl-2-hydroxy-2-thiophen-2-ylacetyl)oxyethyl-diethyl-methylazanium
Ethanaminium, 2-((cyclopentylhydroxy-2-thienylacetyl)oxy)-N,N-diethyl-N-methyl-
2-((cyclopentylhydroxy-2-thienylacetyl)oxy)-N,N-diethyl-N-methylethanaminium
AMMONIUM, DIETHYL(2-HYDROXYETHYL)METHYL-, .ALPHA.-CYCLOPENTYL-2-THIOPHENEGLYCOLATE (ESTER)
ETHANAMINIUM, 2-((2-CYCLOPENTYL-2-HYDROXY-2-(2-THIENYL)ACETYL)OXY)-N,N-DIETHYL-N-METHYL-
(2-((2-cyclopentyl-2-hydroxy-2-(thiophen-2-yl)acetyl)oxy)ethyl)diethylmethylazanium
(2-{[2-cyclopentyl-2-hydroxy-2-(thiophen-2-yl)acetyl]oxy}ethyl)diethylmethylazanium
Ammonium, diethyl(2-hydroxyethyl)methyl-, alpha-cyclopentyl-2-thiopheneglycolate (ester)
CHEMBL2110700
DTXSID80871533
CHEBI:135447
DB13695
NS00041376
Q15409352