Skip to main content

Tryptamine

ADVERTISEMENT
Identification
Molecular formula
C10H12N2
CAS number
61-54-1
IUPAC name
2-(1H-indol-3-yl)ethanamine
State
State

At room temperature, tryptamine exists as a solid. It is often handled and stored in powdered or crystalline form to preserve stability.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
378.00
Boiling point (Kelvin)
651.15
General information
Molecular weight
160.22g/mol
Molar mass
160.2190g/mol
Density
1.2300g/cm3
Appearence

Tryptamine is typically a solid with a crystalline appearance. It can appear as off-white or pale yellow crystals. The compound can sometimes exhibit a somewhat hygroscopic nature, which means it may absorb moisture from the air.

Comment on solubility

Solubility of 2-(1H-indol-3-yl)ethanamine

2-(1H-indol-3-yl)ethanamine, with the chemical formula C10H12N2, showcases intriguing solubility characteristics owing to its organic structure. Understanding its solubility behavior is essential for applications in various fields such as pharmacology and biochemistry. Here are some key points regarding its solubility:

  • Polar vs. Nonpolar: The presence of an amine group in the molecule enhances its polarity, which typically increases its solubility in polar solvents, particularly water.
  • Solvent Compatibility: 2-(1H-indol-3-yl)ethanamine is likely soluble in organic solvents like ethanol and methanol, while being less soluble in nonpolar solvents due to the hydrophilic nature of the amine group.
  • Temperature Influence: As is common with many organic compounds, solubility can improve with an increase in temperature, making higher temperatures favorable for dissolving this compound.
  • pH Sensitivity: The solubility of this amine may also be affected by pH levels, as the protonation of the amine group could enhance solubility in acidic conditions.

In summary, the solubility of 2-(1H-indol-3-yl)ethanamine can be considered moderate in water but may vary significantly depending on the solvent, temperature, and pH conditions. Understanding these parameters is crucial for optimizing its use in scientific applications.

Interesting facts

Interesting Facts about 2-(1H-indol-3-yl)ethanamine

2-(1H-indol-3-yl)ethanamine, also known as tryptamine, is a fascinating compound with significant roles in both biology and chemistry. Here are some intriguing aspects of this compound:

  • Biological Significance: Tryptamine is a naturally occurring monoamine alkaloid that serves as a precursor to several important neurotransmitters, including serotonin and melatonin. This positions it at the heart of many physiological processes, such as mood regulation and sleep cycles.
  • Structural Features: The compound exhibits an indole ring structure, which is a common motif in many pharmacologically active substances. The presence of this ring contributes to its unique chemical properties and reactivity.
  • Psychoactive Properties: Due to its role in the central nervous system, tryptamine derivatives are known for their psychoactive effects. Some of these effects have led to its exploration in the context of mental health treatments and psychoactive research.
  • Research Applications: In scientific studies, tryptamine and its derivatives are frequently used in pharmacological research to investigate their impacts on neurotransmitter systems, providing insights into neurological disorders and potential therapeutic avenues.
  • Future Potential: As interest grows in understanding the therapeutic potential of tryptamine-related compounds, researchers are increasingly considering their applications in areas such as mood disorders, anxiety, and even neurodegenerative diseases.

To quote one researcher, “The biochemical pathways influenced by tryptamine are crucial not just for understanding neurological health, but also for developing innovative treatments that may alter the course of mental health care.” This emphasizes the importance of 2-(1H-indol-3-yl)ethanamine within both scientific research and its potential future applications.

In summary, 2-(1H-indol-3-yl)ethanamine not only offers insights into fundamental biological processes but also lays the groundwork for ongoing research into new therapeutic possibilities.

Synonyms
tryptamine
61-54-1
2-(1H-Indol-3-yl)ethanamine
3-(2-aminoethyl)indole
1H-Indole-3-ethanamine
2-(3-Indolyl)ethylamine
Indol-3-ethylamine
Indole, 3-(2-aminoethyl)-
2-(1H-Indol-3-Yl)Ethan-1-Amine
Tryptamin
2-(Indol-3-yl)ethylamine
3-Indoleethylamine
2-(1H-indol-3-yl)ethylamine
3-Indoleethanamine
(Amino-2 ethyl)-3 indole
MFCD00005661
(Amino-2 ethyl)-3 indole [French]
3-(2-Aminoethyl)-1H-indole
2-Indol-3-ylethylamine
BRN 0125513
beta-(3-Indolyl)ethylamine
EINECS 200-510-5
.beta.-(3-Indolyl)ethylamine
422ZU9N5TV
CCRIS 8959
2-(1H-INDOL-3-YL)-ETHYLAMINE
CHEBI:16765
TRYPTAMINE [MI]
CHEMBL6640
DTXSID2075340
EC 200-510-5
5-22-10-00045 (Beilstein Handbook Reference)
NSC-165212
3-[2-Aminoethyl]indole
triptamine
UNII-422ZU9N5TV
SR-01000075589
3-indolylethylamine
TSH
Tryptamine, 98%
(3-Indolyl)ethylamine
Spectrum_000033
Spectrum2_000873
Spectrum3_001890
Spectrum4_000850
Spectrum5_001296
2-indol-3-yl-ethylamine
2-Indol-3-yl-aethylamin
3-(2-amino)ethyl indole
bmse000207
Lopac-246557
3-(beta-aminoethyl)-indole
Lopac0_000061
Oprea1_870097
SCHEMBL26725
BSPBio_003400
GTPL125
KBioGR_001459
KBioSS_000393
MLS000515794
DivK1c_000862
SPECTRUM1503922
SPBio_000945
Tryptamine, analytical standard
DTXCID3042922
SCHEMBL13006684
2-(1h-indol-3-yl) ethylamine
HMS502L04
KBio1_000862
KBio2_000393
KBio2_002961
KBio2_005529
KBio3_002903
NINDS_000862
2-(1H-indol-3-yl)-ethyl-amine
HMS1922K18
HMS2267B18
HMS3885E17
2-(1H-Indol-3-yl)ethanamine #
ALBB-017957
BCP21605
CS-D1750
HY-B2132
BBL015353
BDBM50024210
CCG-40088
s3627
STK262895
AKOS000119468
DB08653
FS-3317
SDCCGMLS-0066798.P001
SDCCGSBI-0050049.P003
IDI1_000862
NCGC00014994-01
NCGC00014994-02
NCGC00014994-03
NCGC00014994-04
NCGC00014994-05
NCGC00014994-06
NCGC00014994-07
NCGC00014994-10
NCGC00014994-11
NCGC00095081-01
NCGC00095081-02
NCGC00095081-03
NCGC00095081-04
NCGC00095081-05
BP-12561
SMR000112268
SY001383
DB-005731
Tryptamine, Vetec(TM) reagent grade, 98%
A8532
NS00006933
T0890
(Amino-2 ethyl)-3 indole;3-Indoleethylamine
EN300-20412
C00398
AE-848/30735051
L000946
Q409439
SR-01000075589-5
BRD-K44218819-001-05-1
F2169-0960
Z104478080
5E7B376B-5933-446C-9D88-661B5F480122
InChI=1/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H