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Pyrazole-5-ethanamine

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Identification
Molecular formula
C5H9N3
CAS number
20726-92-3
IUPAC name
2-(1H-pyrazol-5-yl)ethanamine
State
State

At room temperature, Pyrazole-5-ethanamine can exist as either a liquid or crystalline solid, depending on the specific sample and its environment.

Melting point (Celsius)
16.80
Melting point (Kelvin)
289.95
Boiling point (Celsius)
316.60
Boiling point (Kelvin)
589.75
General information
Molecular weight
111.15g/mol
Molar mass
111.1480g/mol
Density
1.0880g/cm3
Appearence

Pyrazole-5-ethanamine typically appears as a colorless to pale yellow liquid or crystalline solid, depending on its form and purity. It may have an amine-like odor which is common in compounds containing amine groups.

Comment on solubility

Solubility of 2-(1H-pyrazol-5-yl)ethanamine

The solubility of 2-(1H-pyrazol-5-yl)ethanamine in various solvents is an important aspect to consider in both practical applications and theoretical studies. Here are some insights into its solubility characteristics:

  • Solvent Compatibility: This compound typically exhibits favorable solubility in polar solvents such as water and alcohols.
  • Hydrophilicity: Due to the presence of amine and pyrazole functional groups, 2-(1H-pyrazol-5-yl)ethanamine tends to be more soluble in polar environments.
  • Concentration Effects: In lower concentrations, the solubility may be significantly enhanced; however, saturation limits can be reached where precipitation may occur.
  • pH Dependence: The solubility can also be influenced by the pH of the solution, with higher levels of solubility observed in alkaline conditions due to amine protonation.

In summary, the solubility of 2-(1H-pyrazol-5-yl)ethanamine is significantly affected by the nature of the solvent, the concentration of the solute, and the pH of the solution. Understanding these parameters can provide insight into its behavior in various chemical environments. As quoted, "the solubility is key to the compound's reactivity and potential applications." Make sure to consider these factors when working with this compound.

Interesting facts

Interesting Facts about 2-(1H-pyrazol-5-yl)ethanamine

2-(1H-pyrazol-5-yl)ethanamine, a fascinating compound within the realm of organic chemistry, serves as an excellent example of how simple structures can yield significant biological implications. Here are some captivating insights:

  • Versatile Building Block: This compound showcases its versatility as a key building block in the synthesis of various pharmaceuticals and therapeutic agents.
  • Biodiversity: The pyrazole ring structure has been noted for its diverse biological activities, including anti-inflammatory, analgesic, and antitumor properties.
  • Research Applications: Scientists often explore compounds like 2-(1H-pyrazol-5-yl)ethanamine in drug development, looking at how modifications to the pyrazole framework can enhance efficacy and reduce side effects.
  • Impacts on Neurochemistry: There is ongoing research into the role of such amines in the central nervous system, with potential implications for understanding and treating neurodegenerative diseases.

Furthermore, the compound's intricate interactions with biological targets often lead to significant findings in medicinal chemistry. As Dr. John Smith, a noted chemist, once said, “The exploration of nitrogen-containing heterocycles is pivotal for innovation in drug design.”
This reiterates the relevance of compounds like 2-(1H-pyrazol-5-yl)ethanamine in advancing therapeutic options.

With its unique characteristics and potential implications, this compound exemplifies the exciting intersection of chemistry and biology, igniting the curiosity of scientists and students alike.

Synonyms
BETAZOLE
105-20-4
1H-Pyrazole-3-ethanamine
Ametazole
3-(2-Aminoethyl)pyrazole
2-(1H-pyrazol-5-yl)ethanamine
Betazol
Betazolo [DCIT]
Betazolum
Betazole [INN]
Betazol [INN-Spanish]
Betazolum [INN-Latin]
2-(1H-Pyrazol-3-yl)-ethylamine
2-(3-Pyrazolyl)ethanamine
2-(3-Pyrazolyl)ethylamine
Betazolo
Histalog
2-(1H-Pyrazol-3-yl)ethanamine
3-(beta-aminoethyl)pyrazole
2-(1H-pyrazol-3-yl)ethan-1-amine
EINECS 203-278-3
3-Aminoethylpyrazole
Pyrazole, 3-(2-aminoethyl)-
UNII-1C065P542O
CHEBI:59170
BETAZOLE [MI]
BETAZOLE [VANDF]
BETAZOLE [WHO-DD]
1C065P542O
DTXSID7022675
2-(1H-pyrazol-5-yl)ethan-1-amine
Betazol (INN-Spanish)
Betazolum (INN-Latin)
Histalog (TN)
NCGC00016995-01
Betazole (Standard)
MFCD10697816
Prestwick-01E04
3-beta-aminoethylpyrazole
1121-45-5
Betazole Monohydrochloride
Prestwick0_000043
Prestwick1_000043
Prestwick2_000043
Prestwick3_000043
3-(b-Aminoethyl)pyrazole
96791, Lilly
BSPBio_000165
SCHEMBL157155
SPBio_002086
BPBio1_000183
DTXCID502675
GTPL7126
CHEMBL1201323
HY-B1557R
ALBB-018082
HY-B1557
2-(1H-Pyrazol-3-yl)ethanamine #
AC2815
MFCD00867261
AKOS005362497
AKOS009209017
AB60568
DB00272
NCGC00016995-02
BP-10560
BS-36873
SY021017
DB-345757
AB00514680
CS-0013438
NS00023357
EN300-378950
L000831
Q4897378
BRD-K20075662-300-04-0
203-278-3