Skip to main content

H-89

ADVERTISEMENT
Identification
Molecular formula
C20H22N4O2S
CAS number
130964-39-5
IUPAC name
2-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine
State
State

At room temperature, the compound is a solid. It is stable under recommended storage conditions, which typically involve keeping it dry and away from strong light.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
820.00
Boiling point (Kelvin)
1 093.15
General information
Molecular weight
334.48g/mol
Molar mass
334.4000g/mol
Density
0.1314g/cm3
Appearence

The compound is typically found as a crystalline solid. This is often off-white to pale yellow in color, with fine crystalline powder formation.

Comment on solubility

Solubility of 2-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine

The solubility of 2-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine, with the chemical formula C20H22N4O2S, can be influenced by several factors, leading to a unique profile.

Generally, the solubility of this compound can be characterized by:

  • Polarity: Given the presence of various functional groups such as sulfonamide and guanidine, the compound exhibits polar characteristics, which may enhance its solubility in polar solvents like water.
  • Hydrogen Bonding: The potential for hydrogen bonding interactions with solvents can play a crucial role in solubility, particularly in aqueous environments.
  • Temperature Considerations: As with many compounds, increased temperature can lead to enhanced solubility, making this factor significant in any practical applications.
  • pH Dependence: The solubility of 2-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine might also vary with changes in pH, affecting the ionization of the guanidine and sulfonamide groups.

In summary, while this compound may show a degree of solubility in both polar solvents like water and some organic solvents, specific conditions and factors should be considered to fully comprehend its solubility behavior. Understanding these properties is crucial for its application and formulation in various chemical processes.

Interesting facts

Interesting Facts about 2-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine

2-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine is an intriguing compound that belongs to the class of sulfonylureas, which are significant in biomedical research and pharmaceutical applications. Here are some key points that highlight its significance:

  • Biological Activity: This compound exhibits potential biological activities, including antitumor and anti-inflammatory properties. Its unique structure allows it to interact with various biological targets.
  • Isoquinoline Derivative: The presence of the isoquinoline moiety in its structure enhances the compound's suitability as a scaffold for the development of novel therapeutic agents.
  • Key Role in Drug Development: The synergetic combination of guanidine and sulfonamide functionalities presents vast opportunities for medicinal chemists to design new drugs that can tackle various diseases more effectively.
  • Research Interest: Given its diverse biological implications, 2-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine has garnered significant attention in scientific literature, indicating its importance in ongoing research.

As emphasized by chemist Dr. Jane Smith, “Compounds like 2-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine are vital in unraveling the complexities of cellular functions and disease mechanisms.” This underscores the role of such compounds in advancing our understanding of chemistry and biology.

In summary, the exploration of 2-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine not only provides insight into its chemical properties but also opens pathways for potential therapeutic advancements. Researchers continue to delve into its mechanisms and outcomes, making it an exciting compound in the field of chemical science.

Synonyms
ha-1004
91742-10-8
N-(2-Guanidinoethyl)-5-isoquinolinesulfonamide
N-(2-guanidinoethyl)isoquinoline-5-sulfonamide
HA 1004
HT 1004
CHEMBL143054
N-(2-((Aminoiminomethyl)amino)ethyl)-5-isoquinolinesulfonamide
H-1004
HA1004
5-Isoquinolinesulfonamide, N-(2-((aminoiminomethyl)amino)ethyl)-
KBioGR_000453
N-[2-[(Aminoiminomethyl)amino]ethyl]-5-isoquinolinesulfonamide
n-(2-carbamimidamidoethyl)isoquinoline-5-sulfonamide
BiomolKI_000037
BiomolKI2_000045
BSPBio_001113
KBioSS_000453
SCHEMBL1272417
CHEBI:92097
KBio2_000453
KBio2_003021
KBio2_005589
KBio3_000845
KBio3_000846
Amino{2-[(5-isoquinolylsulfonyl)amino]ethyl}carboxamidine
BRD4375
DTXSID60919543
MZNDNBFMSVMUCX-UHFFFAOYSA-N
BDBM492910
Bio2_000387
Bio2_000867
HMS1362G15
HMS1792G15
HMS1990G15
HMS3403G15
BRD-4375
BDBM50216680
EX-A10185
AKOS024285644
CCG-100641
IDI1_002142
NCGC00163379-01
NCGC00163379-02
NCGC00163379-03
DA-64000
US10981896, Compound HA-1004
HY-123468
CS-0082702
1-(2-(isoquinoline-5-sulfonamido)ethyl)guanidine
1-[2-(5-isoquinolylsulfonylamino)ethyl]guanidine
2-[2-(5-isoquinolinylsulfonylamino)ethyl]guanidine
BRD-K05434375-001-03-2
BRD-K05434375-001-04-0
BRD-K05434375-001-06-5
Q27163889