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Thiamphenicol

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Identification
Molecular formula
C12H15Cl2NO5S
CAS number
138-59-0
IUPAC name
2-[[2-[(2-formamido-4-methylsulfanyl-butanoyl)amino]-4-methyl-pentanoyl]amino]-3-phenyl-propanoic acid
State
State

At room temperature, thiamphenicol is generally in a solid crystalline state. While it typically doesn't change its state unless subjected to specific conditions such as extreme heat or solvents, it is a dry, stable compound under standard conditions.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
326.40
Boiling point (Kelvin)
599.55
General information
Molecular weight
354.30g/mol
Molar mass
354.3030g/mol
Density
1.2900g/cm3
Appearence

Thiamphenicol appears as white or greyish-white crystals. It is practically insoluble in water but soluble in acetone and methanol. The compound's crystalline structure can appear slightly translucent under adequate lighting conditions, and it generally forms as a powder or fine crystals.

Comment on solubility

Solubility of 2-[[2-[(2-formamido-4-methylsulfanyl-butanoyl)amino]-4-methyl-pentanoyl]amino]-3-phenyl-propanoic acid (C12H15Cl2NO5S)

The solubility characteristics of the compound 2-[[2-[(2-formamido-4-methylsulfanyl-butanoyl)amino]-4-methyl-pentanoyl]amino]-3-phenyl-propanoic acid are influenced by its complex molecular structure. This particular compound is expected to exhibit a range of solubility possibilities based on various factors:

  • Polarity: The presence of polar functional groups, such as the amido and carboxylic acid groups, suggests that the compound may be soluble in polar solvents like water.
  • Hydrophobic regions: The aromatic phenyl group and the aliphatic chains introduce hydrophobic characteristics that could lead to reduced solubility in non-polar solvents.
  • Salts and pH: The solubility may significantly increase in basic or acidic solutions, where ionic forms of the compound are created, enhancing solubility through ionization.
  • Temperature: Increasing temperature may also improve the solubility of this compound in a given solvent, a common trait among many organic compounds.

Overall, one could conclude that understanding the solubility of this compound requires careful consideration of its molecular interactions. As noted, "Solubility is not just a property but a trait that varies under conditions." Ultimately, specific experimental data would provide the most accurate depiction of solubility behavior for this compound.

Interesting facts

Interesting Facts About 2-[[2-[(2-formamido-4-methylsulfanyl-butanoyl)amino]-4-methyl-pentanoyl]amino]-3-phenyl-propanoic acid

This compound, with its intricate structure, provides a fascinating glimpse into the realm of biochemistry and medicinal chemistry. Here are some noteworthy aspects:

  • Complex Structure: The compound's multi-functional nature highlights the complexity often found in biologically active molecules. Its numerous functional groups suggest potential interactions with various biological targets.
  • Biological Relevance: The presence of the amino acid components points to potential roles in biological systems, possibly acting as intermediates in biochemical pathways or as precursors to important biomolecules.
  • Pharmacological Potential: The structure suggests that it may possess properties that could be explored for drug development, particularly in targeting specific receptors or pathways in the human body.
  • Synthetic Interest: The synthesis of such a complex compound captures the interest of chemists and researchers. It presents challenges that can lead to the development of novel synthetic methodologies.

As a vibrant example of the intersection between chemistry and biology, this compound exemplifies the potential for novel medicinal applications. The complexity and unique functional groups offer exciting opportunities for research and development in pharmaceutical sciences.

In the words of scientific exploration, "The greater the obstacle, the more glory in overcoming it." The synthesis and study of compounds like this challenge chemists to push the boundaries of knowledge and innovation.

Synonyms
N-FORMYLMETHIONYL-LEUCYLPHENYLALANINE
2-[[2-[(2-formamido-4-methylsulfanylbutanoyl)amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid
fMLP;N-Formyl-MLF
LO6AVJ8RCE
Formyl-Met-Leu-Phe-OH
N-formylmethionylleucylphenylalanine
NSC-350593
For-Met-Leu-Phe-OH
UNII-LO6AVJ8RCE
Spectrum2_000008
Spectrum3_001520
Spectrum4_001047
Spectrum5_000682
For-Met-Leu-Phe; FMLP
SCHEMBL39528
BSPBio_003199
KBioGR_001314
DivK1c_000587
SPECTRUM1502173
SPBio_000015
HMS501N09
KBio1_000587
KBio3_002699
CHEBI:111167
NINDS_000587
HMS3373L20
HMS3746O15
PCT-4066-V
PCT-4066
CCG-40032
NSC350593
AKOS024287990
NSC 350593
IDI1_000587
NCGC00096001-01
NCGC00096001-02
DB-053486
BRD-A27693633-001-02-9
Q27190628
L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)-
2-[[2-[[2-formamido-4-(methylthio)-1-oxobutyl]amino]-4-methyl-1-oxopentyl]amino]-3-phenylpropanoic acid