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Corticosteroid

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Identification
Molecular formula
C21H29O8P
CAS number
.Please consult additional resources as the CAS number for complex compounds can vary.
IUPAC name
[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] dihydrogen phosphate
State
State

At room temperature, the compound is typically found in a solid, crystalline state due to its complex molecular structure.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
920.00
Boiling point (Kelvin)
1 193.15
General information
Molecular weight
502.58g/mol
Molar mass
502.5760g/mol
Density
1.2600g/cm3
Appearence

The compound appears as a white to creamy white, odorless powder. It is generally very fine and has a crystalline structure.

Comment on solubility

Solubility of [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] dihydrogen phosphate

The compound [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] dihydrogen phosphate (C21H29O8P) exhibits interesting solubility characteristics that are influenced by its structural components.

  • Hydrophilic Groups: The presence of dihydroxy and phosphate groups in the structure may impart a certain degree of hydrophilicity to the compound. As a result, it is likely to exhibit some level of solubility in polar solvents such as water.
  • Lipophilic Regions: Alternatively, the hydrophobic cyclopenta[a]phenanthrene moiety may counterbalance this effect, leading to limited solubility in water and enhanced solubility in organic solvents like ethanol or DMSO.
  • Overall Solubility: As a complex compound, its solubility may vary significantly across different solvents. Thus, it’s crucial to consider both the solvent type and the concentration when evaluating its solubility properties.

In summary, while the compound is expected to exhibit some degree of solubility in polar environments due to its functional groups, the overall solubility will be profoundly influenced by its hydrophobic characteristics. This balance of hydrophilicity and lipophilicity makes the solubility profile of this compound particularly fascinating for further studies.

Interesting facts

Interesting Facts about 2-(11,17-Dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl Dihydrogen Phosphate

This compound, often referred to by its full name or through its functional groups, is an intriguing member of the family of phosphate esters, which are widely found in biological systems. Here are some noteworthy points:

  • Biological Relevance: Phosphorylation plays a crucial role in various biological processes, serving as a regulatory mechanism for proteins and enzymes.
  • Complex Structure: This compound features a complex steroid-like backbone, indicative of its potential biological activities, making it a subject of interest in medicinal chemistry.
  • Hydroxyl Groups: The presence of multiple hydroxyl groups contributes to its polar nature, influencing its interactions and solubility in biological environments.
  • Active Research: Compounds with similar structures are often researched for their potential therapeutic applications, such as their roles in hormone signaling and cancer treatment.
  • Natural Products: Interestingly, many compounds in this class are derived from natural products or serve as analogs to naturally occurring steroids, crucial for various physiological functions.

In conclusion, the compound 2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl dihydrogen phosphate exemplifies the intricate relationship between chemical structure and biological function, serving as a bridge between organic chemistry and life sciences.

Synonyms
[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] dihydrogen phosphate
SCHEMBL24622433
DTXSID60859233
NCGC00249889-01
NS00028881
11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate