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Dimethyltryptamine

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Identification
Molecular formula
C12H16N2
CAS number
61-50-7
IUPAC name
2-(1H-indol-3-yl)-N,N-dimethyl-ethanamine
State
State

At room temperature, dimethyltryptamine is typically in a solid state. It is often used or encountered in powdered form or crystalline form.

Melting point (Celsius)
49.00
Melting point (Kelvin)
322.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
188.27g/mol
Molar mass
188.2690g/mol
Density
1.0990g/cm3
Appearence

Dimethyltryptamine appears as a white, crystalline solid. Depending on the form and any existing impurities, it can have a yellowish tint. It is often encountered in powdered form.

Comment on solubility

Solubility of 2-(1H-indol-3-yl)-N,N-dimethyl-ethanamine (C12H16N2)

The solubility of 2-(1H-indol-3-yl)-N,N-dimethyl-ethanamine in various solvents is influenced by its chemical structure and interactions.

Key Solubility Characteristics

  • Polar Solvents: This compound is generally soluble in polar solvents like water and alcohols due to its amine groups that can form hydrogen bonds.
  • Non-polar Solvents: It shows limited solubility in non-polar solvents, attributable to the hydrophobic indole ring which hinders interactions with the solvent molecules.
  • pH Dependence: The solubility may vary with pH, as the protonation state of the amine groups can affect the overall solubility.

As a rule of thumb, “like dissolves like.” Thus, the compatibility of the compound with the solvent's polarity is crucial for its solubility. The estimated solubility range in different solvents is invaluable for practical applications in the field.

In summary, while 2-(1H-indol-3-yl)-N,N-dimethyl-ethanamine demonstrates solubility in polar environments, its behavior in non-polar solvents is more restrictive, making the knowledge of its solubility profile essential for various chemical processes.

Interesting facts

Interesting Facts about 2-(1H-indol-3-yl)-N,N-dimethyl-ethanamine

2-(1H-indol-3-yl)-N,N-dimethyl-ethanamine, often referred to as a derivative of indole, exhibits fascinating properties that attract attention within the realms of pharmacology and organic chemistry. Here are some engaging aspects to consider:

  • Indole Derivative: This compound is known for its indole structure, which is an important scaffold in many biological systems. Indoles play a crucial role in various natural products and pharmaceuticals, making this compound particularly noteworthy.
  • Biological Activity: Compounds similar to 2-(1H-indol-3-yl)-N,N-dimethyl-ethanamine have demonstrated potential as serotonin receptor modulators, which could lead to advancements in treating mood disorders and other neurological conditions.
  • Research Applications: The unique combination of nitrogen and aromatic rings in its structure makes this compound a key candidate for studies related to drug development, particularly in understanding receptor interactions and the mechanisms of action within the brain.
  • Electronics and Sensing: Beyond biological implications, indole derivatives are also being explored in the field of electronics, particularly in organic light-emitting diodes (OLEDs) and sensors due to their electronic properties.

As a compound that bridges both organic chemistry and pharmacology, 2-(1H-indol-3-yl)-N,N-dimethyl-ethanamine presents a rich tapestry of study avenues. For instance, its interaction with biological systems offers insights into how subtle structural changes can lead to significant functional variations. Furthermore, the exploration of its synthesis can lead to new methodologies in organic synthesis that are valuable for chemists looking to innovate.

In the words of a notable chemist, “Every compound tells a story — the key is to listen closely.” The study of such compounds inspires not only practical applications but also a deeper appreciation for the intricate dance of molecules that shape our world.

Synonyms
N,N-DIMETHYLTRYPTAMINE
DIMETHYLTRYPTAMINE
61-50-7
2-(3-Indolyl)ethyldimethylamine
3-(2-Dimethylaminoethyl)indole
1H-Indole-3-ethanamine, N,N-dimethyl-
2-(1H-Indol-3-yl)-N,N-dimethylethanamine
N,N-Dimethyl-1H-indole-3-ethylamine
DMT (psychogenic)
N,N-dimethyl-1H-Indole-3-ethanamine
DEA No. 7435
UNII-WUB601BHAA
3-[2-(dimethylamino)ethyl]indole
WUB601BHAA
EINECS 200-508-4
NSC 63795
BRN 0138259
CHEBI:28969
HSDB 8017
NSC-63795
N-DIMETHYLTRYPTAMINE
Indole, 3-(2-(dimethylamino)ethyl)-
CHEMBL12420
DTXSID60110053
(2-Indol-3-ylethyl)dimethylamine
Indole, 3-[2-(dimethylamino)ethyl]-
3-(2-(DIMETHYLAMINO)ETHYL)INDOLE
DIMETHYLTRYPTAMINE (MART.)
DIMETHYLTRYPTAMINE [MART.]
(psychogenic)
N,N-Dimethyltryptamine (1mg/ml in Methanol)
N,N Dimethyltryptamine
N,N-Dimethyltryptamine (1mg/ml in Acetonitrile)
2-(1H-INDOL-3-YL)-N,N-DIMETHYL-ETHANAMINE
NN-Dimethyltryptamine
Dimethyltryptamine(DMT)
dimethyltryptamine [INN]
(N,N)-Dimethyltryptamine
GTPL141
3-(dimethylaminoethyl)-indole
SCHEMBL335710
[2-(1H-INDOL-3-YL)-ETHYL]-DIMETHYL-AMINE
DTXCID4065313
METHYL-(2-(1H-INDOL-3-YL)-ETHYL)-METHYLAMINE
N,N-Dimethyltryptamine, free base
DIMETHYLTRYPTAMINE [WHO-DD]
N,N-DIMETHYLTRYPTAMINE [MI]
NSC63795
WLN: T56 BMJ D2N1&1
3-(2-(dimethylamino)ethyl)-Indole
BDBM50026868
STK370594
3-[2- (dimethylamino)ethyl]-Indole
AKOS005446117
3-(2-Dimethylaminoethyl) indole; DMT
DB01488
MB00483
[2-(1H-indol-3-yl)ethyl]dimethylamine
3-(2-DIMETHYLAMINOETHYL) INDOLE
2-(1H-indol-3-yl)-ethyl-dimethyl-amine
AS-47089
N,N-Dimethyltryptamine, >=97% (HPLC)
2-(1H-indol-3-yl)-N,N-dimethylethylamine
DB-308391
N,N-Dimethyltryptamine, 1mg/ml in Methanol
1H-INDOLE-3-ETHANAMINE,N,N-DIMETHYL
NS00005525
N,N-dimethyl-1H-Indole-3-ethanamine (9CI)
2-(1H-Indol-3-yl)-N,N-dimethylethanamine #
C08302
D-5500
L001288
Q407217
2-(1H-indol-3-yl)-N,N-dimethylethanamine (ACD/Name 4.0)
N-(2-(1H-indol-3-yl)ethyl)-N,N-dimethylamine (ACD/Name 4.0)
200-508-4
InChI=1/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H