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Paroxetine

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Identification
Molecular formula
C19H20ClNO
CAS number
61869-08-7
IUPAC name
2-[2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine
State
State

At room temperature, paroxetine exists as a solid. Its stable solid form is beneficial for its storage and handling in pharmaceutical applications.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
316.40
Boiling point (Kelvin)
589.60
General information
Molecular weight
329.82g/mol
Molar mass
329.8230g/mol
Density
1.3000g/cm3
Appearence

Paroxetine is typically encountered as a white to off-white powder. It is crystalline in nature and has no significant odor.

Comment on solubility

Solubility of 2-[2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine

The solubility of the compound 2-[2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine (C19H20ClNO) is significantly influenced by its molecular structure. Several factors can affect its solubility in various solvents:

  • Polarity: The presence of the electron-withdrawing chlorophenyl group contributes to the overall polarity of the molecule, which is crucial in determining solubility in polar solvents.
  • Hydrogen Bonding: The amine group (-N-) in its structure can participate in hydrogen bonding, enhancing solubility in protic solvents like water.
  • Alkyl Chains: The ethoxy group adds a hydrophobic character, which may limit the solubility in highly polar solvents, favoring organic solvents instead.

In general:

  • It is likely to exhibit moderate solubility in organic solvents such as ethanol or chloroform.
  • However, in water, its solubility may be considerably lower due to the competing hydrophobic interactions of the chlorophenyl and ethoxy groups.

Overall, this compound's solubility can be understood as a balance between its hydrophilic and hydrophobic characteristics, making it essential to consider the solvent characteristics when predicting its solubility behavior.

Interesting facts

Interesting Facts about 2-[2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine

This fascinating compound, known scientifically as 2-[2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine, is more than just a complex name; it holds significant importance in various fields of chemistry and pharmacology. Here are some engaging aspects about this compound:

  • Pharmacological Potential: The structure of this compound suggests potential activity as a drug, offering insights into how various substitutions on the benzene ring can influence biological activity. Compounds containing pyrrolidine rings often show promise in medicinal chemistry.
  • Synthetic Relevance: The synthesis of such compounds can lead to a deeper understanding of reaction mechanisms and the chemistry of pyrrolidine derivatives. It serves as a prime example of how modifications can yield compounds with unique properties.
  • Structure-Activity Relationship: Studying the interactions of the different aromatic and aliphatic groups within the compound provides a rich area for research. This methodology allows chemists to optimize efficacy while minimizing side effects, a crucial goal in drug development.
  • Biological Systems: Compounds like this one often serve as the basis for understanding complex biological systems and can potentially lead to the development of treatments for various diseases, depending on their pharmacodynamics.

In conclusion, the diverse applications and intricacies of 2-[2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine make it a compound worthy of thorough exploration within the realms of chemistry and its practical applications. As researchers delve deeper, this compound could very well contribute to advancements in pharmaceutical sciences and beyond.

Synonyms
Clemastinum
Meclastine
7723-51-5
2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine
2-[2-[1-(4-chlorophenyl)-1-phenyl-ethoxy] ethyl]-1-methylpyrrolidine
2-{2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine
Fuyosyosin
SR-01000075789
2-(2-(1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine
Alphamin free base
N-methyl-2-[2-(
Lopac0_000260
Oprea1_666556
SCHEMBL727373
CHEMBL315157
DTXSID80860149
YNNUSGIPVFPVBX-UHFFFAOYSA-N
NSC293370
AKOS015960880
CCG-204355
NSC-293370
SDCCGSBI-0050248.P002
MRF-0000766
NCGC00015281-02
NCGC00015281-03
NCGC00015281-04
NCGC00015281-06
NCGC00162107-01
AC-12474
DB-355402
NS00008833
EN300-18625383
SR-01000075789-6
2-(2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl)-1-methylpyrrolidine #
(+)-(2R)-2-[2-[[(R)-p-Chloro-.alpha.-methyl-.alpha.-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine