Skip to main content

Clorazepate

ADVERTISEMENT
Identification
Molecular formula
C16H11ClN2O3
CAS number
62-67-5
IUPAC name
2-(2-chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one
State
State

At room temperature, Clorazepate is in a solid state. It is typically provided in the form of tablets for pharmaceutical use.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
316.75g/mol
Molar mass
316.7460g/mol
Density
1.3200g/cm3
Appearence

Clorazepate is a crystalline solid. It usually appears as white or slightly yellow crystals. This compound may have a faint odor.

Comment on solubility

Solubility of 2-(2-chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one

The solubility of 2-(2-chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one is influenced by several factors, including its chemical structure and the nature of the solvent used. Understanding these aspects can provide valuable insights into its behavior in different environments.

Key points of solubility:

  • Generally, compounds with polar functional groups exhibit higher solubility in polar solvents such as water, while non-polar compounds are more soluble in non-polar solvents.
  • The presence of the chloroethyl group in the structure can enhance solubility in organic solvents due to its polar character.
  • On the other hand, the benzoxazin core may result in lower solubility in aqueous solutions due to its larger hydrophobic structure.

It is essential to note that the solubility can vary significantly based on temperature and pressure. As a general trend:

  • Increased temperature: Often leads to increased solubility for many solid compounds.
  • Pressure: Primarily affects gases, whereas its effect on solids and liquids may be negligible.

In conclusion, while it is challenging to provide a definitive solubility value for 2-(2-chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one without empirical data, the interplay between its functional groups and environmental conditions plays a crucial role in determining its solubility.

Interesting facts

Interesting Facts about 2-(2-Chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one

2-(2-Chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one is a fascinating compound that has garnered attention in various fields of research due to its unique structure and potential applications.

Key Features

  • Antimicrobial Properties: This compound has shown promising results in scientific studies for its ability to inhibit the growth of certain microorganisms, making it a candidate for development in medicinal chemistry.
  • Biological Activity: Its structural composition allows it to interact with biological systems, providing a basis for exploration in drug design and development.
  • Synthetic Utility: The synthesis of this compound often involves strategic transformations, making it an excellent subject for organic chemists interested in synthetic methodologies.

Chemical Significance

The benzoxazinone moiety present in this compound is notable for its involvement in several biological processes. Compounds containing this structure are often studied for their roles in:

  • Plant defense mechanisms
  • Development of agrochemicals
  • Anti-cancer research

Research Potential

Given its novel structure, 2-(2-Chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one is an intriguing target for further research. As one chemist stated, “The exploration of benzoxazinones might unlock new pathways in therapeutic interventions.” This compound could be pivotal in future studies aiming to enhance therapeutic efficacy or develop new materials.

In summary, 2-(2-Chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one represents a blend of organic chemistry and biological applications, warranting further investigation into its properties and potential uses.

Synonyms
Chlorthenoxazine
132-89-8
Reumagrip
Apirazin
Valmorin
Ossazone
Valtorin
Chlorthenoxazin
Chlorethylbenzmethoxazone
Ossipirina
Piroxina
Reulin
AP 67
Clortenoxazina
4H-1,3-BENZOXAZIN-4-ONE, 2-(2-CHLOROETHYL)-2,3-DIHYDRO-
2-(2-Chloroethyl)-3-aza-4-chromanone
2-(2-chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one
NSC 525254
2-(2-Chloroethyl)-2,3-dihydro-4H-1,3-benzoxazin-4-one
NSC-525254
2-(2-Chloroethyl)-2,3-dihydro-4-oxo-1,3-benzoxazine
CHEMBL124815
KA0B657LV3
AP-67
Reugaril
Betix
2-(2-Chloroethyl)-2H-1,3-benzoxazin-4(3H)-one
2-(2-chloroethyl)-3,4-dihydro-2H-1,3-benzoxazin-4-one
Ossapirina
Chlorthenoxazine [INN]
Chlorthenoxazinum
Chlorthenoxazin(e)
Clortenoxazina [INN-Spanish]
Chlorthenoxazinum [INN-Latin]
EINECS 205-082-3
BRN 0170863
Chlorthenoxazine [INN:BAN]
UNII-KA0B657LV3
Benzmethoxazone
4-Oxo-2-(beta-chloroethyl)-2,3-dihydrobenzo-1,3-oxazine
2-(beta-Chloroethyl)-2,3-dihydro-4-oxo(benzo-1,3-oxazine)
SCHEMBL25595
4-27-00-02766 (Beilstein Handbook Reference)
CHLORTHENOXAZIN(E) [MI]
CHLORTHENOXAZINE [MART.]
NIOSH/DM3743000
component of Fiobrol (Salt/Mix)
CHLORTHENOXAZINE [WHO-DD]
DTXSID70861786
CHEBI:134882
component of Trigatan (Salt/Mix)
AAA13289
EX-A4522
WLN: T66 BVM EO DHJ D2G
BDBM50106191
NSC525254
2-(2-Chloroethyl)-2,3-benzoxazine
AKOS034122341
CS-6577
2-(.beta.-chloroethyl)-2,3-oxazine)
DA-72185
TS-07970
2-(2-Chloroethyl)-2,3-benzoxazin-4-one
4H-1, 2-(2-chloroethyl)-2,3-dihydro-
HY-101751
4-Oxo-2-(.beta.-chloroethyl)-2,3-oxazine
DM37430000
NS00001247
EN300-257452
F95288
Q27282145
2-(2-chloroethyl)-2H-benzo[e][1,3]oxazin-4(3H)-one
2-(beta-Chlorathyl)-2,3-dihydro-4-oxobenz-1,3-oxazin
Z1269198910
2-(.beta.-chloroethyl)-2,3-dihydro-4-oxo(benzo-1,3-oxazine)
4-Oxo-2-(.beta.-chloroethyl)-2,3-dihydrobenzo-1,3-oxazine
4H-1,3-Benzoxazin-4-one, 2,3-dihydro-2-(2-chloroethyl)-
2-(2-Chloro-ethyl)-2,3-dihydro-benzo[e][1,3]oxazin-4-one (Chlorthenoxazin)