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Atracurium besylate

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Identification
Molecular formula
C65H82Cl2N2O14
CAS number
64228-81-5
IUPAC name
2-[[2-[2-[diethyl-[(2-methoxyphenyl)methyl]ammonio]ethylamino]-2-oxo-acetyl]amino]ethyl-diethyl-[(2-methoxyphenyl)methyl]ammonium;dichloride
State
State

Atracurium besylate is typically found as a solid at room temperature, specifically as a crystalline powder that is used to prepare aqueous solutions for injection purposes.

Melting point (Celsius)
115.50
Melting point (Kelvin)
388.65
Boiling point (Celsius)
519.15
Boiling point (Kelvin)
792.30
General information
Molecular weight
768.18g/mol
Molar mass
768.1800g/mol
Density
1.2000g/cm3
Appearence

Atracurium besylate appears as a white to yellowish powder or crystalline solid. It is typically odorless and is soluble in water, which facilitates its use in solution form for medical applications.

Comment on solubility

Solubility of 2-[[2-[2-[diethyl-[(2-methoxyphenyl)methyl]ammonio]ethylamino]-2-oxo-acetyl]amino]ethyl-diethyl-[(2-methoxyphenyl)methyl]ammonium;dichloride

The solubility characteristics of this complex compound are quite intriguing, primarily due to its structural composition and the presence of ionic constituents. In general, the solubility of a compound, especially in polar solvents like water, can often be predicted by the following factors:

  • Ionic Nature: The presence of the dichloride moiety suggests that the compound may be highly soluble in polar solvents.
  • Ammonium Groups: The multiple ammonium groups typically increase solubility as they can form hydrogen bonds with water molecules.
  • Hydrophobic Interaction: However, the inclusion of organic groups such as (2-methoxyphenyl)methyl may hinder solubility somewhat in highly polar environments.
  • Temperature Dependence: Solubility may also vary significantly with temperature, where increased temperatures generally enhance solubility for many compounds.

Moreover, it is essential to note that the maximum solubility can be influenced by factors such as:

  1. pH Levels: The solubility might increase in acidic or basic mediums where the functional groups can be protonated or deprotonated.
  2. Presence of Other Ions: Other ions in solution can affect the solubility through common ion effects or by altering the ionic environment.
  3. Concentration: Higher concentrations might lead to saturation, decreasing solubility for that specific environment.

In summary, while this compound is likely to be soluble in polar solvents due to its ionic characteristics, its actual solubility can greatly vary based on environmental conditions and the interactions of various moieties within its structure. Thus, an experimental approach may be necessary to determine the precise solubility under different conditions.

Interesting facts

Interesting Facts about 2-[[2-[2-[diethyl-[(2-methoxyphenyl)methyl]ammonio]ethylamino]-2-oxo-acetyl]amino]ethyl-diethyl-[(2-methoxyphenyl)methyl]ammonium; dichloride

This compound is a fascinating example of a quaternary ammonium salt, showcasing the intricate nature of organic chemistry. Its structure features multiple functional groups that contribute to its unique properties and potential applications in various fields. Here are some interesting aspects worth noting:

  • Pharmaceutical Potential: Compounds like this one often serve as pharmaceutical agents, particularly due to their ability to interact with biological membranes.
  • Customization: The inclusion of a methoxyphenyl group allows for significant customization in biological interaction, making it easier to optimize for specific medicinal purposes.
  • Ammonium Salts: As a quaternary ammonium compound, it may exhibit antimicrobial properties, which has caught the attention of researchers in the field of antimicrobial agents.
  • Education in Organic Chemistry: This compound is a perfect example of the concepts of functionalization and structure-activity relationship (SAR) in organic chemistry, illustrating how small changes in structure can have significant impacts on activity.

Quaternary ammonium compounds have paved the way for innovations in drug design due to their high solubility and bioavailability. Their role in the pharmaceutical industry cannot be understated, providing valuable insights into drug delivery mechanisms. The study of such complex molecules is essential for any aspiring chemist or biochemical researcher seeking to deepen their understanding of chemical properties and interactions.

Engaging with compounds like this one opens avenues for future research, as scientists continue to explore their capabilities and applications in medicine and beyond. As they say in the field of chemistry, "Every compound tells a story," and the narratives surrounding compounds such as this one are nothing short of captivating.

Synonyms
Win 8078
Methoxyambenonium chloride
AMMONIUM, (OXALYLBIS(IMINOETHYLENE))BIS(DIETHYL(o-METHOXYBENZYL)-, DICHLORIDE
(Oxalybis(iminoethylene))bis(diethyl(o-methoxybenzyl)ammonium chloride)
152-23-8
Benzenemethanaminium, N,N'-((1,2-dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl))bis(N,N-diethyl-2-methoxy-, dichloride