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Adenosine monophosphate (AMP)

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[2-(2-amino-6-oxo-3H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl] dihydrogen phosphate
State
State

AMP is a solid at room temperature.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
2.4600g/cm3
Appearence

Adenosine monophosphate (AMP) typically appears as a white to off-white crystalline powder. It is odorless and soluble in water, reflecting its role as a biochemical in aqueous solutions.

Comment on solubility

Solubility of [2-(2-amino-6-oxo-3H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl] dihydrogen phosphate

The solubility of the compound with the formula C10H14N5O7P can be quite complex due to its unique structure. Here are some key points to consider:

  • Polar Functional Groups: The presence of dihydrogen phosphate and multiple hydroxyl (-OH) groups indicates that the compound is likely to be polar. Compounds that are polar generally exhibit higher solubility in polar solvents such as water.
  • Hydrophilic Nature: The hydroxymethyl and amino groups can enhance the hydrophilicity of the molecule, promoting its interaction with water molecules, thus potentially increasing solubility in aqueous systems.
  • Potential for Ionization: The dihydrogen phosphate group can easily dissociate, especially in basic conditions, leading to enhanced solubility due to increased ionic character.
  • Solvent Polarity: While this compound may be soluble in water, it could have variable solubility in less polar solvents like ethanol or acetone.

In summary, one could hypothesize that the solubility of this compound in aqueous environments would be significant due to the combination of its polar groups and potential ionization. However, precise solubility would require empirical data to confirm these predictions. The statement that "solubility is a reflection of molecular interaction with the solvent" holds true here, and the multilayered aspects of the molecule contribute to its behavior in different environments.

Interesting facts

Interesting Facts about [2-(2-amino-6-oxo-3H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl] dihydrogen phosphate

This complex compound, often referred to in biochemical contexts, holds significant importance due to its role in biological systems. Here are some fascinating insights into its characteristics and functions:

  • Nucleic Acid Connection: As a derivative of purine, this compound is closely related to nucleic acids—essential building blocks of DNA and RNA.
  • Enzymatic Reactions: It can participate in various enzymatic reactions, aiding in metabolic pathways crucial for energy transfer.
  • Structure Functionality: The presence of a hydroxymethyl group enhances its reactivity, making it a potential candidate for further biochemical applications.
  • Phosphate Group: The dihydrogen phosphate moiety plays a critical role in intercellular signaling and energy storage, essential for cellular function.
  • Pharmaceutical Potential: Researchers are investigating compounds with similar structures for therapeutic applications, especially in oncology and virology.

In the words of biochemist Linus Pauling, "The most powerful force in the universe is not the atomic bomb; it's the everyday chemical compounds we have yet to discover." This compound exemplifies the potential within complex molecules that could revolutionize our understanding of biochemistry.

Moreover, the interactivity between the amino and hydroxyl groups presents opportunities for synthetic modifications, leading to diverse derivatives with varied biological activities. The compound exemplifies the intricate dance of chemistry and biology, reflecting the layered complexity of life at the molecular level.