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Triethylene glycol monomethyl ether

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Identification
Molecular formula
C8H18O4
CAS number
112-35-6
IUPAC name
2-[2-(2-hydroxyethoxy)ethoxy]ethanol
State
State

At room temperature, triethylene glycol monomethyl ether is a liquid. It is known for being a stable compound under recommended storage conditions.

Melting point (Celsius)
-7.00
Melting point (Kelvin)
266.15
Boiling point (Celsius)
285.90
Boiling point (Kelvin)
559.05
General information
Molecular weight
194.23g/mol
Molar mass
194.2320g/mol
Density
1.1210g/cm3
Appearence

Triethylene glycol monomethyl ether is a clear, colorless, and odorless liquid. It is commonly used as a solvent and has hygroscopic properties, which means it can absorb moisture from the environment.

Comment on solubility

Solubility of 2-[2-(2-hydroxyethoxy)ethoxy]ethanol

The compound 2-[2-(2-hydroxyethoxy)ethoxy]ethanol, also known as triglycol alcohol, exhibits interesting solubility characteristics that are worth discussing. Its extensive ethylene glycol units contribute to the following solubility traits:

  • Highly Soluble in Water: Due to the presence of multiple hydroxyl (-OH) groups, this compound is readily soluble in water. The ability of these groups to form hydrogen bonds with water molecules enhances solubility.
  • Soluble in Organic Solvents: In addition to its aqueous solubility, 2-[2-(2-hydroxyethoxy)ethoxy]ethanol is also soluble in many organic solvents, such as ethanol and propylene glycol, making it versatile for various applications.
  • Temperature Dependence: As is common with many alcohols and glycols, solubility can vary with temperature. Increased temperatures generally enhance solubility, allowing for better mixing in formulations.

This compound's solubility in both polar and non-polar environments makes it particularly valuable in formulations where a balance between hydrophilic and lipophilic properties is essential. Thus, it finds applications in fields ranging from cosmetics to pharmaceuticals. In conclusion, the solubility of 2-[2-(2-hydroxyethoxy)ethoxy]ethanol highlights its potential versatility and effectiveness.

Interesting facts

Interesting Facts about 2-[2-(2-hydroxyethoxy)ethoxy]ethanol

2-[2-(2-hydroxyethoxy)ethoxy]ethanol is an intriguing compound that exemplifies the fascinating world of polyalcohols, which are known for their versatility in various applications. Here are some key facts about this compound:

  • Structure: This compound features a branched chain of ethylene glycol units, characteristic of its repetitive ether and alcohol functional groups, making it water-soluble and creating strong hydrogen bonding capabilities.
  • Applications: It is commonly used in:
    • Cosmetic formulations, as a humectant that helps maintain moisture.
    • Pharmaceutical applications, due to its ability to enhance the solubility of drugs.
    • Industrial products, such as surfactants and emulsifiers in detergents and cleaning agents.
  • Biocompatibility: The presence of hydroxyl groups in its structure often lends the compound enhanced biocompatibility, making it suitable for applications in the medical field.
  • Surfactant Properties: Its molecular architecture allows it to act effectively as a surfactant, reducing surface tension and aiding in the mixing of oil and water.

Overall, the compound's unique features not only enhance its practicality across various domains but also make it a compelling subject of study for both chemists and industry professionals. As we continue to explore new methodologies and formulations, 2-[2-(2-hydroxyethoxy)ethoxy]ethanol remains at the forefront of innovative chemical solutions.

Synonyms
TRIETHYLENE GLYCOL
112-27-6
Triglycol
2,2'-(Ethane-1,2-diylbis(oxy))diethanol
2,2'-Ethylenedioxydiethanol
2-[2-(2-Hydroxyethoxy)ethoxy]ethanol
Trigen
Triethylenglykol
Triethyleneglycol
1,2-Bis(2-hydroxyethoxy)ethane
2,2'-Ethylenedioxybis(ethanol)
3,6-Dioxaoctane-1,8-diol
2,2'-(Ethylenedioxy)diethanol
2,2'-Ethylenedioxyethanol
Di-beta-hydroxyethoxyethane
Triethylene glcol
Glycol bis(hydroxyethyl) ether
Trigol
2,2'-[ethane-1,2-diylbis(oxy)]diethanol
Caswell No. 888
Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-
Ethylene glycol dihydroxydiethyl ether
TEG
Bis(2-hydroxyethoxyethane)
Ethanol, 2,2'-(ethylenedioxy)di-
2,2'-(1,2-Ethanediylbis(oxy))bisethanol
NSC 60758
HSDB 898
Ethylene glycol-bis-(2-hydroxyethyl ether)
119438-10-7
EINECS 203-953-2
EPA Pesticide Chemical Code 083501
BRN 0969357
CCRIS 8926
2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHANOL
DTXSID4021393
UNII-3P5SU53360
CHEBI:44926
AI3-01453
NSC-60758
MACROGOL 150
3P5SU53360
PEG-3
3,6-Dioxa-1,8-octanediol
Di-.beta.-hydroxyethoxyethane
DTXCID601393
Ethanol, 2,2'-(1,2-ethanediylbis(oxy))bis-
EC 203-953-2
4-01-00-02400 (Beilstein Handbook Reference)
2,2'-(ethane-1,2-diylbis(oxy))bis(ethan-1-ol)
NCGC00163798-03
2-[2-(2-hydroxyethoxy)ethoxy]ethan-1-ol
103734-98-1
122784-99-0
137800-98-7
145112-98-7
TRIETHYLENE GLYCOL (USP-RS)
TRIETHYLENE GLYCOL [USP-RS]
Triethylenglykol [Czech]
MFCD00081839
2-(2-(2-hydroxyethoxy)ethoxy)ethanol
203-953-2
CAS-112-27-6
2-(2-(2-HYDROXY-ETHOXY)-ETHOXY)-ETHANOL
OH-PEG3-OH
Trigenos
triethylenglycol
triethylene-glycol
Triethyleneglycol,
Tri-ethylene glycol
MFCD00002880
3,8-diol
TEG (GLYCOL)
Triethylene glycol, puriss.
SCHEMBL14929
WLN: Q2O2O2Q
Triethylene glycol (Standard)
Ethanol,2'-(ethylenedioxy)di-
TRIETHYLENE GLYCOL [MI]
CHEMBL1235259
1,8-dihydroxy-3,6-dioxaoctane
TRIETHYLENE GLYCOL [HSDB]
TRIETHYLENE GLYCOL DIMALEATE
HY-W017440R
NSC60758
STR02345
TRIETHYLENE GLYCOL [WHO-DD]
Tox21_112073
Tox21_202440
Tox21_300306
MFCD01779596
MFCD01779599
MFCD01779601
MFCD01779603
MFCD01779605
MFCD01779609
MFCD01779611
MFCD01779612
MFCD01779614
MFCD01779615
MFCD01779616
STL282716
AKOS000120013
CS-W018156
DB02327
FT15207
HY-W017440
USEPA/OPP Pesticide Code: 083501
NCGC00163798-01
NCGC00163798-02
NCGC00163798-04
NCGC00163798-05
NCGC00163798-06
NCGC00254097-01
NCGC00259989-01
1,2-DI(BETA-HYDROXYETHOXY)ETHANE
2-[2-(2-Hydroxyethoxy)ethoxy]ethanol #
BP-21036
DA-78612
Triethylene glycol, ReagentPlus(R), 99%
Ethanol,2'-[1,2-ethanediylbis(oxy)]bis-
NS00002182
T0428
EN300-19916
2,2'-(1,2-Ethanediyl bis (oxy))-bisethanol
F71165
SBI-0653903.0001
ETHYLENE GLYCOL-BIS(2-HYDROXYETHYL)ETHER
Triethylene glycol, SAJ first grade, >=96.0%
ETHYLENE GLYCOL-BIS-(2-HYDROXYETHYL)ETHER
Q420630
SR-01000944720
Triethylene glycol, Vetec(TM) reagent grade, 98%
SR-01000944720-1
ETHANOL, 2,2'-(1,2-ETHANEDIYLBIS (OXY))BIS-
F0001-0256
Triethylene glycol, BioUltra, anhydrous, >=99.0% (GC)
Z104476078
InChI=1/C6H14O4/c7-1-3-9-5-6-10-4-2-8/h7-8H,1-6H
Triethylene glycol, United States Pharmacopeia (USP) Reference Standard