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Tetraethylene glycol monooctyl ether

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Identification
Molecular formula
C16H34O5
CAS number
52625-13-5
IUPAC name
2-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]ethanol
State
State

At room temperature, Tetraethylene glycol monooctyl ether is a liquid. It is typically not very viscous and has the fluidity characteristic of similar ether compounds.

Melting point (Celsius)
-10.00
Melting point (Kelvin)
263.15
Boiling point (Celsius)
268.00
Boiling point (Kelvin)
541.15
General information
Molecular weight
306.46g/mol
Molar mass
306.4590g/mol
Density
0.9815g/cm3
Appearence

Tetraethylene glycol monooctyl ether is a clear, colorless liquid. It is characterized by its lack of color and a transparent, watery appearance.

Comment on solubility

Solubility of 2-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]ethanol (C16H34O5)

The compound 2-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]ethanol exhibits intriguing solubility characteristics, largely influenced by its structural features. The presence of a long hydrophobic octoxy tail suggests a strong affinity for organic solvents, whereas the multiple ethoxy groups provide potential for hydrogen bonding. This dual nature results in a unique solubility profile:

  • Good Solubility in Organic Solvents: The octoxy chain facilitates solvation in organic matrices, making it soluble in ethyl acetate, hexane, or other non-polar solvents.
  • Moderate Solubility in Water: While its hydrophobic characteristics limit complete solubility in water, the presence of multiple ethoxy groups allows for partial solubility, particularly at higher temperatures.
  • Temperature Dependency: Solubility can increase with rising temperatures, which aids in overcoming the hydrophobic interactions of the long carbon chain.

In summary, understanding the solubility of this compound is essential for applications in formulations, where both hydrophilic and lipophilic properties are exploited. As such, this compound illustrates the delicate balance between hydrophobicity and hydrophilicity in determining solubility parameters.

Interesting facts

Interesting Facts about 2-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]ethanol

2-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]ethanol, often referred to in the context of its structurally complex nature, holds a significant place in the world of chemical compounds due to its multifunctional applications.

Structure and Functionality

  • Multifunctional Ether: This compound contains multiple ether linkages, which contribute to its solubility properties and molecular interactions.
  • Hydrophilic and Hydrophobic Regions: The presence of an octoxy chain provides hydrophobic characteristics, while the ethylene glycol units impart hydrophilicity, making it a versatile compound for various applications.

Applications

  • Emulsifier: It is often used in the formulation of emulsions, particularly in cosmetics and pharmaceutical products, due to its excellent surfactant properties.
  • Solubilizing Agent: The compound plays a crucial role in enhancing the solubility of hydrophobic substances in aqueous solutions, facilitating better absorption in biological applications.
  • Chemical Intermediate: It serves as an important intermediate in the synthesis of more complex compounds, demonstrating its value in organic synthesis.

Research and Development

Ongoing research continues to explore the potential applications of this compound in various fields including biotechnology and materials science. Its unique properties could lead to innovative developments, particularly in:

  • Drug Delivery Systems: The ability to modify the solubility and bioavailability of pharmaceutical compounds.
  • Nanotechnology: The role of such compounds in developing nanoscale materials with enhanced properties.

Quote from a Scientist

As one researcher noted, “The versatility of 2-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]ethanol is a testament to how complex structures can lead to simple yet profound applications.”

This compound exemplifies the beauty and intricacy of chemical structure, showcasing how tailored molecules can offer solutions across a spectrum of scientific disciplines.

Synonyms
19327-39-0
3,6,9,12-tetraoxaicosan-1-ol
TETRAETHYLENE GLYCOL MONOOCTYL ETHER
(Hydroxyethyloxy)tri(Ethyloxy)octane
3,6,9,12-Tetraoxaeicosan-1-ol
2-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]ethanol
Tetraethylene glycol monoctyl ether
C8E4
tetraethyleneglycol monooctyl ether
Octyl tetraethylene glycol ether
DTXSID3066479
MFCD00043033
Octyltetraglycol
KE5RN26WTE
SCHEMBL185557
DTXCID0036057
CHEBI:41323
etraethyleneglycol monooctyl ether
Tetraethylene glycol, octyl ether
AKOS027320403
DB04233
DT15552
HY-W049715
AS-59421
CS-0103110
NS00071126
F14816
Q27095056
Tetraethylene glycol monooctyl ether, liquid, >=98% (GC)
627-661-3